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Mathematical Modeling and Simulation of Tumor Angiogenesis
, M.Sc. Thesis Sharif University of Technology ; Fotouhi, Morteza (Supervisor)
Abstract
A major medical revolution that is helping us overcome some of the worst diseases, including cancer, is angiogenesis, which is based on the processes our bodies use to develop blood vessels. Most human cancers have acquired six essential capabilities: self-sufficiency in growth signals, insensitivity to growth-inhibitory signals, programmed cell death escape, unlimited replication potential, persistent angiogenesis, and tissue invasion that can induce metastasis. In other words, the defense mechanism that prevents any of these acquired capabilities must be neutralized before the cells become malignant and invasive tumors. In fact, tumors in the non-vascular growth stage can only grow up to...
Network Analysis of EEG Data of Alzheimer’s Disease
, M.Sc. Thesis Sharif University of Technology ; Jalili, Mahdi (Supervisor)
Abstract
Recently complex networks, have been widely used as a model to study the behavior of human brain. By affecting different parts the brain, Neuronal disorders change the structure of functional brain networks. Investigating these changes using different graph theory metrics can be a useful methodology for human brain analysis in health and disease. Alzheimer's disease (AD) is a neural disease causing impairment in different brain activities including memory and cognition.The aim of this study is to construct the functional brain network of 17 AD patients and 17 healthy control subjects at resting state condition and analyzing them using the theory of complex networks in order to achieve a...
Driving of Quantum Hamiltonian Relative to The One Dimentional Cavity With Oscilating Mirror and Semi-Transparent Mirror
, M.Sc. Thesis Sharif University of Technology ; Bahrampour, Alireza (Supervisor)
Abstract
The concept of entanglement exists in the common area of the quantum optics and quantum information. Quantum optics is the best tools for investigating of this quantum informational phenomenon experimentally. One of the instruments that let us observes experimentally macroscopy entangeled state is Fabry-Perot Cavity. Striking of photons with the mirror of cavity transfer effective mommentom to it, and oscilating of mirror creates new modes: stocks and anti-stocks modes. Studing quantum state of these modes shows the entangling between photon and phonon (oscilating of mirror) modes. We assume that light beam enters the cavity from a semi-transparent mirror. So cavity is the system with...
Qualitative Study of the Dynamic Adsorption Layer by Bubble Rising Method
, M.Sc. Thesis Sharif University of Technology ; Bastani, Dariush (Supervisor) ; Lotfi, marzieh (Co-Advisor)
Abstract
Surface phenomena and dynamic interfacial properties plays a significant role in multiphase gas-liquid & liquid-liquid processes applied in different industrial applications. However, current laboratory equipment and represented methods for dynamic and unsteady state condition caused by motivation of interface of two phases (like rising bubble), in purpose of qualitative investigation of interphase properties are not satisfying enough. Also, common modeling methods are represented with lots of modified assumptions which are not validated properly with experimental results. In current thesis, with development of laboratory tools and applying the “rising bubble method” for investigating the...
Non-Equilibrium Interfacial Behavior of Dynamic Interfaces in Presence of Surfactants and Nanoparticles; Experimental and Computational Fluid Dynamic Investigations
, Ph.D. Dissertation Sharif University of Technology ; Bastani, Dariush (Supervisor) ; Lotfi, Marzieh (Supervisor)
Abstract
The present study has been performed for better understanding about the dynamic behavior of fluid interfaces in presence of surfactants, nanoparticles and their interactions in gas-liquid dispersion systems. One of the main purposes of this work is to investigate the influence of surface modified nanoparticles on the dynamic behavior of gas-liquid interfaces. For this purpose, the rising bubble experiment was used as one of the most conventional procedures. Local velocities of bubbles rising in nanoparticle solutions were determined experimentally. Influences of silica nanoparticles which were modified via three approaches were investigated in these experiments. Heat treatment was applied to...
