Sharif Digital Repository

Reducing the size of transistors has dramatically increased the impacts of NBTI, HCI, and EM phenomena in comparison with decade ago. These phenomena are able to have influence on properties of different parts of a chip to make it changed gradually; including threshold voltage of a transistor and electrical conductivity of interconnections. These changes are known as the aging of a transistors that diminish the performance and reliability of a chip. A common reason that plays a significant role in all these phenomena is temperature. The temperature becomes more important when the power density increases per unit area due to decreased size of transistors, which is a trend in multi-core... 

Deposition of solid particles present in the process air on the walls of furnaces is one of the challenges in industries. This phenomenon has various causes. For example, in a furnace, the temperature of particles increases as they pass in front of the furnace burners, and due to the softening of the particles, their chances of deposition increase when they collide with the walls. Over time, with the growth of deposited particle layers on the combustion chamber walls, the performance of the combustion system gradually becomes impaired. present research aims to design air jets intersecting with the process air path, with the purpose of reducing the temperature of particles prone to deposition... 

In many papers, GDP is used as a measure of economic growth, which is shown to possess a nonlinear structure. The study focuses on the nonlinear Granger causality between liquidity, government spending, oil revenues and economic growth by markov-switching vector autoregressive and markov- switching Granger causality approach for the period of 1369-1397 for Iran. The empirical results from MSAI(2)-VAR(4) suggest that Oil revenues and government spending have a significant impact on economic growth in both regimes. Also, markov- switching Granger causality results are quite different from the traditional Granger causality results, that suggests the nonlinear Granger causality has more... 

Cardiovascular diseases are among the leading causes of death worldwide. For instance, in 2015, almost 31% of the world’s mortality rate was due to these causes. One of these diseases is cardiac coronary vessels’ occlusion which leads to the insufficient blood supply to the heart tissue and cardiomyocytes death after Myocardial Infarction (MI). After MI, a hierarchy of events in the heart tissue changes heart muscle and forms cardiac fibrosis. This fibrotic tissue does not have the native one’s properties and function, so it will cause cardiac arrest and patient death. Therefore, it is obvious that vascular network plays a crucial role in the heart function. The importance of cardiac... 

Cardiovascular disease (CVD) currently remains a considerable challenge for clinical treatments. CVDs account for N17.5 million deaths per year and will predictably increase to 23.6 million by 2030. The main purpose is to create human model systems to study the effect of disease mutations or drug treatment on the heart. In addition, engineered cardiac tissues are considered promising candidates to be transplanted to improve the function of diseased hearts. For engineered active tissues/organs, 3D bioprinting can fabricate complex tissue architecture with a spatiotemporal distribution of bioactive substances (cells, growth factors, and others) to better guide tissue regeneration. However,... 

Understanding biological systems requires extensive knowledge of individual parameters, and to study the processes of cell differentiation and cell behavior, a suitable environment must be created with the physiological conditions of the human body. For this purpose, with the knowledge of microfluidics, a microenvironment can be provided to study the behavior of cells on a small scale. The use of bone tissue model microfluidic chips is an alternative and new method in which it is possible to study the behavior of cells to differentiate into bone and to examine the toxicity of drugs, which in itself can help in the effective and successful treatment of these cases show. Therefore, in this... 

The use of microelectrode arrays in neural networks has offered a wonderful opportunity for evaluating numerous properties and interactions with excitable tissues such as the brain and spinal cord in the laboratory. In neural network applications, microelectrode arrays can be utilized to analyze nerve impulses or interact with neurons. They are either used to record neural data or to stimulate spinal cord nerves. Previous research has revealed that stimulating the spinal epidural region can help restore after spinal cord injuries (SCIs), which is the key to using them in the rehabilitation of living beings, including humans. According to the international campaign for the treatment of SCI... 

In this study, at first the V2O5 spent catalysts were characterized. The aim was to identifying whether these catalyst may be regenerated. Then, for feasibility study of them, three methods were applied: washing, diffusion and milling the spent catalysts for their subsequent reproduction. A variety of techniques such as XRD, XRF, AAS, TPR and TPO were applied in order to identify factors contributing in vanadium pentoxide catalysts deactivation. The results showed that approximately all of pollutants caused their performance deterioration, while they still have some active phases. Then, the polluted catalysts were washed (their yield increased from 43% to 72.2%). In the underside of the... 

