Sharif Digital Repository

Resiliency is, now, recognized as a vital characteristics of every urban transportation network. This is so, because transportation network is considered as a life-line in disastrous events, such as major earthquakes. In this respect, design of networks may be considered (1) before the incident, (2) after the incident for 72 hours, and (3) from this 72 hours on. From the point of view of (1), design of the network may be considered as strengthening important links under budget constraints to withstand the design incident, in order to be able to function properly (to help the affected people, to evacuate the populated area, etc.).Design of network based on the point of view of (2), the one... 

Domain shift is an inevitable issue when histopathological images are analyzed in a standard laboratory. This is due to the variations in tissue handling, manual procedures for sample preparation, and differences in scanners. This can result in reduced performance of machine learning algorithms trained on images from one laboratory when applied to another. In this framework, the goal of utilizing domain generalization techniques in machine learning is to develop models that perform well in different domains. This research examines various methods of dealing with the domain shift challenges within the context of detecting mitotic cells, and proposes algorithms to improve domain generalization... 

In the present study, Friction Stir Process (FSP) was used to refine the microstructure of pure commercial copper in order to improve the mechanical properties. Since FSP can be considered as a hot deformation process, theoretical Models were utilized to simulate both thermal history and strain rate distribution. Zener-Hollomon parameter (Z) was then utilized to predict the microstructure of Stir Zone (SZ) which undergoes the Dynamic Recrystallization (DRX). Temperature distribution was formulated and solved by a commercial software COMSOL Multiphysics. Strain rate was analyzed using theoretical models and the codes were written by MATLAB. The predicted grain size was not in a good agreement... 

In this project, Dissimilar Friction Stir Welding (FSW) between aluminum alloys (1100-H12 and 5083-O) and Magnesium alloy (AZ31B-O) with 3mm thickness were butt joined. Fusion welding of aluminum/magnesium alloys has failed because of forming much more intermetallic compounds. By using friction stir welded samples, effect of welding parameters such as tool travel speed, tool rotation rate, tool position respect to weld centerline, and sheet position respect to tool direction on mechanical (tensile strength, yield strength and elongation) and microstructural properties of the welds were investigated. After several tests, range of optimum parameters were obtained. In both 1100 and 5083 alloys,... 

Capsule endoscopy is a minimally invasive diagnostic technology for gastrointestinal diseases providing images from the human’s digestion system. Developing a robust and real-time localization algorithm to determine the orientation and position of the endoscopic capsule is a crucial step toward medical diagnostics. In this thesis, we propose a novel model-aided real-time localization approach to estimate the position and orientation of a magnetic endoscopic capsule swimming inside the stomach. In the proposed method, the governing equations of the motion of an ellipsoidal capsule inside the fluid, considering different hydrodynamics interactions, are derived. Then, based on the dynamic... 

The oxidation-reduction (redox) responsive micelle system is based on a diselenide-containing triblock copolymer, poly(ε-caprolactone)-bis(diselenide-methoxy poly(ethylene glycol)/poly(ethylene glycol)-folate) [PCL-(SeSe-mPEG/PEG-FA)2]. Resulting in the development of tumor-targeted delivery for hydrophobic anticancer drugs. The diselenide bond, as redox-sensitive linkage, was designed, so it is located at the hydrophilic/hydrophobic hinge to allow complete micelles collapse and efficient drug release, in redox environments. The amphiphilic block copolymers self-assembled into micelles at concentrations above the critical micelle concentration (CMC) in an aqueous environment. Dynamic light... 

In recent years, advances have been made in the field of miniaturization of the devices (in order to increase their efficiency, lessen the materials needed for the constructions and experiments, reduce costs and energy usage) resulting in the dramatic increase of surface to volume ratio in these devices. This progress has led to the dominance of surface forces which can be used to control very important interface phenomena having a special application such as electrokinetic. Using today’s manufacturing technology; it is possible to construct micro-nanochannels made from different materials such as silicon, glass, quartz, polydimethylsiloxane (PDMS), polymethyl methacrylate (PMMA) whose...