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saeidian--hamdollah
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Efficient diastereo- and enantioselective synthesis of α,β-disubstituted γ-phosphono sulfonates
, Article Tetrahedron Asymmetry ; Volume 20, Issue 21 , 2009 , Pages 2429-2431 ; 09574166 (ISSN) ; Mirjafary, Z ; Saeidian, H
2009
Abstract
The first asymmetric synthesis of α,β-disubstituted γ-phosphono sulfonates is reported. The key step is the Michael addition of a lithiated enantiopure sulfonate bearing an inexpensive chiral sugar auxiliary to α,β-unsaturated phosphonates in good diastereoselectivities. After chromatographic purification, the cleavage of the chiral sugar auxiliary proceeds without any epimerization or racemization to form the corresponding isopropyl sulfonate in very good overall yield (75%) and excellent diastereomeric and enantiomeric excess (de, ee ≥ 95%). © 2009 Elsevier Ltd. All rights reserved
Synthesis of Nanoparticles and Application of the Prepared Catalyst for Some Organic Reactions, Efficient Synthesis of New Thiophene Derivatives and Asymmetric Synthesis of Sulfonic Acid Derivatives
, Ph.D. Dissertation Sharif University of Technology ; Matloubi Moghaddam, Firouz (Supervisor)
Abstract
ZnO nanopowder has been successfully synthesized by a microwave-assisted solution approach using Zn(CH3CO2)2.2H2O and NaOH. The results obtained from XRD, SEM and TEM show that the mean particle size is 30 nm. SEM and TEM micrographs of ZnO nanopowder also reveal that nanoparticles have spherical shape. A convenient one-pot multi-component reaction of aromatic aldehydes, enolizable ketones or β-keto esters and acetonitrile in the presence of acetyl chloride and 10 mol % ZnO nanoparticles for the synthesis of β-acetamido ketones/esters at room temperature is described. Catalytic activity of ZnO nanopowder for o-acylation of alcohol and phenol has also been investigated. On the other hand,...
Controlled microwave-assisted synthesis of ZnFe 2 O 4 nanoparticles and their catalytic activity for O-acylation of alcohol and phenol in acetic anhydride
, Article Scientia Iranica ; Volume 19, Issue 6 , December , 2012 , Pages 1597-1600 ; 10263098 (ISSN) ; Doulabi, M ; Saeidian, H ; Sharif University of Technology
2012
Abstract
ZnFe2O4 nanoparticles have been successfully prepared through a controlled microwave-assisted co-precipitation. X-ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FT-IR), Scanning Electron Microscopy (SEM) and Vibrating Sample Magnetometer (VSM) were used for the structural, morphological and magnetic investigation of the product. SEM micrographs of ZnFe2O4 nanopowder also reveal that nanoparticles have spherical shape. Average particle size was obtained as 12 nm from XRD. Catalytic activity of ZnFe2O4 nanopowder for O-acylation of alcohol and phenol has been investigated. A trace amount of ZnFe2O4 has been effectively used as a nanocatalyst for the acylation of alcohol and...
