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    Synthesis and characterization of magnetic hybrid nanomaterials via RAFT polymerization: A pH sensitive drug delivery system

    , Article Colloids and Surfaces B: Biointerfaces ; Volume 174 , 2019 , Pages 153-160 ; 09277765 (ISSN) Pourjavadi, A ; Kohestanian, M ; Shirzad, M ; Sharif University of Technology
    Elsevier B.V  2019
    Abstract
    Herein, a facile and versatile method for the synthesis of a novel magnetic nanocarrier via surface- initiated reversible addition-fragmentation chain transfer (RAFT) polymerization is introduced. At first, RAFT agent was successfully attached to the surface of Fe 3 O 4 nanoparticles and, then, poly (glycidyl methacrylate) (PGMA) chains were grown and anchored onto the surface of Fe 3 O 4 nanoparticles. At the end, hydrazine (Hy) groups were introduced to the PGMA chains via reaction between epoxy rings and hydrazine molecules. Doxorubicin (DOX) was covalently conjugated to the prepared nanocarrier (Fe 3 O 4 @PGMA@Hy) through a hydrazone linkage. The in vitro drug release of Fe 3 O 4... 

    Truthful Routing in Mobile Ad Hoc Networks

    , M.Sc. Thesis Sharif University of Technology Shirzad, Fatemeh (Author) ; Movaghar, Ali (Supervisor)
    Abstract
    In Mobile Ad hoc Networks (MANETs), nodes depend on each other for routing and forwarding their packets. However, to save power and other resources, nodes belonging to independent authorities may behave selfishly, and not cooperate in network activities. Such selfish behaviour poses a real threat to the proper functioning of MANETs. To cope with this situation, a motivation stimulation mechanism is required to provide sufficient incentives for nodes to forward other nodes’ packets. One Appropriate approach is to have network nodes paid in order to motivate them to cooperate with protocol. To achieve truthfulness, the payment based on the cost of transmission of packets. Since the mentioned... 

    Designing a Succinct Argument System Based on GKR Protocol Via Polynomial Commitment Schemes

    , M.Sc. Thesis Sharif University of Technology Shirzad, Alireza (Author) ; Eghlidos, Taraneh (Supervisor)
    Abstract
    With the dramatic advancements in information technology and the industry requirements for security and privacy, proof systems play a crucial role in cryptography. Among the vast variety of proof systems, succinct non-interactive arguments (SNARG) seem to be the most appealing class of proof systems, due to their attractive properties. SNARGs are usually made up of two constructive components, namely the information theoretic part and the cryptographic part. The GKR protocol was introduced as a proof system for a tractable family of languages called “log-Space Uniform Circuits”. The log-space uniformity is a necessary condition for the protocol to be succinct. Hence, it is not possible to... 

    Designing a Succinct Argument System Based on GKR Protocol Via Polynomial Commitment Schemes

    , M.Sc. Thesis Sharif University of Technology Shirzad, Alireza (Author) ; Eghlidos, Taraneh (Supervisor)
    Abstract
    With the dramatic advancements in information technology and the industry requirements for security and privacy, proof systems play a crucial role in cryptography. Among the vast variety of proof systems, succinct non-interactive arguments (SNARG) seem to be the most appealing class of proof systems, due to their attractive properties. SNARGs are usually made up of two constructive components, namely the information theoretic part and the cryptographic part. The GKR protocol was introduced as a proof system for a tractable family of languages called “log-Space Uniform Circuits”. The log-space uniformity is a necessary condition for the protocol to be succinct. Hence, it is not possible to... 

    Bayesian identification of soil-foundation stiffness of building structures

    , Article Structural Control and Health Monitoring ; Volume 25, Issue 3 , 2018 ; 15452255 (ISSN) Shirzad Ghaleroudkhani, N ; Mahsuli, M ; Ghahari, F ; Taciroglu, E ; Sharif University of Technology
    John Wiley and Sons Ltd  2018
    Abstract
    A probabilistic method is presented for identifying the dynamic soil-foundation stiffnesses of building structures. It is based on model updating of a Timoshenko beam resting on sway and rocking springs, which respectively represent the superstructure and the soil-foundation system. Unlike those previously employed for this particular problem, the proposed method is a Bayesian one, which accounts for the prevailing uncertainties due to modeling and measurement errors. As such, it yields the probability distribution of the system parameters as opposed to average/deterministic values. In this approach, the joint probability density function of the parameters that control the flexible-base... 

