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    Hydrazine-modified starch coated magnetic nanoparticles as an effective pH-responsive nanocarrier for doxorubicin delivery

    , Article Journal of Industrial and Engineering Chemistry ; Volume 39 , 2016 , Pages 203-209 ; 1226086X (ISSN) Zohreh, N ; Hosseini, S. H ; Pourjavadi, A ; Sharif University of Technology
    Korean Society of Industrial Engineering Chemistry  2016
    Abstract
    A novel, magnetic nanocarrier was successfully synthesized through a facile and economical producer in which Fe3O4 magnetic nanoparticles were coated by starch-g-poly (methyl methacrylate-co-PEG-acrylamide). The surface of nanocarrier was then modified by hydrazine to preparation of a pH-responsive carrier. The resulted nanocarrier was applied for delivery of doxorubicin (DOX) as an effective anti-cancer drug. DOX was reacted with hydrazine linkage on the surface of nanocarrier to form hydrazone bond. Due to the presence of numerous hydrazine groups on the surface of magnetic nanocarrier large amounts of DOX was loaded onto the carrier (327 mg g−1). © 2016 The Korean Society of Industrial... 

    Cross-linked poly (dimethylaminoethyl acrylamide) coated magnetic nanoparticles: a high loaded, retrievable, and stable basic catalyst for the synthesis of benzopyranes in water

    , Article RSC Advances ; Vol. 4, issue. 91 , 2014 , p. 50047-50055 Zohreh, N ; Hosseini, S. H ; Pourjavadi, A ; Bennett, C ; Sharif University of Technology
    2014
    Abstract
    A novel heterogeneous catalyst has been synthesized based on the distillation-precipitation-polymerization of methyl acrylate onto modified magnetic nanoparticles followed by the amidation of the methyl ester groups using N,N-dimethylethylenediamine. The resulting poly(dimethylaminoethyl acrylamide) coated magnetic nanoparticles (MNP@PDMA) catalyst was characterized using an array of sophisticated analytical techniques, including FT-IR, TGA, SEM, TEM, CHN, vibrating sample magnetometer (VSM), and XRD analysis. The resulting heterogeneous base catalyst allowed the performance of a domino Knoevenagel condensation/Michael addition/cycloaddition reaction toward the synthesis of... 

    Magnetic nanoparticles entrapped in the cross-linked poly(imidazole/imidazolium) immobilized Cu(ii): An effective heterogeneous copper catalyst

    , Article RSC Advances ; Volume 4, Issue 87 , 2014 , Pages 46418-46426 ; ISSN: 20462069 Pourjavadi, A ; Hosseini, S. H ; Zohreh, N ; Bennett, C ; Sharif University of Technology
    2014
    Abstract
    Anchoring of copper sulfate in layered poly(imidazole-imidazolium) coated magnetic nanoparticles provided a highly stable, active, reusable, high loading, and green catalyst for the click synthesis of 1,2,3-triazoles via a one-pot cycloaddition of alkyl halide, azide, and alkyne (Cu-A3C). The catalyst was characterized by FTIR, TGA, TEM, SEM, XRD, EDAX, VSM and AAS. High selectivity, broad diversity of alkyl/benzyl bromide/chloride and alkyl/aryl terminal alkynes, and good to excellent yields of products were obtained using 0.7 mol% catalyst. The catalyst was readily recovered and reused up to 6 times without significant loss of activity  

    Synthesis & Properties of Nd-doped Glass-ceramics in the SiO2-CaO-MgO System from Sol-gel Method Used as Solid Lasers

    , M.Sc. Thesis Sharif University of Technology Eslami, Masoud (Author) ; Hamnabard, Zohreh (Supervisor) ; Nemati, Ali (Supervisor)
    Abstract
    In this study, SiO2-CaO-MgO galsses and glass-ceramic powder doped with Nd3+ were synthesized with sol-gel method. Tetraethylorthosilicate (TEOS), Ca(NO3)2.4H2O, Mg(NO3)2.6H2O, Nd(NO3)3.6H2O, ethanol, distilled water, and HNO3 were used as starting materials. The synthesized powder’s properties were examined with STA, XRD, DRS, PL, FTIR and SEM analysis. From XRD patterns of glass samples, the role of dopant was introduced as intermediate oxide in glass matrix. The XRD patterns of glass-ceramic samples indicated that the bredigite and akermanite crystals were formed in glass matrix. The band gap energy of samples were calculated from DRS analysis and were seen with increasing the dopant... 