Microwave-assisted synthesis of 3-substituted coumarins using ZrOCl 2.8H2O as an effective catalyst
, Article Scientia Iranica ; Volume 16, Issue 1 C , 2009 , Pages 12-16 ; 10263098 (ISSN) ; Mirjafary, Z ; Saeidian, H ; Sharif University of Technology
2009
Abstract
An efficient route for the synthesis of 3-substituted coumarins via Knoevenagel condensation, using ZrOCl2.8H2O (10 mol %) as the. catalyst under microwave heating and solvent-free conditions, is described. This procedure offers several advantages, including the low loading of catalysts, high yields, clean reactions, short reaction times and the. use of various substrates, which make it a useful and attractive strategy for the. synthesis of 3-substituted coumarins. © Sharif University of Technology, June 2009
New entry to bridged pentacyclic indolyltetrahydroisoquinoline skeleton via tandem s-alkylation and intramolecular C-Alkylation
, Article Synlett ; Issue 1 , 2010 , Pages 123-127 ; 09365214 (ISSN) ; Taheri, S ; Mirjafary, Z ; Saeidian, H ; Sharif University of Technology
2010
Abstract
An efficient, single-step synthesis of hitherto unknown indole-annulated pentacyclic indolylhydroisoquinolines via tandem S-alkylation and intramolecular C-alkylation of indolin-2-thiones with N-alkylisoquinolinium salts is reported. This new approach provides a powerful entry into polycyclic structures containing nitrogen and sulfur related to alkaloids
A new trust-region method for solving systems of equalities and inequalities
, Article Computational and Applied Mathematics ; Volume 36, Issue 1 , 2017 , Pages 769-790 ; 01018205 (ISSN) ; Peyghami, M. R ; Habibi, M ; Ghasemi, S ; Sharif University of Technology
Springer Science and Business Media, LLC
2017
Abstract
In this paper, we propose a new trust-region method for solving nonlinear systems of equalities and inequalities. The algorithm combines both standard and adaptive trust-region frameworks to construct the steps of the algorithm. The trust-region subproblem is solved in the first iteration using a given initial radius. Then, in each iteration, the standard trust-region method is followed whenever the current trial step is accepted, otherwise, the subproblem is resolved using an adaptive scheme. The convergence results for the new proposed algorithm are established under some mild and standard assumptions. Numerical results on some least-squares test problems show the efficiency and...
Solvent-free synthesis of 2-amino-3-aryl-5-substituted thiophenes as anti-inflammatory agents using KF-Al2O3 under microwave irradiation
, Article Synthetic Communications ; Volume 38, Issue 12 , 2008 , Pages 2043-2053 ; 00397911 (ISSN) ; Sadeghi, A ; Mirjafary, Z ; Matloubi Moghaddam, F ; Sharif University of Technology
2008
Abstract
The synthesis of 2-amino-3-aryl-5-substituted thiophenes as anti-inflammatory agents catalyzed by KF-Al2O3 under microwave irradiation is reported. Copyright © Taylor & Francis Group, LLC
A facile aerobic copper-catalyzed α-oxygenation of aryl thioacetamides: An efficient access to α-keto aryl thioamides
, Article Synlett ; Issue 6 , 2008 , Pages 892-896 ; 09365214 (ISSN) ; Mirjafary, Z ; Saeidian, H ; Jebeli Javan, M ; Sharif University of Technology
2008
Abstract
Copper(II) efficiently catalyzes the aerobic oxidation of aryl thioacetamides into the corresponding α-keto aryl thioamides in moderate to high yields in the presence of K2CO3 under O 2 atmosphere. This protocol is simple, clean, and generates water as the only byproduct. A mechanism is proposed for the reaction course. © Georg Thieme Verlag Stuttgart
The performance of phthalimide-N-oxyl anion
, Article Monatshefte fur Chemie ; Volume 137, Issue 12 , 2006 , Pages 1591-1595 ; 00269247 (ISSN) ; Moghaddam, F. M ; Saeidian, H ; Mallakpour, S ; Sharif University of Technology
2006
Abstract