Global Control of Hybrid Microgrids Using MIMO Control
, M.Sc. Thesis Sharif University of Technology ; Mokhtari, Hossein (Supervisor)
Abstract
Given the growing advantage of exploiting renewable energy resources over fossil fuels and using distributed generation systems, microgrids seem to be the best solution for reaching the energy-efficient world of the future. Hybrid microgrids are the best options among all other types of microgrids because they make it possible to use AC and DC sources and loads together and at the same time. Since connecting AC and DC sections of a hybrid microgrid leads to the interaction between them, proper control of interlinking converter(s) is crucial for the reliable and stable operation of the entire microgrid. In this study, small signal model of a hybrid AC/DC microgrid consisting of static and...
Investigation of the Liquid Viscosity Effect on the Rising Bubble Motion (Effect of Ethylene Glycol Concentration on Terminal Velocity)
, M.Sc. Thesis Sharif University of Technology ; Bastani, Dariush (Supervisor) ; Lotfi, Marzieh (Co-Advisor)
Abstract
Surface phenomena is one of the fundamental branches of science that has many applications in industries related to multiphase processes. One of the most important issues of this knowledge is inter-phase transport phenomena in contacting gas - liquid and liquid – liquid systems. Multiphase systems generally include dispersions such that in many cases are associated with the relative motion between the continuous and dispersed phase. One of the most widely used inter-phase flow systems is dispersion of gas bubbles in the bulk of liquid. The overall efficiency of these systems is often determined by the characteristics of the gas phase. In order to understand the dynamic behavior of such...
Theoretical Investigation of Quantum Optical Amplifiers in Quantum Communications
, M.Sc. Thesis Sharif University of Technology ; Bahrampour, Alireza (Supervisor) ; Bathaee, Marzieh Sadat (Co-Supervisor)
Abstract
Signal transmission of information on noiseless and lossy channels is an important issue in data transmission. Using the amplifier in the transmission channels is a good solution to help send information on longer channels. In classical communication, information can be coded in the amplitude or phase of the field and an amplifier is responsible for amplifying these parameters. If we consider the conditions ideal and ignore electrical noises, Classical mechanics does not impose any restrictions on the amplification of arbitrary classical signals. Instead, in quantum telecommunications the information encoded on the quadrature of the electromagnetic field are mounted on quantum states, such...
Incorporating Degree of Belief, Desire and Capability into Propositional Belief Desire and Intention Logic
, M.Sc. Thesis Sharif University of Technology ; Ardeshir, Mohammad (Supervisor)
Abstract
Nowadays, BDI architecture is of the most well known agent’s architectures. BDI architecture or the architecture in which the system is viewed as rational agents based on the attitudes of belief, desire and intention represents an abstraction of human deliberation based on a theory of rational action in the human cognition process. BDI logic introduced by Rao and Georgeff have been widely used as the theoretical basis of specification and implementation of rational agents. BDI logic is limited to deal with crisp assertion, while the assertions encountered in real world are not precise and thus cannot be treated simply by using yes or no. Moreover, In order to obtain more human like agents we...
Synthesis of Novel Biodegradable Collagen-Based Superabsorbent Hydrogels and Investigation of their Swelling Behavior in Various Media
, Ph.D. Dissertation Sharif University of Technology ; Pourjavadi, Ali (Supervisor)
Abstract
The use of super-swelling polymers is steadily increasing and the applications in industry are continuing to grow. With the authorization of the superabsorbents in food packaging by the Food and Drug Administration recently, demand may soon take off in the market. The worldwide production of SAPs is more than one million tons per year, representing a multibillion-dollar market. However, the increase in prices of petroleum products in recent years may be a drawback for these acrylic-based materials. Thus, there is now a need to develop natural-based super-swelling hydrogels which are more economical and environment friendly. In addition, the super-swelling gels are promising novel functions...