    Coanda surface geometry optimization for multi-directional co-flow fluidic thrust vectoring

    , Article Proceedings of the ASME Turbo Expo: Power for Land, Sea, and Air ; Volume 5 , 2009 , Pages 183-189 ; 9780791848869 (ISBN) Saghafi, F ; Banazadeh, A ; Sharif University of Technology
    2009
    Abstract
    The performance of Co-flow fluidic thrust vectoring is a function of secondary flow characteristics and the fluidic nozzle geometry. In terms of nozzle geometry, wall shape and the secondary slot aspect ratio are the main parameters that control the vector angle. The present study aims to find a high quality wall shape to achieve the best thrust vectoring performance, which is characterized by the maximum thrust deflection angle with respect to the injected secondary air. A 3D computational fluid dynamics (CFD) model is employed to investigate the flow characteristics in thrust vectoring system. This model is validated using experimental data collected from the deflection of exhaust gases of... 

    Electrical equivalent circuit of multi-mode flexible beams with piezoelectric elements

    , Article Journal of Intelligent Material Systems and Structures ; Volume 19, Issue 5 , 2008 , Pages 621-627 ; 1045389X (ISSN) Saghafi, M ; Meghdari, A ; Sharif University of Technology
    2008
    Abstract
    Surface mounted piezoelectric sensors and actuators on elastic structures are often connected to electrical networks. The coupled equations of motion of the elastic structure with piezoelectric elements are already well known. However, due to complex behavior of some electrical elements in the electrical network, it is not an easy task to obtain the integrated equations of the whole system. A good remedy for this problem is to take advantage of an equivalent electrical circuit (EEC) representation of the mechanical part, leading the entire system to be represented as an electrical circuit. In this study, the authors propose a new method for constructing the EEC. This method is based upon the... 

    Transition flight feasibility of a fluidic thrust vectored aerial tail-sitter: Numerical approach

    , Article 2007 ASME Turbo Expo, Montreal, Que., 14 May 2007 through 17 May 2007 ; Volume 1 , 2007 , Pages 229-235 ; 079184790X (ISBN); 9780791847909 (ISBN) Saghafi, F ; Banazadeh, A ; Sharif University of Technology
    2007
    Abstract
    This paper describes a feasibility study of using numerical analysis technique, coupled with a non-linear simulation model of a conceptual fluidic-thrust-vectored unmanned aerial tailsitter to obtain required thrust deflection angles for a transition manoeuvre in take-off. It also studies the aircraft behaviour in transition subjected to the changes in specified parameters like the thrust value and the engine distance from the centre of gravity. The focus of the research presented was to get the vehicle from zero speed on the ground, in vertical position, to a specified velocity at a specified attitude, in cruise position. It was also specified that, when the vehicle was considered to be... 

    Co-flow fluidic thrust vectoring requirements for longitudinal and lateral trim purposes

    , Article AIAA/ASME/SAE/ASEE 42nd Joint Propulsion Conference, Sacramento, CA, 9 July 2006 through 12 July 2006 ; Volume 8 , 2006 , Pages 6283-6292 ; 1563478188 (ISBN); 9781563478185 (ISBN) Saghafi, F ; Banazadeh, A ; Sharif University of Technology
    2006
    Abstract
    The feasibility of using fluidic thrust-vectoring system, as a control technique for the longitudinal and lateral trim purpose was investigated in this study. For this purpose, integration of a Co-flow method into the propulsion unit of a conceptual aerial vehicle was assumed. The focus of the research presented was to estimate the required thrust vector angle in order to trim the aerial vehicle in different flight phases. Since the fluidic thrust vectoring requires secondary air flow to deflect the engine exhaust gas, this research also provides an analytical toolset for preliminary sizing of a suitable secondary air supply. It was found that thrust vectoring could be an effective mean of... 

    Dynamic stability study of a conceptual fluidic thrust-vectored aerial tail-sitter

    , Article AIAA Modeling and Simulation Technologies Conference, 2006, Keystone, CO, 21 August 2006 through 24 August 2006 ; Volume 2 , 2006 , Pages 713-724 ; 1563478218 (ISBN); 9781563478215 (ISBN) Saghafi, F ; Banazadeh, A ; Sharif University of Technology
    2006
    Abstract
    In this paper, the dynamic stability of a small thrust-vectored flapless aerial vehicle is investigated. The study was based on linearization of nonlinear equations of motion, using the aircraft longitudinal and lateral-directional stability derivatives. Since the aircraft was supposed to be merely controlled by fluidic thrust vectoring, the concept was novel and some innovative derivatives had to be introduced. The aircraft characteristic equations were then derived in terms of the obtained derivatives and used for dynamic stability analysis and flying quality assessment in horizontal flight. As well, nonlinear simulation modeling was used for dynamical mode excitation and observation. All... 

