Sharif Digital Repository

Since oil prices continue to increase, energy conservation remains the prime industrial concern. Existing processes in power plants and oil refineries are not energy efficient as they should be therefore new projects can be defined to increase the energy efficiency without incurring any cost. The most appropriate utility for the processes should be explored to reduce emissions, increase the plant capacities and improve product qualities and energy efficiencies by one coherent strategic plan for the overall site which can be achieved by a full understanding of pinch technology and awareness of the available tools for applying it in practical way. Since the distillation unit of crude oil... 

To design a drug delivery system, the drug must be encapsulated within a carrier matrix. One of the main challenges in this field is encapsulating high drug doses while achieving a linear release profile at the target site to maintain drug concentration for optimal therapeutic effects. Consequently, many research groups have focused on refining fabrication techniques to maximize loading efficiency and optimize drug release profiles from delivery systems. A potential approach to addressing this issue is the direct fabrication of a controlled-release system from the active pharmaceutical ingredient (API) itself, eliminating the need for a carrier matrix. Studies have demonstrated that such... 

Osteoarthritis is a common musculoskeletal disorder and the most prevalent form of arthritis. To date, no comprehensive cure has been reported for osteoarthritis, and its clinical management remains challenging. The primary therapeutic goals in the early stages of osteoarthritis are to increase joint mobility and control disease progression by continuously releasing drugs and molecules modulating inflammatory responses and reducing pain. Smart drug delivery platforms are one of the strategies to overcome the challenges of injectable and oral medications. Additionally, drug carrier particles can have different therapeutic targets based on their size and shape. Different therapeutic... 

A 2D simulation has been carried out to study the effect of magnetic field on heat transfer and pressure drop of nanofluid flowing through a pipe filled with porous medium. The nanofluid flow is modeled as a single-phase flow, and Darcy–Brinkman–Forchheimer equation is employed to model fluid flow in porous media. A constant uniform heat flux was imposed on the walls of the cylinder, and the values of Darcy number, Hartmann number, and volume fraction of the nanoparticles were selected as 0.1, 200, and 0.2, respectively. Effects of parameters such as Reynolds number, the material of the porous medium (conductivity and porosity), and material of nanofluids have been investigated in the... 

The effect of using backpressure of air injection in a microchannel on internal flow pressure drop were investigated in this study. Multiphase flows are commonly encountered in gas and oil industries. Flow fields in production operations are often complex and include multiphase flows of gas and liquid. Previously, because of their complex nature, these flow patterns have been mostly investigated only experimentally and empirical correlations based on the experimental data. From another point of view, it is almost impossible to experimentally realize all the flow conditions for each of the flow patterns. Nowadays computer facilities provide the tool to construct and use large-scale... 

Graphene quantum dots (GQDs) as a sort of carbon-based nanomaterials are applied in a multitude of exciting areas. They are effective fluorescent probe for many potential biological and medical applications. In comparison to conventional organic fluorescent probes (organic dyes), GQDs have substantial advantages, such as photostability, excellent solubility, low cytotoxicity and biocompatibility.
In this thesis, green fluorescent GQDs have been prepared via solvothermal method from graphite powder.Various analysis methods were utilized to characterization of the product. So, several experiments on GQDs in solution and in solid substrate at room temperature have been performed. The... 

One of the new technologies for direct energy conversion at micro scale is micro thermophotovoltaic (micro TPV). The main part of a micro TPV system is micro combustor. The ultimate goal in the design of this part is reaching to a uniform and high temperature profile along the micro combustor wall. One of the ways to reach this goal in the macro scale is the porous media combustion. In the present work, a one dimensional numerical code is developed to investigate the effect of porous media on micro combustor of a micro TPV power generator. To increase the accuracy of the results, a multi-step reaction mechanism and temperature dependent thermophysical properties will be used. The numerical... 

Nowadays, water desalination is a widely-used method for producing clean and fresh water. Recent researches in this area have mostly focused on Reverse Osmosis technology which is one of the most efficient technologies in water desalination. A new idea to increase the efficiency of a recently-designed reverse osmosis membrane called “Honeycomb Carbon Nanotube Membrane” is presented through molecular dynamics simulation. Although in this study only the inlet area of the honeycomb structure which is a Y-shaped entrance, is modeled and studied, but obviously, any improvement in the membrane inlet, equals better results at outlet which means a more efficient desalination process. Present thesis... 

The aim of this study is to develop an understanding of the role of the magnetic and electric forces on the filtration performance of wet granular beds. At first, the effect of wetting is considered by locating micro water film around the square channel for particles deposition in four different Reynolds Re=1 to Re=10 number, Typically 1000 particles in different sizes (100nm-10μm) were injected to microchannel when air and water formed completely on the surface of the block. The Drag force, Brownian force, Saffman`s lift force and the gravity force are affecting the particles. After that Dielectrophoretic and Magnetophoretic forces were included in the domain for investigating the role of... 

Today, the determination and therapy of numerous illnesses, including malignant growth, relies upon the information and assessment of platelets, so blood testing and cell examination is fundamental to survey the movement of disease. The lab on a chip innovation is utilized as an extremely productive device in cell studies. The lab on a chip is used as a foundation and a substrate for making a legitimate stream for cell processes in medication. This innovation is a gadget or framework with millimeters or centimeters aspects like a chip, and it performs research facility handling on a micron-scale. In spite of the fact that it has a few impediments, it has so many values; for example, it... 

The present work illustrates the results of an experimental study of ferrofluid flow in a tube subjected to a constant heat flux on its wall and filled with permeable material under the effect of magnetic field. The aim of this project is investigating the enhancement of heat transfer and obtaining a uniform temperature distribution inside the pipe. In order to achieve this, a porous medium with a porosity of 0.39 and ferrofluid with volume fractions of 0.6, 1.0 and 1.5 are used simultaneously, in the presence of magnetic field. The experiments are held for four different Reynolds numbers of 147.1, 167.3, 184.3 and 205.1. Also, four various modes of the oscillatory magnetic field are applied... 

The microfluidic fuel cell or laminar flow-based fuel cell is a membrane-less fuel cell which typically consists of two electrodes mounted within a T- or Y-shaped microchannel. Aqueous fuel and oxidant are introduced from the two inlets of the channel and flow together side-by-side toward the end of the channel. The Reynolds number in the microchannel is low, and hence viscous forces are dominant over the inertial forces. This causes the anolyte and catholyte form a co-laminar flow inside the microchannel which is required to maintain the separation of the fuel and oxidant and limit the reactions to the appropriate electrodes. In this work, a comprehensive numerical model of the microfluidic...