Alkali metal salts of phthalimide-N-oxyl, including Li, Na, and K were prepared and applied as novel selective catalysts to promote the cyclotrimerization of aryl and alkyl isocyanates. This paper is addressing these salts as a new class of organic nucleophilic catalysts. © Springer-Verlag 2006
Synthesis of eight-membered hydroquinolines related to alkaloid skeletons via addition of 4-hydroxycoumarin or 4-hydroxypyran-2-one to quinolinium salts
, Article Tetrahedron ; Volume 66, Issue 21 , Jan , 2010 , Pages 3678-3681 ; 00404020 (ISSN) ; Mirjafary, Z ; Saeidian, H ; Taheri, S ; Soltanzadeh, B ; Sharif University of Technology
2010
Abstract
A new one-pot synthesis of hitherto unknown polyheterocyclic systems via tandem C-alkylation and intramolecular O-alkylation of 4-hydroxycoumarin or 4-hydroxypyran-2-one with quinolinium salts in excellent yields (71-89%) is reported. The present approach provides a powerful route into polycyclic structures containing nitrogen and oxygen related to alkaloids
Facile synthesis of highly substituted 2-pyrone derivatives via a tandem Knoevenagel condensation/lactonization reaction of β-formyl-esters and 1,3-cyclohexadiones
, Article Tetrahedron Letters ; Vol. 55, issue. 18 , April , 2014 , p. 2908-2911 ; ISSN: 00404039 ; Mirjafary, Z ; Javan, M. J ; Motamen, S ; Saeidian, H ; Sharif University of Technology
2014
Abstract
A mild and efficient tandem process for the synthesis of new highly substituted 2-pyrones starting from commercially available 2-arylacetic acids has been developed. The synthesis is based on the Knoevenagel condensation of 1,3-cyclohexadiones with various β-formyl-esters, followed by lactonization in the presence of nano ZnO (20 mol %). Moderate to high yields and readily available cheap starting materials are the key features of the present method
Efficient synthesis of bicyclo[3.3.1]nonane systems via tandem 1,3-dinucleophilic addition of 4-hydroxy-2-quinolinones to quinolinium salts
, Article Synthetic Communications ; Volume 42, Issue 13 , 2012 , Pages 1941-1949 ; 00397911 (ISSN) ; Mirjafary, Z ; Saeidian, H ; Foroushani, B. K ; Nourian, S ; Sharif University of Technology
2012
Abstract
The synthesis of bicyclo[3.3.1]nonane systems is reported. The synthesis is based on the tandem 1,3-dinucleophilic addition of 4-hydroxy-2-quinolinone to quinolinium salts
A new and convenient approach to heterotetracyclic benzoxazocines through addition of 1,3-dicarbonyl compounds to quinolinium salts
, Article Tetrahedron Letters ; Volume 51, Issue 20 , April , 2010 , Pages 2704-2707 ; 00404039 (ISSN) ; Mirjafary, Z ; Saeidian, H ; Taheri, S ; Khodabakhshi, M. R ; Sharif University of Technology
2010
Abstract
The synthesis of a series of benzoxazocines has been achieved in good yields by tandem C-alkylation and intramolecular O-alkylation of 1,3-dicarbonyl compounds with quinolinium salts. This is a novel example of the synthesis of eight-membered rings via a tandem process, which provides a method for the synthesis of medium-ring heterocycles
A facile synthesis of bridged polycyclic naphthooxazocine skeletons: Eight-membered-ring constructions via tandem dinucleophilic addition of naphthalenols to quinolinium salts
, Article Helvetica Chimica Acta ; Volume 94, Issue 1 , 2011 , Pages 142-147 ; 0018019X (ISSN) ; Taheri, S ; Mirjafary, Z ; Saeidian, H ; Kiamehr, M ; Tafazzoli, M ; Sharif University of Technology
2011
Abstract
The efficient synthesis of bridged polycyclic naphthooxazocines 3 via addition of naphthalenols 1 as a bis-nucleophile to N-alkylquinolinium salts 2 is described (Scheme 1 and Table 2). This new approach provides a powerful entry into polycyclic structures containing bicyclic N,O-acetals related to bioactive compounds
Facile entry to polycyclic indolylhydroquinoline skeletons via tandem C-alkylation and intramolecular S-alkylation
, Article Tetrahedron ; Volume 66, Issue 1 , 2010 , Pages 134-138 ; 00404020 (ISSN) ; Mirjafary, Z ; Saeidian, H ; Taheri, S ; Doulabi, M ; Kiamehr, M ; Sharif University of Technology