Building complex and functional tissues and organs is very challenging. One of the challenges is building an efficient network of blood vessels that can be used to facilitate the transport of nutrients and oxygen to the host. In addition to using channels for oxygen supply, another solution is to use oxygen-carrying materials. In this study, in addition to designing and simulating scaffolds with multi-scale microchannels, calcium peroxide was used to release oxygen and eliminate hypoxia in the scaffold. Here alginate is used as the main material for scaffolding. In an attempt to build a scaffold using a bio-printer, pluronic acid was also used as a sacrificial material to create canals.... 

Chronic kidney disease is one of the silent diseases that progresses slowly, often without symptoms, and can eventually lead to kidney loss. Early detection of this disease can help diagnose it and prevent further problems. Urinary creatinine is an effective biomarker for early diagnosis of chronic kidney disease, but methods available in clinics are problematic for people living in disadvantaged areas because of the high cost and the need for 24-hour urine collection. Currently, paper-based microfluidic devices are being developed because they are easy to manufacture, inexpensive, the fluid is permeable by capillary force, and no additional equipment is needed. In this work, to fabricate a... 

According to today’s medicine progress, the need for improving the medical facilities have been increased. Within the human body, the biomolecules concentration gradient is regulating the cell functions. Biological processes such as immune response, wound healing, and cancer metastasis have been affected by the bimolecular concentration gradient. So understanding the cell behavior in the presence of a chemical gradient can improve the understanding from these biological processes, and also would help in medical researches. On the other hand, finding the appropriate dose of the drugs and in some cases finding the most effective drug is a clinical challenge that made a new field of research in... 

Data collected from street networks show that travel time in urban street networks is a stochastic variable, whose range of variation increases with the congestion level. Work and school trips comprise the major part of morning peak volumes, whose common characteristic is that they need to be made on time. For this reason, these travelers are pessimistic in their route choice, and try to choose routes which are more reliable. Travel time standard deviation is one of the common measures for estimating travel time reliability that is related to properties of day-to-day travel time distribution on a particular route. Based on the empirical data collected from Tehran street network, this paper... 

Noise or noise pollution, is defined as an unwanted sound, produced mostly by motor vehicles in urban areas. If the noise exceeds its limit, adverse effects on users and citizens are expected. Thus the assessment of the noise level and its comparison with allowable values is mandatory. Traffic induced noise depends upon different factors such as traffic, weather, and, sound barriers. Noise pollution study has a long history all over the world. Many studies, mostly representing the outdoor noise pollution models, have been done in recent years. This paper presents an assessment of traffic-induced noise in a heavily traveled tunnel, locally referred to as Resalat tunnel, which is located in... 

In this thesis, we introduce a novel Artificial Intelligence (AI) system inspired by the philosophical and psychoanalytical concept of imagination as a ``Re-construction of Experiences". Our AI system is equipped with an imagination-inspired module that bridges the gap between textual inputs and other modalities, enriching the derived information based on previously learned experiences. A unique feature of our system is its ability to formulate independent perceptions of inputs. This leads to unique interpretations of a concept that may differ from human interpretations but are equally valid, a phenomenon we term as ``Interpretable Misunderstanding". We employ large-scale models,... 

With the advancement of automotive industry, the number of electronic systems that need to communicate with each other has increased. An effective strategy to meet these growing demands is using bus-based protocols, which can establish safe communication among numerous nodes with reasonable cost, weight, and space requirements. The objective of this thesis is the design and implementation of a transceiver based on the FlexRay protocol. The significance of this protocol lies in its ability to provide higher data transmission rates compared to other protocols like CAN and LIN, and its role as the foundational communication medium among various domains in modern vehicle architectures. In this... 

Fabrication and characterization of different surface charged cellulose electrospun scaffolds including cellulose acetate, cellulose, carboxymethyl cellulose and quaternary ammonium cationic cellulose for biomedical applications have been reported in this research. We describe preparation of cellulosic nanofibers through the electrospinning following deacetylation cellulose acetate. Moreover, surface modification of electrospun cellulose nanofibers is carried out to obtain carboxymethyl cellulose and quaternized cellulose nanofibers, respectively. At last, the structural, morphological, mechanical, swelling, wettability and the cell culture properties of the scaffolds were analyzed and... 

In this research, non-isothermal annealing process at temperatures ranging between 400°C to 830 °C was investigated in warm and cold-rolled austenitic stainless steel 304L. First, the wide variety of austenitic to martensitic structure was produced by the multi-pass rolling process at room temperature -8 °C, 200 °C, and 280°C. The n exponent in Olson-Cohen equation was governed 2.83 after non-linear curve fitting to assess the fraction of deformation-induced martensite as a function of strain. Afterward, Abaqus/Explicit method was utilized to achieve the stored energy and plastic strains distribution through the thickness. Then, Cellular automata and Galerkin-finite element models were...