    A distributed truthful routing protocol for mobile ad hoc networks

    , Article Proceedings of ICCIA 2010 - 2010 International Conference on Computer and Information Application, 2 November 2010 through 4 November 2010, Tianjin ; 2010 , Pages 133-140 ; 9781424485963 (ISBN) Shirzad, F ; Movaghar, A ; Shirzadeh, E ; Sharif University of Technology
    2010
    Abstract
    In Mobile Ad hoc Networks (MANETs), nodes depend on each other for routing and forwarding their packets. However, to save power and other resources, nodes belonging to independent authorities may behave selfishly, and not cooperate in network activities. Such selfish behaviour poses a real threat to the proper functioning of MANETs. To cope with this situation, a motivation stimulation mechanism is required to provide sufficient incentives for nodes to forward other nodes' packets. One appropriate approach is to have network nodes pay in order to motivate them to cooperate with the protocol. To achieve truthfulness, the payment should be based on the cost of transmission of packets. Since... 

    ”A Study on the Process of Passive Uptake of Nanoparticles by Coarse-Grained MD Simulation”

    , M.Sc. Thesis Sharif University of Technology Shirzad, Hoda (Author) ; Ejtehadi, Mohammad Reza (Supervisor)
    Abstract
    The aim of this thesis is to investigate the passive wrapping of nanoparticles by a lipid membrane in the uptake process using molecular dynamics computer simulations. The simulations are carried out by the Virtual Cell Model (VCM) software package, a computational framework that creates a large scale coarse-grained multi-component cell model developed by Prof Mohammad Reza Ejtehadi’s Soft Matter Group at Sharif University of Technology. VCM can model the dynamics of different parts of the cell and investigate their mechanical properties.A chapter of this thesis contributes to further development of the membrane model used in the VCM to simulate nanoparticles interactions with a membrane.... 

    The impact of religiosity on the disability, psychological well-being, and somatic health of multiple sclerosis patients

    , Article Mental Health, Religion and Culture ; Volume 25, Issue 5 , 2022 , Pages 519-530 ; 13674676 (ISSN) Mohaghegh, F ; Eslami, M ; Dadfar, M ; Lester, D ; Ayten, A ; Rashidizadeh, A ; Shirzad, F ; Sharif University of Technology
    Routledge  2022
    Abstract
    The aim of the study was to predict disability, psychological wellbeing, and somatic health in multiple sclerosis (MS) patients with the mediating variable of religiosity. A sample of 128 patients was recruited, and were administered the Expanded Disability Status Scale, the World Health Organization-5 Well-Being Index, the Patient Health Questionnaire-15, and a Self-Rating Scale of Religiosity. Religiosity did not predict disability, psychological well-being, or somatic health. Religiosity was positively associated with MS duration and disability, but only in male patients. The predictors for predicting psychological wellbeing were age, disability, and somatic health. Patients with... 

    Bayesian Identification of Soil-foundation Stiffness Using a Timoshenko Beam Model

    , M.Sc. Thesis Sharif University of Technology Shirzad Ghaleroodkhani, Nima (Author) ; Mahsuli, Mojtaba (Supervisor)
    Abstract
    A probabilistic method is presented for identifying the dynamic soil-foundation stiffnesses of building structures. It is based on model updating of a Timoshenko beam resting on sway and rocking springs, which respectively represent the superstructure and the soil-foundation system. Unlike those previously employed for this particular problem, the proposed method is a Bayesian one, which accounts for the prevailing uncertainties due to modeling and measurement errors. As such, it yields the probability distribution of the system parameters as opposed to average/deterministic values. In this approach, the joint probability density function of the parameters that control the flexible-base... 

    The role of polyethylene glycol size in chemical spectra, cytotoxicity, and release of pegylated nanoliposomal cisplatin

    , Article Assay and Drug Development Technologies ; Volume 17, Issue 5 , 2019 , Pages 231-239 ; 1540658X (ISSN) Shirzad, M ; Jamehbozorgi, S ; Akbarzadeh, I ; Aghabozorg, H. R ; Amini, A ; Sharif University of Technology
    Mary Ann Liebert Inc  2019
    Abstract
    This study aimed to synthesize methoxy polyethylene glycol propionaldehyde (mPEG20,000-ALD) for the preparation of PEGylated nanoliposomal cisplatin. Nanocarriers such as liposomes are developed for a wide range of drug delivery systems. PEG with high molecular weight (Mw) is used to coat the liposomes. In this study, simulated Fourier transform infrared (FTIR) spectra of mPEG-ALD were obtained using density functional theory (DFT) calculations and then compared with actual FTIR spectrum of mPEG20,000-ALD (Mw = 20 kDa). We found that the intensity of C = O stretching vibration at 1,700 cm-1 related to the carbonyl functional group of mPEG20,000-ALD was very weak. The results of DFT... 

