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Dynamics of HIV-1 Infection Models: Saturation Infection, an Eclipse Stage, CTL Immune Response
, M.Sc. Thesis Sharif University of Technology ; Hesaaraki, Mahmoud (Supervisor)
Abstract
In this thesis, three mathematical models are considered for the viral dynamics of HIV-1. The first model is an HIV infection model with saturation infection and intracellular delay, which forms a three-dimensional differential equations system, the second model includes an eclipse stage of infected cells, The viral dynamics of this model is described by four nonlinear ordinary differential equations, and finally, we study a delayed six-dimensional HIV model with CTL immune response, in fact, the main issue is the analysis of the second model (model including an eclipse stage for the infected cells).In this thesis is obtained sufficient conditions for persistence or eradication of the...
Time of concentration of surface flow in complex hillslopes
, Article Journal of Hydrology and Hydromechanics ; Volume 61, Issue 4 , 2013 , Pages 269-277 ; 0042790X (ISSN) ; Saghafian, B ; Talebi, A ; Ardakanian, R ; Sharif University of Technology
Versita
2013
Abstract
Time of concentration (TC) of surface flow in watersheds depends on the coupled response of hillslopes and stream networks. The important point in this background is to study the effects of the geometry and the shape of complex hillslopes on the time of concentration considering the degree of flow convergence (convergent, parallel or divergent) as well as the profile curvature (concave, straight or convex). In this research, the shape factor of complex hillslopes as introduced by Agnese et al. (2007) is generalized and linked to the TC. A new model for calculating TC of complex hillslopes is presented, which depends on the plan shape, the type and degree of profile curvature, the Manning...
A steady-state saturation model to determine the subsurface travel time (STT) in complex hillslopes
, Article Hydrology and Earth System Sciences ; Volume 14, Issue 6 , Jun , 2010 , Pages 891-900 ; 10275606 (ISSN) ; Talebi, A ; Ardakanian, R ; Shamsai, A ; Sharif University of Technology
2010
Abstract
The travel time of subsurface flow in complex hillslopes (hillslopes with different plan shape and profile curvature) is an important parameter in predicting the subsurface flow in catchments. This time depends on the hillslopes geometry (plan shape and profile curvature), soil properties and climate conditions. The saturation capacity of hillslopes affect the travel time of subsurface flow. The saturation capacity, and subsurface travel time of compound hillslopes depend on parameters such as soil depth, porosity, soil hydraulic conductivity, plan shape (convergent, parallel or divergent), hillslope length, profile curvature (concave, straight or convex) and recharge rate to the groundwater...
Artificial intelligence evaluation of COVID-19 restrictions and speech therapy effects on the autistic children’s behavior
, Article Scientific Reports ; Volume 13, Issue 1 , 2023 ; 20452322 (ISSN) ; Amelirad, O ; Moradi, Z ; Habibi, M ; Sharif University of Technology
Nature Research
2023
Abstract
In the present study, we aimed to quantify the effects of COVID-19 restrictions and speech treatment approaches during lockdowns on autistic children using CBCL and neuro-fuzzy artificial intelligence method. In this regard, a survey including CBCL questionnaire is prepared using online forms. In total, 87 children with diagnosed Autism spectrum disorders (ASD) participated in the survey. The influences of three treatment approaches of in-person, telehealth and public services along with no-treatment condition during lockdown were the main factors of the investigation. The main output factors were internalized and externalized problems in general and their eight subcategory syndromes. We...
Three-component coupling of boronic acids, amines, and carbon disulfide by a heterogeneous catalyst of copper (II) embedded in a highly porous and magnetic schiff base network of melamine
, Article Research on Chemical Intermediates ; Volume 49, Issue 10 , 2023 , Pages 4423-4441 ; 09226168 (ISSN) ; Kohestanian, M ; Sabzevari, A ; Pourjavadi, A ; Sharif University of Technology
Springer Science and Business Media B.V
2023
Abstract
In this work, the mesoporous magnetic heterogeneous catalyst was synthesized by anchoring copper (II) onto the nitrogen-rich poly (melamine) Schiff base networks magnetic nanocomposite. First, MNP (Fe3O4@SiO2) was functionalized with chlorosilane (CPTS). Then, the chlorine of these functionalized magnetic nanoparticles could react with the –NH2 groups of the melamine through a nucleophilic substitution reaction. Simultaneously, the condensation polymerization of melamine and benzene-1, 3, 5-tricarbaldehyde was carried out in the presence of surface-modified magnetic nanoparticles. Later, Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermogravimetric analysis...