2010
Abstract
An efficient, single step synthesis of hitherto unknown indole-annulated pentacyclic indolylhydroquinolines via tandem C-alkylation and intramolecular S-alkylation of indolin-2-thiones with N-alkylquinolinium salts in excellent yields (83-95%) is reported. This facile approach provides a powerful entry into polycyclic structures containing nitrogen and sulfur related to alkaloids. The structure of the product was determined by Röntgen crystal structure analysis
Superabsorbent polymer as nanoreactors for preparation of hematite nanoparticles and application of the prepared nanocatalyst for the friedel-crafts acylation
, Article Journal of the Brazilian Chemical Society ; Volume 20, Issue 3 , 2009 , Pages 466-471 ; 01035053 (ISSN) ; Moghaddam, F. M ; Pourjavadi, A ; Barzegar, S ; Soleyman, R ; Sohrabi, A ; Sharif University of Technology
2009
Abstract
The synthesis of pure α-Fe2O3 nanoparticles (30 nm) using a superabsorbent nanopolymer (SANP) by the thermal decomposition is reported. Synthesized α-Fe2O3 nanoparticles were characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), transmission electronic microscopy (TEM) and thermogravimetric analysis (TG) techniques. The applicability of this nanostructure material was assessed by its catalytic effect on the Friedel-Crafts acylation. ©2009 Sociedade Brasileira de Química
Efficient and green synthesis of new polycyclic procyanidin derivatives via tandem dinucleophilic addition of indolin-2-thiones to flavylium salts
, Article Pure and Applied Chemistry ; Volume 83, Issue 3 , January , 2011 , Pages 709-713 ; 00334545 (ISSN) ; Foroushani, B. K ; Saeidian, H ; Nourian, S ; Mirjafary, Z ; Kiamehr, M ; Sharif University of Technology
2011
Abstract
The green synthesis of a new series of polycyclic procyanidin derivatives has been achieved in good yields by tandem dinucleophilic addition of indolin-2-thiones to flavylium salts. The procedure is efficient and simple, and the substrates are easily available
A new domino Knoevenagel-hetero-Diels-Alder reaction: An efficient catalyst-free synthesis of novel thiochromone-annulated thiopyranocoumarin derivatives in aqueous medium
, Article Tetrahedron ; Volume 66, Issue 45 , November , 2010 , Pages 8615-8622 ; 00404020 (ISSN) ; Kiamehr, M ; Khodabakhshi, M. R ; Mirjafary, Z ; Fathi, S ; Saeidian, H ; Sharif University of Technology
2010
Abstract
An efficient catalyst-free synthesis of novel pentacyclic thiochromone-annulated thiopyranocoumarin derivatives is achieved via domino Knoevenagel-hetero-Diels-Alder reaction of 4-hydroxy dithiocoumarin and O-acrylated salicylaldehyde derivatives in H2O as solvent. The products are formed in good yields with high regio- and stereo-selectivity
Organocopper-based magnetically recoverable and reusable nanocatalyst for efficient synthesis of novel 1,2,3-triazole-based sulfonamides in green medium
, Article Research on Chemical Intermediates ; Volume 44, Issue 1 , 2018 , Pages 601-612 ; 09226168 (ISSN) ; Sadighian, H ; Arabgari, M ; Mirjafary, Z ; Ayati, S. E ; Najafi, E ; Matloubi Moghaddam, F ; Sharif University of Technology
Springer Netherlands
2018
Abstract
Abstract: We report robust green synthesis of novel 1,2,3-triazole-based sulfonamides bearing different motifs such as fluorine under click conditions in presence of a copper-based magnetically recoverable and reusable heterogeneous nanocatalyst. The organocopper catalyst at 0.5 mol.% was highly recyclable (up to five times) when recovered using an external magnet without significant loss in catalytic activity. The mild reaction conditions and excellent yields (69–95 %) make this protocol an attractive method for efficient synthesis of the title compounds. The structure of product 3a was determined by Röntgen crystal structure analysis. Graphical Abstract: [Figure not available: see...