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    Poly(glycidyl methacrylate)-coated magnetic graphene oxide as a highly efficient nanocarrier: Preparation, characterization, and targeted DOX delivery

    , Article New Journal of Chemistry ; Volume 43, Issue 47 , 2019 , Pages 18647-18656 ; 11440546 (ISSN) Pourjavadi, A ; Kohestanian, M ; Yaghoubi, M ; Sharif University of Technology
    Royal Society of Chemistry  2019
    Abstract
    Herein, we report the preparation of novel magnetic graphene oxide (GO) grafted with brush polymer via surface-initiated reversible addition-fragmentation chain transfer (SI-RAFT) polymerization and its application as a nanocarrier for magnetic- and pH-triggered delivery of doxorubicin anticancer drug. The RAFT agent, DDMAT, was firstly attached to the surface of magnetic GO nanosheets. The DDMAT-functionalized magnetic GO nanosheets were then used to polymerize glycidyl methacrylate (GMA) using an SI-RAFT method. Afterwards, the epoxy rings of the PGMA chains were opened with hydrazine (N2H4) moieties. The resulting nanocomposite was used as a drug carrier for doxorubicin (DOX) as an... 

    Poly(glycidyl methacrylate)-coated magnetic graphene oxide as a highly efficient nanocarrier: Preparation, characterization, and targeted DOX delivery

    , Article New Journal of Chemistry ; Volume 43, Issue 47 , 2019 , Pages 18647-18656 ; 11440546 (ISSN) Pourjavadi, A ; Kohestanian, M ; Yaghoubi, M ; Sharif University of Technology
    Royal Society of Chemistry  2019
    Abstract
    Herein, we report the preparation of novel magnetic graphene oxide (GO) grafted with brush polymer via surface-initiated reversible addition-fragmentation chain transfer (SI-RAFT) polymerization and its application as a nanocarrier for magnetic- and pH-triggered delivery of doxorubicin anticancer drug. The RAFT agent, DDMAT, was firstly attached to the surface of magnetic GO nanosheets. The DDMAT-functionalized magnetic GO nanosheets were then used to polymerize glycidyl methacrylate (GMA) using an SI-RAFT method. Afterwards, the epoxy rings of the PGMA chains were opened with hydrazine (N2H4) moieties. The resulting nanocomposite was used as a drug carrier for doxorubicin (DOX) as an... 

    Comparison of common-mode voltage in three-phase quasi-Z-source inverters using different shoot-through implementation methods

    , Article Proceedings - 2018 IEEE 12th International Conference on Compatibility, Power Electronics and Power Engineering, CPE-POWERENG 2018 ; 4 June , 2018 , Pages 1-6 ; 9781538625088 (ISBN) Noroozi, N ; Zolghadri, M. R ; Yaghoubi, M ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2018
    Abstract
    In Z-source family inverters, shoot-through (ST) states are applied as a part of passive state in each switching cycle. The distribution of ST intervals along a switching period affects the system parameters as total harmonic distortion (THD), switching loss and common-mode voltage (CMV). In this paper, ST methods in a three-phase quasi-Z-source inverter (q-ZSI) are compared due to the CMV level. High-frequency harmonics of CMV cause leakage current flow in a transformerless grid-connected photovoltaic (PV) system. Through the comparison of the ST methods, the method with minimum CMV is identified. The experimental results are Prasented for a low voltage q-ZSI prototype. © 2018 IEEE  

    Reduced common-mode voltage in Z-source inverters

    , Article 8th Power Electronics, Drive Systems and Technologies Conference, PEDSTC 2017, 14 February 2017 through 16 February 2017 ; 2017 , Pages 413-418 ; 9781509057665 (ISBN) Noroozi, N ; Zolghadri, M. R ; Yaghoubi, M ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2017
    Abstract
    Z-source family has been widespread in photovoltaic (PV) applications. In trasformerless grid-connected PV systems, the common mode voltage (CMV) time variations, cause the leakage current flow. This current flows through the stray capacitance of the PV panels. For a Z-Source Inverter (ZSI), the CMV would have higher high-frequency harmonics, due to the shoot through states within the switching cycles. In this paper, the CMV of a ZSI is analyzed and a simple method is proposed for the harmonic reduction of the CMV in the ZSI. The CMV reduction method is based on changing the switching states. The CMV in reduced method is compared to the CMV in the traditional ZSI in frequency domain by using... 