    Metabolic load comparison between the quarters of a game in elite male basketball players using sport metabolomics

    , Article European Journal of Sport Science ; 2020 Khoramipour, K ; Gaeini, A. A ; Shirzad, E ; Gilany, K ; Chashniam, S ; Sandbakk, Ø ; Sharif University of Technology
    Taylor and Francis Ltd  2020
    Abstract
    Purpose: A basketball match is characterized by intermittent high-intensity activities, thereby relying extensively on both aerobic and anaerobic metabolic pathways. Here, we aimed to compare the metabolic fluctuations between the four 10-min quarters of high-level basketball games using metabolomics analyses. Methods: 70 male basketball players with at least 3 years of experience in the Iran national top-league participated. Before and after each quarter, saliva samples were taken for subsequent untargeted metabolomics analyses, where Principal component analysis (PCA) and Partial least squares-discriminant analysis (PLS-DA) were employed for statistical analysis. Results: Quarters 1 and 3... 

    Metabolic load comparison between the quarters of a game in elite male basketball players using sport metabolomics

    , Article European Journal of Sport Science ; Volume 21, Issue 7 , 2021 , Pages 1022-1034 ; 17461391 (ISSN) Khoramipour, K ; Gaeini, A. A ; Shirzad, E ; Gilany, K ; Chashniam, S ; Sandbakk, Ø ; Sharif University of Technology
    Taylor and Francis Ltd  2021
    Abstract
    Purpose: A basketball match is characterized by intermittent high-intensity activities, thereby relying extensively on both aerobic and anaerobic metabolic pathways. Here, we aimed to compare the metabolic fluctuations between the four 10-min quarters of high-level basketball games using metabolomics analyses. Methods: 70 male basketball players with at least 3 years of experience in the Iran national top-league participated. Before and after each quarter, saliva samples were taken for subsequent untargeted metabolomics analyses, where Principal component analysis (PCA) and Partial least squares-discriminant analysis (PLS-DA) were employed for statistical analysis. Results: Quarters 1 and 3... 

    Probability of missed detection as a criterion for receiver placement in MIMO PCL

    , Article IEEE National Radar Conference - Proceedings, 7 May 2012 through 11 May 2012, Atlanta, GA ; 2012 , Pages 0924-0927 ; 10975659 (ISSN) ; 9781467306584 (ISBN) Majd, M. N ; Chitgarha, M. M ; Radmard, M ; Nayebi, M. M ; Sharif University of Technology
    IEEE  2012
    Abstract
    Using multiple antennas at the transmit and receive sides of a passive radar brings both the benefits of MIMO radar and passive radar. However one of the obstacles arisen in such configuration is the receive antennas placement in proper positions so that the radar performance is improved. Here we just consider the case of positioning one receiver among multiple illuminators of opportunity. Indeed it is a start for the solution of optimizing the geometry of the multiple receivers in a passive radar  

    An efficient method for the ring opening of epoxides with aromatic amines by Sb(III) chloride under microwave irradiation

    , Article Journal of Chemical Research ; Issue 4 , 2008 , Pages 220-221 ; 03082342 (ISSN) Ghazanfari, D ; Hashemi, M. M ; Mottaghi, M. M ; Foroughi, M. M ; Sharif University of Technology
    2008
    Abstract
    SbCl3 supported on montmorillonite K-10 is an efficient catalyst for the ring opening of epoxides with aromatic amines under solvent-free conditions and microwave irradiation to give the corresponding b-amino alcohols in high yields with high regioselectivity  

    Resource allocation for uav-enabled integrated sensing and communication (isac) via multi-objective optimization

    , Article ICASSP, IEEE International Conference on Acoustics, Speech and Signal Processing - Proceedings ; Volume 2023-June , 2023 ; 15206149 (ISSN); 978-172816327-7 (ISBN) Rezaei, O ; Naghsh, M. M ; Karbasi, M ; Nayebi, M. M ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2023
    Abstract
    In this paper, we consider an integrated sensing and communication (ISAC) system with wireless power transfer (WPT) where an unmanned aerial vehicle (UAV)-based radar serves a group of energy-limited communication users in addition to its sensing functionality. In this architecture, the radar senses the environment in phase 1 (namely sensing phase) and mean-while, the communications users (nodes) harvest and store the energy from the radar transmit signal. The stored energy is then used for information transmission from the nodes to UAV in phase 2, i.e., uplink phase. Performance of the radar system depends on the transmit signal as well as the receive filter; the energy of the transmit... 