    Robust Control of Satellites Formation Flying

    , M.Sc. Thesis Sharif University of Technology Hassani, Ali (Author) ; Saghafi, Fariborz (Supervisor)
    Abstract
    Recent developments in space industry and the great tendency for definition of efficient, precise and low cost missions are the main reasons for the growing interest in satellites formation flight. Regarding the aforementioned, the study of the multiple satellite control methods is the subject of the present project. In this project, the governing equations of motion of satellite formation flight are developed. Based on this development, it is shown that the satellite linear equations of motion like many other linear system presentations, can not sufficiently model the real system. Therefore, some of the most famous uncertainties in space dynamics such as semimajor axis and eccentricity... 

    Development of a Distributed Algorithm for Flocking of Non-Holonomic Aerial Agents

    , M.Sc. Thesis Sharif University of Technology Soleymani, Touraj (Author) ; Saghafi, Fariborz (Supervisor)
    Abstract
    The goal of this project is the development of a control algorithm for a flock of non-holonomic aerial agents. For this purpose,the swarm architecture having some unique features such as robustness, flexibility, and scalability is utilized. Swarm is defined as a group of simple agents having local interactions between themselves and the environmentwhich shows an unpredictable emergent behavior.Behavior based control which is inspired from the animal behaviors is employed to control the swarm of mobile agents. Accordingly, the necessary behaviors which are distance adjustment, velocity agreement, and virtual leader tracking together with a fuzzy coordinator are designed. In this study, in... 

    Optical Flow Based Flight of a Small Fixed-Wing Aircraft in Ideal Urban Environments

    , Ph.D. Dissertation Sharif University of Technology Rezaei, Mahdi (Author) ; Saghafi, Fariborz (Supervisor)
    Abstract
    This thesis represents the obstacle avoidance of a fixed-wing small aircraft using optical flow information of cameras mounted on the aircraft. The thesis consists of two main sections. In section one, the ideal optical flow has been simulated based on the camera model, complete six DOF of flight equations, and the geometry of the environment. An analytical formula has been derived to relate the obstacle detection distance to the maneuverability of the aircraft. Having the obstacle detection distance, the control and navigation algorithms have been developed to achieve a collision-free flight for the aircraft in urban canyons and junctions. The effect of some parameters such as approach... 

    Flight Performance and Maneuverability Enhancement of a Twin Engine Fighter Aircraft Using Integrated Thrust-Vector and Aerodynamic controls

    , M.Sc. Thesis Sharif University of Technology Mazinani, Morteza (Author) ; Saghafi, Fariborz (Supervisor)
    Abstract
    In this thesis, maneuverability enhancement of a given twin engine fighter aircraft with integrated thrust-vector and conventional aerodynamic control surfaces havebeen studied. For this purpose a nonlinear 6DOF simulation program base on a near exact mathematical model has been prepared for the aircraft, and then a thrust vectoring system for producing moments about three body axes, like that used in F/A-18, has been added to the simulation. The control method that is employed to control the aircraft in simulation environment is based on Nonlinear Dynamic Inversion (NDI). Finally the Velocity Vector Roll (VVR) maneuver has been considered as an example tostudymaneuverability enhacement. It... 

    Robust Nonlinear Control of a Jet Tail-sitter UAV in Hovering Flight Phase

    , M.Sc. Thesis Sharif University of Technology Sarafraz, Yasin (Author) ; Saghafi, Fariborz (Supervisor)
    Abstract
    In this thesis, the theory of robust control is applied to design a controller for the longitudinal dynamics of a tail-sitter jet engine unmanned aerial vehicle. The engine thrust deflection is considered as the input controller of the system. The aircraft dynamical model is developed based on the assumption of no aerodynamic loads in low speed flight associated with the hovering condition. The controller is primarily designed using both classical and modern control techniques. Then and synthesis approaches are applied to design the robust controller. The results obtained from different approaches are compared. It is shown that the robust controller techniques are more stable and robust... 

