Sharif Digital Repository

In this study, aqueous two-phase systems (ATPS) containing Tween 20 as a biocompatible nonionic surfactant and three different salts (NH4HPO4, NH4CH3COO and Mg(CH3COO)2 ) were prepared and their extractive potential for Lysozyme enzyme was evaluated. These systems have surfactant-rich top phase and salt-rich bottom phase. Phase equilibrium diagrams at 23 ° C were obtained by using the cloud point method and the results were successfully fitted to the Merchuk correlation and their trends were correlated with the effective excluded volume (EEV) parameter. Afterward, the partitioning behavior of the lysozyme and its extraction efficiency in the systems of Tween 20/diammonium hydrogen phosphate,... 

Oil refineries, petrochemical factories and oil platforms produce a large amount of oily wastewater every day. If these wastewaters are released in environment, it can damage soil and water seriously. Although, Biological treatment of oily wastewaters is a well-established method for remediation of these wastes, efficiency of conventional systems such as Activated Sludge, aren’t very high. Also these systems have many problems such as instability during hydraulics shocks and bulking phenomena. the hybrid bioreactor system are designed to increase the efficiency of treatment by allowing greater organic loads, increasing microbial concentration by using attached and suspended bacteria, and... 

Mechanosensitive (MS) channels are ubiquitous molecular force sensors that respond to a number of different mechanical stimuli including tensile, compressive and shear stress. One of the main mechanisms to functionally study these channels is the patch clamp technique. Here we use continuum mechanics to probe the question of how curvature, in a standard patch clamp experiment, at different length scales (global and local) affects a model MS channel. Firstly, to increase the accuracy of the Laplace’s equation in tension estimation in a patch membrane and to be able to more precisely describe the transient phenomena happening during patch clamping, we propose a modified Laplace’s equation. In... 

Mobile and wireless services industry has been among the most attractive businesses recently and is progressing at a fast pace. In this huge industry various organizations and entities cooperate to deliver value to the end user. The mobile operator plays the pivotal role in this chain. Hence mobile operator’s market was chosen in this study as the representative of the industry. Market segmentation and customer satisfaction are the main topics of this study.
Market segmentation for MCI was done using data mining with two-step algorithm. Input data included the consumer behavior extracted from mobile post-paid bills. The results indicated five distinctive clusters. The next part included... 

Titanium dioxide, due to its specific semiconductive properties, has been a highly investigated material for a variety of applications including gas sensors, hydrogen generation by water photoelectrolysis, photocatalysis, dye-sensitized solar cells and purification of water and air. Several recent studies have indicated that titania nanotubes have improved properties compared to any other form of titania for mentioned application. Titania nanotubes have been produced by a variety of methods including deposition into a template and hydrothermal processes. Anodic oxidation of titanium foil in a fluoride-based solution is one of the best methods to produce of titania nanotube arrays. Highly... 

The present M.Sc. thesis consists of two sections including the static calculation and neutron noise calculation in rectangular and hexagonal geometries. The multi-group, two dimensional neutron diffusion equations and corresponding adjoint equations are solved in the static calculation. The spatial discretization of equations is based on Average Current Nodal Expansion Method (ACNEM). Size of nodes is the same size of the fuel assemblies in modeling both of rectangular and hexagonal geometries. The results are benchmarked against the valid results for BIBLIS-2D and IAEA-2D benchmark problems. In the second section, neutron noise calculations are performed for two types of noise sources,... 

Dietary CLA production for medicinal purposes needs a safe and selective process. Biological production methods meet this goal. In this study, the microbial species that was suitable for CLA production was selected; then the CLA produced by bioconversion methods was utilized to produce CLA-enriched triglycerides by trans-esterification. Also the biochemical kinetics of CLA production and esterification reactions to produce CLA-enriched triglycerides was studied. In the presence of two substrates, the kinetics of enzymatic reaction was studied. Then the factors influencing on the microbial yield and CLA production including reaction conditions (reaction time, cell concentration and substrate... 

Cancer has been known as one of the main reasons for disease-related deaths in the last decades. Early diagnosis could significantly reduce the level of fatality chances. Among the known cancer types, lung cancer is one of the most malignant ones. The common diagnosticmethods are expensive and using high-technology methods; therefore, the introduction of simple and cheap methods is very urgent to detect it. In this project, surface and interfacial tension measurement of cancerous and normal lung cells have been investigated as an easy detection technique. Among the common measurement methods, Pendant Drop and Capillary height techniques have been utilized in this research work. The obtained... 

In this work, partitioning of amino acids such as glutamic acid, phenyl anine and tryptophan in aqueous and ionic liquid phases at 298.15 K and atmospheric pressure was measured. [C4mim][Tf2N] is used due can produce two phase with water rapidly. Studying the effect of liquid solution pH on amino acids partitioning shows that increasing of pH results in decreasing of amino acid partitioning coefficient. This phenomenon pertains to electrostatic interactions between cation of amino acid and anion of ionic liquid which reduces when pH increases. Considering the effect of pH, liquid-liquid equilibrium data of amino acids was obtained in a pH that owning maximum partioning coefficient. Chemical... 

Magnetic resonance imaging (MRI) is a highly efficient method that can provide acceptable contrast between soft tissues. But the big disadvantage of this method is that its acquisition is slow. To find the reason of being time-consuming should the procedure be surveyed. In the magnetic resonance imaging, location information obtained using phase and frequency encoding gradients. So the output is matrix of image data in the frequency domain, which is called k space. For the formation of the k space phase, need to apply gradients several times and this is the main reason of dullness of the system. Therefore, in this project using software methods try to reduce the scan time as possible. Among... 