Targeted Theranostic Delivery System Based on Liposomes Containing Graphene Quantum Dots and Drug Nanoparticles For Monitoring and Treatment of Breast Cancer
, Ph.D. Dissertation Sharif University of Technology ; Simchi, Abdolreza (Supervisor) ; Sabzevari, Omid (Supervisor)
Abstract
Theranostic liposomes have recently found a broad range of applications in nanomedicine due to stability, the high solubility of biomacromolecules, bioavailability, efficacy, and low adverse effects. However, the limitations of liposomes concerning the short systemic circulation in the body, limited controllability of the release rate, and the inability of in vivo imaging remain challenging. Herein, the development of novel hybrid ultrasound-activated piezoelectric nanoparticles based on a hybrid liposome nanocarrier composed of poly(vinylidene fluoride‐trifluoroethylene), graphene quantum dots (GQDs), and Silibinin (a hydrophobic drug) is presented. The hybrid nanoparticles are an...
Production Study of Protease Enzyme by Immobilized Cells
,
M.Sc. Thesis
Sharif University of Technology
;
Yaghmaei, Soheila
(Supervisor)
;
Kazemi, Akhtarelmolook
(Supervisor)
Abstract
Microbial proteases are among the most important hydrolytic enzymes and havebeen studied extensively since the advent of enzymology. They are essentialconstituents of all forms of life on earth, including prokaryotes, fungi, plants andanimals.In recent years there has been a phenomenal increase in the use of alkaline protease asindustrial catalysts. Alkaline proteases (EC.3.4.21–24, 99) are defined as thoseproteases which are active in a neutral to alkaline pH range. Cell immobilization is a technique that restricts the free movements of microorganisms in the process and it has a lot of advantages including this fact that biotechnologists’ dream for using continuous system in fermentation...
Alkaline protease production by immobilized cells using B. licheniformis
, Article Scientia Iranica ; Volume 20, Issue 3 , 2013 , Pages 607-610 ; 10263098 (ISSN) ; Kazemi, A ; Nahid, P ; Yaghmaei, S ; Sabzevari, M. A ; Sharif University of Technology
2013
Abstract
In recent years there has been potential increase in the use of alkaline protease as industrial catalysts. Many major industrial and commercial applications, such as food and textile industries, and medical diagnoses, are highly dependent on the protease enzyme. In the cell immobilization technique, the free movement of microorganisms is restricted in the process, and a continuous system of fermentation can be used. In the present work, this technique has been used for alkaline protease production using different carriers, such as chitosan, corn cob and corn tassel. Enzyme activity before immobilization (72 h) was 78.3 U/ml. Corn cob, with 65% immobilization capacity and the highest enzyme...
Cobalt -mediated radical polymerization of vinyl acetate in a packed column system: simultaneous effective control of molecular weight, separation, and purification
, Article Journal of Polymer Research ; Volume 29, Issue 12 , 2022 ; 10229760 (ISSN) ; Dadkhah, A. S ; Kohestanian, M ; Mahdieh, A ; Semsarzadeh, M. A ; Sharif University of Technology
Springer Science and Business Media B.V
2022
Abstract
The simultaneous control of the molecular weight, separation, and purification of polyvinyl acetate was achieved using a cobalt-mediated radical polymerization (CMRP) in a packed column with silica gel particles (PC-CMRP). The controlled radical polymerization of VAc in the packed columns was evaluated from the linear time dependence of Ln[M]0/[M], linear increase of molecular weight with the increase in conversion, and narrow molecular weight distribution. PC-CMRP method was used to produce high-purity polymers with controlled molecular weight and narrow molecular weight distribution without requiring additional purification steps. The high ability of silica gel particles to adsorb free...
Microstructural evolution and Bio-corrosion behavior of a CP-Ti processed by multi-pass of severe plastic deformation
, Article JOM ; Volume 74, Issue 12 , 2022 , Pages 4621-4631 ; 10474838 (ISSN) ; Famil Hatami, M ; Hoseini Sabzevari, S. A ; Moosavi Nezhad, S. M ; Mandanipour, V ; Szpunar, J. A ; Sharif University of Technology
Springer
2022
Abstract
The microstructure evaluation and phase transformation of multi-pass friction stir-processed (FSP) commercially pure titanium were investigated using optical microscopy, scanning electron microscopy equipped with a backscatter detector, and electron backscatter diffractometer. The microstructure characterization shows that the grain refinement mechanism changed with the increasing number of passes. The equiaxed α grains in the untreated sample changed to lath-shaped grains surrounded by serrated grain boundaries, and produced Widmanstätten morphology during the cooling cycle of FSP. The higher micro-hardness values and bio-corrosion resistances of the FSP-treated samples are due to their...