    A novel modulation method for reducing common mode voltage in three-phase inverters

    , Article Conference Proceedings - 2017 17th IEEE International Conference on Environment and Electrical Engineering and 2017 1st IEEE Industrial and Commercial Power Systems Europe, EEEIC / I and CPS Europe 2017, 6 June 2017 through 9 June 2017 ; 2017 ; 9781538639160 (ISBN) Noroozi, N ; Zolghadri, M. R ; Yaghoubi, M ; Sharif University of Technology
    2017
    Abstract
    Leakage current is originated from common-mode voltage (CMV) time variations in a grid-connected photovoltaic (PV) system and results in several deficiencies. In this paper, a new method is proposed for CMV reduction in a three-phase voltage source inverter (VSI) system. The proposed method is based on space vector modulation and it utilizes only odd and zero vectors. By using the proposed method, the number of fluctuations of the CMV waveform per switching cycle is reduced; therefore, the amount of high-frequency harmonics of CMV is decreased. In addition, because of applying both active and zero vectors by the proposed method, the total harmonic distortion becomes less than most of other... 

    A distributed task migration scheme for mesh-based chip-multiprocessors

    , Article Parallel and Distributed Computing, Applications and Technologies, PDCAT Proceedings, 20 October 2011 through 22 October 2011 ; Oct , 2011 , Pages 24-29 ; 9780769545646 (ISBN) Yaghoubi, H ; Modarresi, M ; Sarbazi Azad, H ; Sharif University of Technology
    2011
    Abstract
    A task migration scheme for homogeneous chip multiprocessors (CMP) is presented in this paper. The proposed migration mechanism focuses on the communication sub-system and aims to reduce the total power consumption and latency of the network-on-chip (NoC). In this work, starting from an initial mapping, the tasks migrate to new cores in such a way that the distance between the end-point nodes of high-volume communication flows is reduced. Finding the new place for a task is done in a distributed manner by applying an iterative local search that relies on the local information of each task about its communication demand. The task migration procedure also includes a pre-migration step that... 

    Sound velocity in severely deformed aluminum alloys: AA1100 and AA2024

    , Article Applied Physics A: Materials Science and Processing ; Volume 126, Issue 4 , 2020 Yaghoubi, F ; Khani Moghanaki, S ; Kazeminezhad, M ; Sharif University of Technology
    Springer  2020
    Abstract
    The effects of severe plastic deformation on properties of AA1100 and AA2024 including the ultrasound velocity and the shear strength during multi-axial compression (MAC) are studied. Additionally, optical microscopy, scanning electron microscopy, and X-ray energy-dispersive spectroscopy are utilized. For both AA1100 and AA2024, an opposite trend is reported in the shear strength and the sound velocity versus deformation strain of MAC. At high strain range, AA1100 and AA2024 samples reach a plateau in the strength due to the occurrence of dynamic recovery. On the other hand, the sound velocity is shown to decrease 11% and 15% for AA1100 and AA2024, respectively. Furthermore, the... 

    A fast and cost-effective control of a three-phase stand-alone inverter

    , Article 8th Power Electronics, Drive Systems and Technologies Conference, PEDSTC 2017, 14 February 2017 through 16 February 2017 ; 2017 , Pages 67-72 ; 9781509057665 (ISBN) Mazloum, N ; Keikha, O ; Yaghoubi, M ; Tahami, F ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2017
    Abstract
    This paper proposes a straightforward control method for voltage control of a three-phase transformer-based inverter in uninterruptible power supplies or distributed generation systems. The approach offers a dual-loop design consisting inner current control loop and outer voltage loop. Sliding mode current controller provides desired bandwidth for voltage controller which consists of a state feedback term for stabilization and resonant term for harmonic damping. The proposed scheme provides fast dynamic response and low total harmonic distortion even for high power inverters with the limitations of switching frequency and LC filter components. Experimental studies for 2KVA linear and... 

    Direct Torque Control of Permanent Magnet Synchronous Machine Using Nonlinear Flux Observer

    , M.Sc. Thesis Sharif University of Technology Yaghoubi, Mokhtar (Author) ; Tahami, Farzad (Supervisor)
    Abstract
    Direct Torque Control (DTC) is one of the vector methods to control Permanent Magnet Synchronous Machines (PMSM). In order to achieve an appropriate control in vector control methods, an accurate estimation of flux is indispensable. Flux estimation should be fulfilled in a wide speed range without considerable dependence on motor parameters. Prevalent flux estimation methods are based on integration of stator voltage which is not feasible in low speed, or performed based on assumption of decoupled equations on d and q axis which is not precise for applications with fast dynamic. Different flux estimation methods are investigated in this thesis with the aim of improving the flux estimation in... 