According to human needs and in line with the development of advanced technologies, different biomedical Engineering fields like hard tissue implants are growing rapidly. Despite significant biotechnology Developments in recent years, some problems to the recognition of implants related osseointegration phenomena persist. The deficient osseointegration and implant-associated infections are key issues for the long-term clinical success of titanium and titanium alloy implants, while development of multifunctional surfaces that can simultaneously overcome these problems remains highly challenging. Therefore, the ultimate goal of this paper was to improve bone cell attachment and simultaneously... 

In this thesis, localization of a postulated noise from limited neutron detectors sparsely distributed throughout the core of a typical VVER-1000 reactor is investigated. For this purpose, developing a 2-D neutron noise simulator for hexagonal geometries based on the 2-group diffusion approximation, the reactor dynamic transfer function is calculated. The box-scheme finite difference method is first developed for hexagonal geometries, to be used for spatial discretisation of both 2-D 2-group static and noise diffusion equations. Using the discretised static equations, a 2-D 2-group static simulator (HEXDIF-2) is developed which its results are benchmarked against the well-known CITATION... 

Microrobots design and manufacturing has been one of interesting fields in robotics in recent decades. They have been designed in various types so far. In this paper a two-leg microrobot is simulated and controlled by using LuGre friction model.
The proposed microrobot is driven by a piezoelectric actuator mounted between centers of two legs. The piezoelectric is actuated by a frequency near the natural frequency of the robot. The nonlinear dynamical equations of the system are obtained considering LuGre friction model. To control the system, the equations of motion are linearized using feedback linearization method. Then a stabilizing control law is designed and the robot model is... 

The analysis of gamma-ray spectra of low resolution detectors is difficult and sometimes impossible, as a result of photo peak’s overlapping. The usual methods of radiation spectra analysis based on fitting of peaks to mathematical curves or detecting of peaks with numerical calculation, are valid for high resolution detectors. However these methods are less successful for lower resolution detectors such as the common scintillators. The wide peaks in the spectrum maybe overlap and make it difficult to analysis. To solve this problem, we test here a method, based on the use of the artificial neural network. At first spectra of elements are converted to the patterns which are suitable for the... 

The present ph.D. thesis consists of three sections including the static calculation, neutron noise calculation and neutron noise source unfolding in VVER-1000 reactor core. The multi-group, two dimensional neutron diffusion equations and corresponding adjoint equations are solved in the static calculation. The spatial discretization of equations is based on Galerkin Finite Element Method (GFEM) using unstructured triangle elements generated by Gambit software. The static calculation is performed for both linear and quadratic approximations of shape function; baesd on which results are compared. Using power iteration method for the static calculation, the neutron and adjoint fluxes with the... 

Radiation detection techniques have important applications including prompt gamma neutron activation analysis (PGNAA), radiotherapy dose measurement, medical imaging and homeland security. Pulse height distribution is also a useful parameter in Radionuclide identification. Gamma ray spectroscopy analysis is a common technique in measuring of radiation field to identify the radioactive source.
Probabilistic methods are commonly used for numerical simulation of Pulse height distribution. In Monte Carlo methods, each history is individually tracked and details of interactions are available. Using the Monte Carlo methods for calculation of pulse height distribution leads to more real... 

Neutron fluctuations in both low and high power reactors provide important information about the system. The origins of these fluctuations are different in both regimes. In low power the branching process is the reason of these fluctuations. But the random nature of technological processes such as boiling in the reactors cooling and mechanical structure vibrating such as control rod and fuel rod created the neutron noise. Mathematical descriptions and applications of neutron noise for each mode are different. In common mode, fluctuations in the neutron detection system, determine some parameters and determin the start abnormality in system. In this study the spatial dependence of the cross... 

High purity Germanium (HPGe) detector is a sub branch of semiconductor detectors which has very good resolution, very little dead time, able tobuild in large dimensions and suitable for any condition that it is using in vast fields from space investigation to radiation therapy. this detector is usually used to detecting gamma radiations furthermore the best resolution can be attained with decreasing leakage current. for analyzing about operation of the HPGe detector, it needs to initiate a model of this detector. in this studing has been used modelGEM-15190,POP-TOP which is built by ortec company. for initiating, it was used liquid nitrogen and accessory equipments like high voltage supply,... 

In operating nuclear reactor core, fluctuations (deviations from normal operating conditions) are usually produced and propagated. These fluctuations can be due to control rod vibrations, inlet coolant temperature fluctuations, inlet coolant velocity fluctuations and so on. The induced neutron noise can be detected by in-core neutron detectors. Noise source identifications (such as the type, location and propagating velocity) as well as the calculation of the dynamical parameters (such as moderator temperature coefficient in PWRs and Decay Ratio in BWRs) are of the main applications of the neutron noise analysis in power reactors.
Investigating the propagation noise in PWRs (specifically... 

Localization of a neutron point source using a designed computer program namely “MCMC-MATURE” is performed. The computer program analyses several detector responses in some certain media by Markov Chain Monte Carlo (MCMC) method and a new iteration algorithm. Identification of the possible regions of source position would be found by analyzing the initial fluxes generated by mesh tally of MCNPX computer code. The designed computer program is capable to generate the flux between detectors. “Regular-Sequential”, “Irregular-Sequential” and “Non-Sequential” are three methods used for sampling the generated random number in two dimensions. Each sample multiplied by a sampling function and lead to...