Majorana zero-energy mode and fractal structure in fibonacci-kitaev chain
, Article Journal of the Physical Society of Japan ; Volume 86, Issue 11 , 2017 ; 00319015 (ISSN) ; Sugimoto, T ; Tohyama, T ; Sharif University of Technology
2017
Abstract
We theoretically study a Kitaev chain with a quasiperiodic potential, where the quasiperiodicity is introduced by a Fibonacci sequence. Based on an analysis of the Majorana zero-energy mode, we find the critical p-wave superconducting pairing potential separating a topological phase and a non-topological phase. The topological phase diagram with respect to Fibonacci potentials follow a self-similar fractal structure characterized by the box-counting dimension, which is an example of the interplay of fractal and topology like the Hofstadter's butterfly in quantum Hall insulators. © 2017 The Physical Society of Japan
Accelerating federated edge learning
, Article IEEE Communications Letters ; Volume 25, Issue 10 , 2021 , Pages 3282-3286 ; 10897798 (ISSN) ; Balef, A. R ; Dinh, C. T ; Tran, N. H ; Ngo, D. T ; Anh Le, T ; Vo, P. L ; Sharif University of Technology
Institute of Electrical and Electronics Engineers Inc
2021
Abstract
Transferring large models in federated learning (FL) networks is often hindered by clients' limited bandwidth. We propose $ extsf {FedAA}$ , an FL algorithm which achieves fast convergence by exploiting the regularized Anderson acceleration (AA) on the global level. First, we demonstrate that FL can benefit from acceleration methods in numerical analysis. Second, $ extsf {FedAA}$ improves the convergence rate for quadratic losses and improves the empirical performance for smooth and strongly convex objectives, compared to FedAvg, an FL algorithm using gradient descent (GD) local updates. Experimental results demonstrate that employing AA can significantly improve the performance of FedAvg,...
Study of the effect of thermal dispersion on internal natural convection in porous media using fourier series
, Article Transport in Porous Media ; Volume 131, Issue 2 , 2020 , Pages 537-568 ; Graf, T ; Tran, T. V ; Ataie Ashtiani, B ; Simmons, C. T ; Younes, A ; Sharif University of Technology
Springer
2020
Abstract
Natural convection in a porous enclosure in the presence of thermal dispersion is investigated. The Fourier–Galerkin (FG) spectral element method is adapted to solve the coupled equations of Darcy’s flow and heat transfer with a full velocity-dependent dispersion tensor, employing the stream function formulation. A sound implementation of the FG method is developed to obtain accurate solutions within affordable computational costs. In the spectral space, the stream function is expressed analytically in terms of temperature, and the spectral system is solved using temperature as the primary unknown. The FG method is compared to finite element solutions obtained using an in-house code...
A probabilistic artificial neural network-based procedure for variance change point estimation
, Article Soft Computing ; Vol. 19, issue. 3 , May , 2014 , pp. 691-700 ; ISSN: 14327643 ; Niaki, S. T. A ; Moghadam, A. T ; Sharif University of Technology
2014
Abstract
Control charts are useful tools of monitoring quality characteristics. One of the problems of employing a control chart is that the time it alarms is not synchronic with the time when assignable cause manifests itself in the process. This makes difficult to search and find assignable causes. Knowing the real time of manifestation of assignable cause (change point) helps to find assignable cause(s) sooner and eases corrective actions to be taken. In this paper, a probabilistic neural network (PNN)-based procedure was developed to estimate the variance change point of a normally distributed quality characteristic. The PNN was selected based on trial and error among different types of...
Two studies of framework-usage templates extracted from dynamic traces
, Article IEEE Transactions on Software Engineering ; Volume 38, Issue 6 , 2012 , Pages 1464-1487 ; 00985589 (ISSN) ; Czarnecki, K ; Binder, W ; Bartolomei, T. T ; Sharif University of Technology
2012
Abstract
Object-oriented frameworks are widely used to develop new applications. They provide reusable concepts that are instantiated in application code through potentially complex implementation steps such as subclassing, implementing interfaces, and calling framework operations. Unfortunately, many modern frameworks are difficult to use because of their large and complex APIs and frequently incomplete user documentation. To cope with these problems, developers often use existing framework applications as a guide. However, locating concept implementations in those sample applications is typically challenging due to code tangling and scattering. To address this challenge, we introduce the notion of...