Activity-based Travel Demand Modeling in Rural Areas; Case Study of Villages Far-from-city in Fars Province
, M.Sc. Thesis Sharif University of Technology ; Vaziri, Manouchehr (Supervisor)
Abstract
Although rural inhabitants constitute a large portion of developing countries’ population, they have always been neglected in many ways. Expansion of equity, calls for a new concern in adequacy of rural development. The problem could be considered in two aspects: Firstly, there is a great tendency for immigration to nearby cities, hoping for a better life. This would result in more crowded cities, extended poverty and an increasing rate of crime mainly in suburban areas. On the other hand, the evacuation of farms and fertilized lands imposes great economical loss to the country. Therefore, development of rural facilities should be integrated into national policies to assure a homogeneous and...
Development of Airport Capacity Management Model Based on Decision Support System
, M.Sc. Thesis Sharif University of Technology ; Pourtakdoust, Hossein (Supervisor)
Abstract
Airports are one of the most important elements of the aviation system that provide the ground infrastructure that is required for enabling or flight across the globe. Master Planning is currently the dominant approach to airport strategic planning. However, history shows that this approach can often result in costly mistakes. Because there are many stakeholders with conflicting objectives, deep uncertainty about the future, and many potential strategies, planners often narrow their scope by using a single forecast for the future, leaving out alternative strategies, and excluding stakeholders, resulting in a Master Plan that quickly becomes obsolete and may be opposed by some stakeholders....
VulSlicer: Vulnerability detection through code slicing
, Article Journal of Systems and Software ; Volume 193 , 2022 ; 01641212 (ISSN) ; Kharrazi, M ; Sharif University of Technology
Elsevier Inc
2022
Abstract
There has been a multitude of techniques proposed for identifying vulnerabilities in software. Forcing a program into a vulnerable state has become increasingly unscalable, given the size of the programs and the number of possible execution states. At the same time, techniques that are looking for vulnerability signatures are marred with weak and incomplete signatures. This is not to say that such techniques have failed to identify previously unknown vulnerabilities in the code. However, they have inherent weaknesses, which result in identifying vulnerabilities that are limited in type and complexity. We propose a novel technique to extract succinct vulnerability-relevant statements...
Vulnerability Extraction in Large Codebases Through Template Generalization
, Ph.D. Dissertation Sharif University of Technology ; Kharrazi, Mehdi (Supervisor)
Abstract
As the size and complexity of software increase, the number of software vulnerabilities also increases. An examination of vulnerability reports shows that in addition to the fact that a large number of unknown vulnerabilities still exist in software, there is still no proper solution for identifying vulnerabilities that have been observed one sample of them exit in real-world software. The main reason for such an event is the lack of a suitable template for recognized vulnerabilities, which ultimately makes searching for them in other software a problem of scalability and high search cost. This thesis, recognizing the importance of the issue, presents a framework for extracting robust and...
The olfactory bulb modulates entorhinal cortex oscillations during spatial working memory
, Article Journal of Physiological Sciences ; Volume 71, Issue 1 , 2021 ; 18806546 (ISSN) ; Tabasi, F ; Nazari, M ; Ghazvineh, S ; Salimi, A ; Jamaati, H ; Raoufy, M. R ; Sharif University of Technology
BioMed Central Ltd
2021
Abstract
Cognitive functions such as working memory require integrated activity among different brain regions. Notably, entorhinal cortex (EC) activity is associated with the successful working memory task. Olfactory bulb (OB) oscillations are known as rhythms that modulate rhythmic activity in widespread brain regions during cognitive tasks. Since the OB is structurally connected to the EC, we hypothesized that OB could modulate EC activity during working memory performance. Herein, we explored OB–EC functional connectivity during spatial working memory performance by simultaneous recording local field potentials when rats performed a Y-maze task. Our results showed that the coherence of delta,...
