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Alginate/cartilage extracellular matrix-based injectable interpenetrating polymer network hydrogel for cartilage tissue engineering
, Article Journal of Biomaterials Applications ; Volume 36, Issue 5 , 2021 , Pages 803-817 ; 08853282 (ISSN) ; Mashayekhan, S ; Pazooki, H ; Mohsenifard, S ; Baniasadi, H ; Sharif University of Technology
SAGE Publications Ltd
2021
Abstract
In the present study, alginate/cartilage extracellular matrix (ECM)-based injectable hydrogel was developed incorporated with silk fibroin nanofibers (SFN) for cartilage tissue engineering. The in situ forming hydrogels were composed of different ionic crosslinked alginate concentrations with 1% w/v enzymatically crosslinked phenolized cartilage ECM, resulting in an interpenetrating polymer network (IPN). The response surface methodology (RSM) approach was applied to optimize IPN hydrogel's mechanical properties by varying alginate and SFN concentrations. The results demonstrated that upon increasing the alginate concentration, the compression modulus improved. The SFN concentration was...
Assessment of Existing Offshore Platforms for In-Place Conditions
, M.Sc. Thesis Sharif University of Technology ; Golafshani, Ali Akbar (Supervisor)
Abstract
Assessment of existing jacket type offshore platforms in Persian Gulf for life extension is of great importance in the field of offshore platforms in recent years. The main question to answer is whether an existing platform is safe enough to be used beyond the design life. Evaluation of existing jacket type offshore platforms under extreme environmental (wave) loading in Persian Gulf is a part of this major assessment. Two general approaches exist in this context, deterministic and probabilistic assessment. In this thesis, a new probabilistic method (reliability analysis) to assess offshore structures under environmental loading (extreme wave) is introduced. This method is a...
Fabrication of in Situ Forming Hydrogels Composed of Acellular Cartilage Matrix with Improved Mechanical Properties for Recovery of Local Damages in Articular Cartilage
, M.Sc. Thesis Sharif University of Technology ; Mashayekhan, Shohreh (Supervisor) ; Hassanzadeh, Zabihollah (Co-Supervisor)
Abstract
Since cartilage has limited self-regeneration, in-situ forming hydrogels can act as an ideal scaffold for cartilage tissue engineering to fill the defect gap due to their ability to homogeneously encapsulate the desired cells, efficient mass transfer and minimally invasive characteristics. In this project, an injectable hydrogel with improved structure by adding silk fibroin (SF) nanofibers and better biochemical properties by employing the cartilage extracellular matrix (ECM) was fabricated. The in-situ forming hydrogel is consisted of different concentrations of ionic crosslinked alginate incorporated with different concentrations of SF nanofibers and 1% w/v enzymatically crosslinked...
Growth of Perovskite Film based on Lead Iodide by Controlling Deposition Parameters for Solar Cells Application
, M.Sc. Thesis Sharif University of Technology ; Mohammadi, Mohammad Reza (Supervisor) ; Seyed Reihani, Morteza (Supervisor) ; Riahi, Nastaran (Co-Advisor)
Abstract
Perovskite solar cells, with high efficiency operation, have been candidated as a cost-effective and environmentally friendly technology. Despite the great progress, there are some primarily issues remained regarding to the perovskite film and its fabrication methods. A very common perovskite cell structure is FTO/TiO2/CH3NH3PbI3/Spiro-OMeTAD/Au. Although, this structure has some advantages, lack of full surface coverage of perovskite film leads researchers to put much effort on finding other constructions. This surface inhomogeneity reduces the amount of light absorption and therefore efficiency. One way to produce a complete and uniform film is applying mixed-halide composition; such as...
Solvent Engineering for Preparation of Perovskite Film based on Lead Iodide for Solar Cells Applications
, M.Sc. Thesis Sharif University of Technology ; Seyed Reyhani, Morteza (Supervisor) ; Mohammadi, Mohammad Reza (Supervisor) ; Riahi Noori, Nastaran (Co-Advisor)
Abstract
The microstructure, morphology and quality of the perovskite organic-inorganic layer as an absorber layer in perovskite solar cells has a significant role on the efficiency and energy conversion of the device. Different solvent engineering methods have been employed to prepare the perovskite layer with the desired properties and thier reproducibility have been studied. Herein, we applied a two-step solution approach by solvent engineering method, using solvents such as isopropyl alcohol, acetone and thier mixture, for preparation of lead iodide films. Moreover, their metallurgical and photovoltaic properties were investigated. The impact of solvent engineering, using solvents such as...