Sharif Digital Repository

Based on the importance of DNA/RNA binding proteins in different cellular processes, finding binding sites of them play crucial role in many applications, like designing drug/vaccine, designing protein, and cancer control. Many studies target this issue and try to improve the prediction accuracy with three strategies: complex neural-network structures, various types of inputs, and ML methods to extract input features. But due to the growing volume of sequences, these methods face serious processing challenges. So, this paper presents KDeep, based on CNN-LSTM and the primary form of DNA/RNA sequences as input. As the key feature improving the prediction accuracy, we propose a new encoding... 

Entanglement spectrum is the set of eigenvalues of reduced density matrix for a definite state. It contains more information than the entanglement entropy. This spectrum can show entanglement measure, quantum phase transition and topological order in a system. In recent years, the entanglement spectrum for several models has been studied. The entanglement spectrum shows a correspondence to the energy spectrum within some specific regions, which are related to the edge state of the system; It has been verified for the Heisenberg ladder [1] and fractional quantum Hall effect [3]. Moreover, the topological order can be seen in the entanglement spectrum. There exists an acceptable adaption... 

Gesture and motion evaluation are needed for a variety of applications. The use of human hand motions as a natural interface tool has motivated researchers to conduct research in the modeling, analysis and evaluation of various hand movements. In particular, human-computer intelligent interaction has been a focus of research in vision-based gesture recognition. In this work, we introduce a 3-D hand model evaluation method that offers flexible and elaborate representation of hand motion. We used landmarked points on tips and joints of the fingers and calculated the 3-D coordinates of these points through a stereo vision system followed by an HMM (Hidden Markov Model) to recognize hand... 

International Data Company (IDC) has reported, at the end of 2020, the total amount of digital data stored in the entire world will reach 40 thousand Exabytes. The idea of accessing this volume of data, anywhere at any time by exploiting commodity hardware, led into the introduction of cloud storage. The abounded rate and variety of failures in the equipment used in cloud storage systems, placed fault tolerance, at top of the challenges in these systems. HDFS layer in Hadoop has provided cloud with reliable storage. Replication is the conventional method to protect data against failures in HDFS. But the storage overhead is a big deal and therefore designers are tending towards erasure codes.... 

Internet of Things (IoT) is a communicative infrastructure, which establishes IP-based connections between many smart devices with limited energy supplies. The gathering of such an enormous number of connected devices would impose many challenges, with routing the most important issue. Standardization of the IPv6 Routing Protocol for Low-power and Lossy Networks (RPL) was a major step towards fulfilling the IoT routing requirements. The key element in determining the routing policies and creation of the topology in RPL is the objective function. According to our studies, more than 97% of the consumed energy of a node in wireless networks is due to transceiver activities. On the other hand,... 

One of the most important concerns in food industry is decreasing the contamination of food and increasing their shelf life. Antimicrobial/antioxidant packaging, an active packaging concept, can be considered an extremely challenging technology that could have a significant impact on shelf-life extension and food safety of meat and meat products. Due to harmfulness of chemical preservatives, their use has been limited and therefore natural antimicrobial/antioxidant agents have become more popular. Propolis is a natural resinous substance, with a high polyphenol content, produced by honeybees and characterized by antimicrobial, anti-inflammatory and antioxidant properties, which make it... 

According to current researches, graphene oxide (GO) membranes show promising desalination properties due to ease of synthesis, low production cost, and high efficiency. There are several experimental works to study ionic sieving properties of GO membranes. However, it is difficult to characterize atomistic mechanism of water permeation and ion rejection by experimental approaches. On the other hand, there exist a few reports in which the atomistic picture of water permeation across GO membranes is investigated by means of molecular dynamics (MD) simulation. In the present work, in addition to water desalination, the atomic scale mechanism of ion rejection is studied using large scale MD... 

Speech synthesis and its applications have been very attractive recently. The main purpose of this technique is to produce a speech signal with natural characteristics of human speech like prosody and emotion. Among all existing methods for speech synthesis, statistical parametric speech synthesis methods are more promising because ofhigher flexibility in comparison to other methods. One of the applications of speech synthesis is speech to speech translation. In these systems, the generated voice in target language should have the same characteristics as the input voice in source language. The main purpose of this research is to review and evaluate the cross lingual speaker adaptation... 

Surface piercing propellers are particular type of supercavitating propellers that are commonly used for High-speed vessels. Most studies on this type of propellers has been investigating the hydrodynamic forces. But in recent years with increase in SPPs diameter used in vessels, structural analysis of this type of propellers is considered. For this purpose, studies on the stresses exerted on the propeller structures under load is done with the help of Hydro elastic methods. In this type of analysis, structura of propeller is intended to be flexible and Displacements under pressure checked and Tensions resulting from it are studied.
The present Thesis using ANSYS software to analyze a... 

Pricing plays an important and essential role in the profit and income of companies. The importance of pricing is not only related to its role in the company's profitability, but it also changes the customer's understanding and loyalty towards the company and can create the company's reputation or destroy it. Determining the right price will increase product sales and increase customer loyalty and create a competitive advantage for the company. One of the most important and influential variables in product pricing is the amount of demand. The main challenge of companies for product pricing is the uncertainty in their demand. In order to deal with this problem, data-driven pricing is used....