    MIMO radar signal design to improve the MIMO ambiguity function via maximizing its peak

    , Article Signal Processing ; Volume 118 , 2016 , Pages 139-152 ; 01651684 (ISSN) Chitgarha, M. M ; Radmard, M ; Nazari Majd, M ; Karbasi, S. M ; Nayebi, M. M ; Sharif University of Technology
    Elsevier  2016
    Abstract
    One of the important obstacles in MIMO (Multiple Input Multiple Output) radars is the issue of designing proper transmit signals. Indeed, the capability of signal design is a significant advantage in MIMO radars, through which, the system can achieve much better performance. Many different aspects of this performance improvement have been considered yet, and the transmit signals have been designed to attain such goal, e.g., getting higher SNR or better detector's performance at the receiver. However, an important tool for evaluating the radar's performance is its ambiguity function. In this paper, we consider the problem of transmit signal design, in order to optimize the ambiguity function... 

    Detection-localization tradeoff in MIMO radars

    , Article Radioengineering ; Volume 26, Issue 2 , 2017 , Pages 581-587 ; 12102512 (ISSN) Nazari Majd, M ; Radmard, M ; Chitgarha, M. M ; Bastani, M. H ; Nayebi, M. M ; Sharif University of Technology
    2017
    Abstract
    Two gains play key roles in recently developed MIMO wireless communication systems: "spatial diversity" gain and "spatial multiplexing" gain. The diversity gain refers to the capability to decrease the error rate of the MIMO channel, while the multiplexing gain implicitly refers to the amount of increase in the capacity of the MIMO channel. It has been shown that there is a fundamental tradeoff between these two types of gains, meaning interplay between increasing reliability (via an increase in the diversity gain) and increasing data rate (via an increase in the multiplexing gain). On the other hand, recently, MIMO radars have attracted much attention for their superior ability to enhance... 

    Antenna placement and power allocation optimization in MIMO detection

    , Article IEEE Transactions on Aerospace and Electronic Systems ; Vol. 50, Issue 2 , April , 2014 , pp. 1468-1478 Radmard, M ; Chitgarha, M. M ; Majd, M. N ; Nayebi, M. M ; Sharif University of Technology
    2014
    Abstract
    It is a well known fact that using multiple antennas at transmit and receive sides improves the detection performance. However, in such multiple-input multiple-output (MIMO) configuration, proper positioning of transmitters and receivers is a big challenge that can have significant influence on the performance of the overall system. In addition, determining the power of each transmitter under a total power constraint is a problem that should be solved in order to enhance the performance and coverage of such a system. In this paper, we design the Neyman-Pearson detector under the Rayleigh scatter model and use it to introduce a criterion for the antenna placement at both transmit and receive... 

    Ambiguity function of MIMO radar with widely separated antennas

    , Article Proceedings International Radar Symposium ; 16 -18 June , 2014 ; ISSN: 21555753 Radmard, M ; Chitgarha, M. M ; Nazari Majd, M ; Nayebi, M. M ; Sharif University of Technology
    2014
    Abstract
    There has been much interest, recently, towards exploiting the Multiple-Input Multiple-Output (MIMO) technique in radar. It is shown that using multiple antennas at transmit and receive sides can improve the performance of the system. However, in order to analyze the system's performance, its ambiguity function, i.e. the ambiguity function of a MIMO radar, is needed to be defined. In this paper, beginning from the information theoretic definitions, we derive such function, specifically for a MIMO radar with widely separated antennas  

    Choosing the position of the receiver in a MISO passive radar system

    , Article European Microwave Week 2012: "Space for Microwaves", EuMW 2012, Conference Proceedings - 9th European Radar Conference, EuRAD 2012 ; 2012 , Pages 318-321 ; 9782874870293 (ISBN) Chitgarha, M. M ; Majd, M. N ; Radmard, M ; Nayebi, M. M ; Sharif University of Technology
    2012
    Abstract
    By combining the two ideas of MIMO (Multiple Input Multiple Output) and PCL (Passive Coherent Location) in radar, one can achieve the advantages of both recently developed techniques simultaneously. While using multiple antennas at the receive side provides a spatial diversity of the object to be detected, using multiple illuminators of opportunity, most importantly, makes the radar covert to the interceptors. One obstacle in such MIMO configuration is choosing the positions of the receive antennas. In this paper, after analyzing the Neyman-Pearson detector for the DVB-T based PCL, we introduce the probability of missed detection as a criterion to place the receive antenna. Here, we only...