On the throughput and outage probability of multi-relay networks with imperfect power amplifiers
, Article IEEE Transactions on Wireless Communications ; Volume 14, Issue 9 , May , 2015 , Pages 4994-5008 ; 15361276 (ISSN) ; Svensson, T ; Eriksson, T ; Nasiri Kenari, M ; Sharif University of Technology
Institute of Electrical and Electronics Engineers Inc
2015
Abstract
This paper studies the energy-limited performance of multi-relay networks. Taking the properties of the power amplifiers (PAs) into account, we derive closed-form expressions for the optimal power allocation, the outage probability and the throughput in the cases with a sum consumed energy constraint. Moreover, we analyze the diversity and the multiplexing gains of the PA-aware systems. Finally, we investigate the performance of large-scale multi-relay networks and develop efficient multi-relay systems with low cooperation overhead. The numerical and the analytical results show that the inefficiency of the PAs affects the outage probability and the throughput of the multi-relay systems...
Online jointly estimation of hysteretic structures using the combination of central difference Kalman filter and Robbins–Monro technique
, Article JVC/Journal of Vibration and Control ; 2020 ; Bakhshi, A ; Yang, T. T. Y ; Sharif University of Technology
SAGE Publications Inc
2020
Abstract
Rapid assessment of structural safety and performance right after the occurrence of significant earthquake shaking is crucial for building owners and decision-makers to make informed risk management decisions. Hence, it is vital to develop online and pseudo-online health monitoring methods to quantify the health of the building right after significant earthquake shaking. Many Bayesian inference–based methods have been developed in the past which allow the users to estimate the unknown states and parameters. However, one of the most challenging part of the Bayesian inference–based methods is the determination of the parameter noise covariance matrix. It is especially difficult when the number...
Online probabilistic model class selection and joint estimation of structures for post-disaster monitoring
, Article JVC/Journal of Vibration and Control ; 2020 ; Bakhshi, A ; Yang, T. T. Y ; Sharif University of Technology
SAGE Publications Inc
2020
Abstract
Online selection of the appropriate model and identifying its parameters based on measured vibrational data are among the challenging issues in dynamic system identification. After a severe earthquake, quick monitoring and assessment of structural health status play a crucial role in effective critical risk management for the building owners and decision-makers. The Bayesian multiple modeling approach is a suitable tool for optimal model class selection, which is used in this article mainly for improving data fitting precision, decreasing dimensions of structural unknown vector through removing unnecessary parameters, detecting the occurrence and type of predominant phenomenon related to...
Online probabilistic model class selection and joint estimation of structures for post-disaster monitoring
, Article JVC/Journal of Vibration and Control ; Volume 27, Issue 15-16 , 2021 , Pages 1860-1878 ; 10775463 (ISSN) ; Bakhshi, A ; Yang, T. T .Y ; Sharif University of Technology
SAGE Publications Inc
2021
Abstract
Online selection of the appropriate model and identifying its parameters based on measured vibrational data are among the challenging issues in dynamic system identification. After a severe earthquake, quick monitoring and assessment of structural health status play a crucial role in effective critical risk management for the building owners and decision-makers. The Bayesian multiple modeling approach is a suitable tool for optimal model class selection, which is used in this article mainly for improving data fitting precision, decreasing dimensions of structural unknown vector through removing unnecessary parameters, detecting the occurrence and type of predominant phenomenon related to...
Online jointly estimation of hysteretic structures using the combination of central difference kalman filter and robbins–monro technique
, Article JVC/Journal of Vibration and Control ; Volume 27, Issue 1-2 , 2021 , Pages 234-247 ; 10775463 (ISSN) ; Bakhshi, A ; Yang, T. T. Y ; Sharif University of Technology
SAGE Publications Inc
2021
Abstract
Rapid assessment of structural safety and performance right after the occurrence of significant earthquake shaking is crucial for building owners and decision-makers to make informed risk management decisions. Hence, it is vital to develop online and pseudo-online health monitoring methods to quantify the health of the building right after significant earthquake shaking. Many Bayesian inference–based methods have been developed in the past which allow the users to estimate the unknown states and parameters. However, one of the most challenging part of the Bayesian inference–based methods is the determination of the parameter noise covariance matrix. It is especially difficult when the number...