    Robust Hover-flight Control Design for a Tail-sitter UAV with Ducted-fan Propulsion

    , M.Sc. Thesis Sharif University of Technology Karami, Hossein (Author) ; Saghafi, Faribourz (Supervisor)
    Abstract
    In this thesis, the theory of robust control is applied to design a controller for hover flight of a tail-sitter unmanned aerial vehicle with 2 ducted-fan propulsion. The control surface deflection (in propeller slipstream) is considered as the input controller of the system. The aircraft dynamical model is developed based on the assumption of no aerodynamic loads on other parts of uav in low speed flight associated with the hovering condition. The controller is primarily designed using both classical and modern control techniques. Then H ∞ and µ synthesis approaches are applied to design the robust controller. The results obtained from different approaches are compared. It is shown that... 

    Development of a Vision-Based Position and Attitude Estimation Algorithm for Close Proximity Operation of Small Satellite

    , M.Sc. Thesis Sharif University of Technology Pasand, Milad (Author) ; Saghafi, Fariborz (Supervisor)
    Abstract
    One of the key technologies in the future space missions is the formation flight of small satellites. Currently, widespread research in this field is being carried out and remarkable developments have been achieved. In the mentioned laboratory researches, satellite navigation is performed by conventional sensors like infrared and ultrasonic. Both of these sensors are of active type and energy consuming. Also, use of the ultrasonic sensors is impractical in space missions (due to vacuum condition). Therefore, as an alternative for space missions, visual sensors are good candidates. The main goal of this research is to present a method for the relative navigation in proximity operations in an... 

    Numerical Optimization and Parametric Study of Cooperative Salvo Attack Using Particle Swarm Optimization Algorithm

    , M.Sc. Thesis Sharif University of Technology Shahadati, Mohammad (Author) ; Saghafi, Fariborz (Supervisor)
    Abstract
    In this research work, several guidance laws have been utilized and validated, considering the contraints on the missslie seeker angle and maximum acceleration, in order to simultaneously intercept the so-called Close-in Weapon System (CIWS) by multiple missiles. First of all, the existing guidance laws for salvo-attack are reveiwed. Then, a simulation program has been developed and validated for the misslie and CIWS as a five and two degrees of freedom systems, respectively. Optimization of the system is then carried out by the method of Particle Swarm Optimization, considering the given constraints. In the next step, for the improvement of the optimized guidance law, paramertic study has... 

    Machine-Vision-Based Auotomatic Landing of Unmanned Helicopter

    , M.Sc. Thesis Sharif University of Technology Nasirian, Behnam (Author) ; Saghafi, Fariborz (Supervisor)
    Abstract
    In this project an algorithm is designed for automatic landing of unmanned helicopter on a pad moving with six degrees of freedom. The designed controller is based on state dependent riccati equations (SDRE).by developing nonlinear mathematical model of helicopter and then converting this model to state dependent coefficient (SDC) form. A nonlinear compensator is added to controller to compensate effect of some nonlinear terms of model that are not able to translate and then state dependent riccati equations are solved.
    The relative pose-estimation of landing pad is based on vision. Corner detection algorithm is used to identify and detect features by processing of image taken from... 

    Application of Nonlinear System Identification Techniques in the Modeling of Agile Fighter Aircraft Dynamics

    , Ph.D. Dissertation Sharif University of Technology Roudbari, Alireza (Author) ; Saghafi, Fariborz (Supervisor)
    Abstract
    Modeling and simulation are widely used as essential tools to predict and analyze complex systems in various scientific and engineering fields. For an aerospace system such as aircraft, mathematical models are useful used to carry out such tasks as dynamic analysis, autopilot development and combination of flight control laws, hazardous behaviors prediction, the controller design and validation, the study of the handling qualities, or the implementing simulators used for training pilots and many other tasks. In general, the aircraft flight dynamics is a nonlinear and coupled system whose dynamic modeling, in addition to pilot control inputs, depends on flight conditions (i.e., Mach and... 

    Design and Laboratory Evaluation of Slurry Seal Mixes

    , M.Sc. Thesis Sharif University of Technology Saghafi, Mahdi (Author) ; Tabatabaee, Nader (Supervisor)
    Abstract
    Pavement preventive maintenance methods such as slurry seals are cost-effective treatments that enhance pavement longevity. Incorporation of recycled materials such as reclaimed asphalt pavement (RAP) into asphalt pavements helps further reduce costs and energy consumption. Because the use of emulsions and pavement preventive methods is uncommon in Iran, there is little experience with the technology in this area. The present study designed and developed slurry seal and emulsion test devices at Sharif University lab to study the feasibility of incorporation of RAP into slurry seal mixtures while respecting the limits specified by the ISSA and ASTM. Two slurry seal mixtures in which cement...