Evaluation of Exerted Drag Force on Alkane Saturated Air Bubbles in Aqueous Solutions by Experimental Studies
, M.Sc. Thesis Sharif University of Technology ; Bastani, Dariush (Supervisor) ; Lotfi, Marzieh (Supervisor)
Abstract
Interfacial phenomena and properties of interphase surfaces in dynamic mode play an important role in industrial processes that include gas-liquid and liquid-liquid multiphase flows. As well as, interface knowledge leads to better understanding of natural and fundamental phenomena. The present study has been performed for understanding about dynamic behavior of interphase surfaces in the presence of nanoparticles and hexane vapor in gas-liquid dispersion systems. In this research, rising bubble method has been used as one of the most conventional techniques. Accordingly, aqueous solutions of nanosilica were prepared in concentrations of 50, 100, 200, 400 and 1200 ppm as continuous phase...
Application of Cellulose Nanofibers Coated Quartz Crystal Microbalance (QCM) Biosensor for Amino Acid Detection in Aqueous Media
, Ph.D. Dissertation Sharif University of Technology ; Irajizad, Azam (Supervisor) ; Vossoughi, Manouchehr (Supervisor)
Abstract
Developing a simple, cost effective and accurate detection method for L-lysine (Lys), L-leucine (Leu) and glycine (Gly) as the important analytes in clinical diagnostics, biological processes and food industries is of great interest. Therefore, in the first part of this research, cellulose nanofibrils (CNFs) were coated on a quartz crystal microbalance (QCM) surface by spin coating to achieve a QCM biodetector for Gly. Thus, the two-layer CNFs coating was selected as sensing film and was applied for following experiments. In the next step, the coated QCMs were carefully characterized before and after interaction with Gly using water contact angle (WCA), Fourier transform infrared...
PMU Based Fault Location on Transmission Lines
, M.Sc. Thesis Sharif University of Technology ; Ranjbar, Alimohammad (Supervisor)
Abstract
One of the most essential part of power system are transmission lines. Transmission of power from production centers to consumption centers is duty of these lines. Any disturbance in this duty make great losses to producers and consumers. One of the most disturbance in transmission lines are short circuits that occurred because of various causes. Most faults on transmission lines occurred in stormy weather that make more troubles for fault search. So we need a tool that can find location of fault precisely and quickly. This tool named fault locator. There are many algorithms for fault location and detection on power system transmission lines. These algorithms usually are dependent on very...
Hazard Identification by HAZOP Method and Risk Assessment Based on Fuzzy Logic with Case Study
, M.Sc. Thesis Sharif University of Technology ; Rashtchian, Davood (Supervisor)
Abstract
According to privileged risks existing in process industries and intensity of their consequences, Safety investigation and risk assessment are highly significant in these unites. Execution of risk assessment in process unites has been constituted from two qualitative and quantitative parts. The most crucial issue in risk assessment procedure is uncertainties related to data and needed information, besides of various models presented. This subject frequently relates to deficiency, ambiguity, and inaccessibility of necessary information for specifying of risk assessment characteristics i.e., event reproducibility and their intensities. In this work for overcome these constraints, bow-tie fuzzy...
Adaptive control of robot manipulators including actuator dynamics and without joint torque measurement
, Article 2010 IEEE International Conference on Robotics and Automation, ICRA 2010, Anchorage, AK, 3 May 2010 through 7 May 2010 ; 2010 , Pages 4639-4644 ; 10504729 (ISSN) ; 9781424450381 (ISBN) ; Namvar, M ; Sharif University of Technology
2010
Abstract
Ignoring actuator dynamics in control of rigid manipulators can in practice result in performance degradation or loss of system stability. However, consideration of actuator dynamics usually requires measurement of robot joint torques. This paper addresses motion tracking control of an n-DOF rigid robot by taking into account its actuator dynamics. Joint torque measurement is avoided by using an adaptive observer. The backstepping technique is adopted to develop a dynamically smooth adaptive nonlinear controller dealing with uncertainties in manipulator and actuator dynamics. Semi-global convergence of motion tracking errors as well as torque estimation error are proven without any...