    Design and Manufacturing Electromagnetic Actuator for Removal Brain Shunt Ventricular Catheter Obstruction

    , M.Sc. Thesis Sharif University of Technology Yaghoubi, Amin (Author) ; Akbari, Javad (Supervisor)
    Abstract
    Hydrocephalus is a desease which causes by unnatural accumulation of cerebrospinal fluid in the brain ventricles. One of the most convenient ways to treat hydrocephalus disease is to use a brain shunt which consists of ventricular catheter, valve and distal catheter. Ventricular catheter obstruction is the main reason for shunt replacement in the human brain. This project attempts to remove obstruction of the ventricular catheter by mechanical forces. For this purpose, a magnet and a variable magnetic field suggested to apply mechanical force on a brush sliding on the shunt. On the inner surface of the ring-shaped magnet, brushes have been embedded and the magnet is placed on the outer... 

    Kinematics and Dynamic Analysis of a Compliant Parallel Mechanism with Flexible Links for Micro Applications

    , M.Sc. Thesis Sharif University of Technology Yaghoubi, Reza (Author) ; Sayyadi, Hassan (Supervisor)
    Abstract
    In this research dynamic modeling of a 3-DOF (degree of freedom) compliant parallel mechanism with flexible intermediate links has been investigated. Unlike conventional rigid mechanisms that gain their mobility from movable joints, the compliant mechanisms transmit or transform through elastic deformation of flexible members (flexible connector and joint), displacement, force, or energy from input into output. Eliminating clearance, friction, wear and demand of lubrication in compliant mechanisms, and having monolithic structure provides high-precision motion with micro/nanometer level resolution for them. Therefore compliant mechanisms play a significant role in modern technologies such as... 

    Surface chemistry of atmospheric plasma modified polycarbonate substrates

    , Article Applied Surface Science ; Volume 257, Issue 23 , September , 2011 , Pages 9836-9839 ; 01694332 (ISSN) Yaghoubi, H ; Taghavinia, N ; Sharif University of Technology
    2011
    Abstract
    Surface of polycarbonate substrates were activated by atmospheric plasma torch using different gas pressure, distance from the substrates, velocity of the torch and number of treatments. The modifications were analyzed by contact angle measurements, X-ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM) and UV-vis spectrophotometry. Plasma treatment caused the surface characteristics to become more hydrophilic as measured by the water contact angle, which decreased from 88° to 18°. The decrease in contact angle was mainly due to oxidation of the surface groups, leading to formation of polar groups with hydrophilic property. XPS results showed an increase in the intensity of... 

    Loading of Doxorubicin on Stimuli-Responsive Nanocarriers and Investigation of its Release

    , M.Sc. Thesis Sharif University of Technology Yaghoubi, Mahshid (Author) ; Pourjavadi, Ali (Supervisor)
    Abstract
    Drug targeting to specific organs and tissues has become one of the critical endeavors of the new century. Magnetic nanoparticles have gained a lot of attention in biomedical and industrial application. Doxorubicin is an effective anti-cancer drug in the treatment of many types of cancers. The aim of this study is to load doxorubicin on stimuli-responsive nanocarriers. These nanocarriers are prepared from magnetic nanoparticles. Then these magnetic nanparticles are coated by copolymer of poly(glycidyl methacrylate) then reacted with hydrazine and hydrazide functional group is formed that can chemically be bonded with the anticancer drug doxorubicin via a hydrazone bond formation. This... 

    A new method for computation the success probability of coverage for switch unit in the switching systems

    , Article International Journal of Engineering Transactions C: Aspects ; Volume 33, Issue 12 , 2020 , Pages 2509-2513 Yaghoubi, A ; Gholami, P ; Sharif University of Technology
    Materials and Energy Research Center  2020
    Abstract
    Redundancy technique is used to improve performance and achieving to increase the lifetime of a system. Nowadays, the redundancy method is applied in many industries. One of the common methods of redundancy is its utilization in the switching systems. In switching systems, one or more components are considered active mode and the others in the standby state to be used by switch if necessary. In order to be fully utilized all the components in the redundant device, the switch unit must perform its function, such as switching, perfectly. Successful coverage by switch unit is expressed with a probability. In this paper, a new approach to the likelihood of switch success is proposed, and showing... 

    Design and Fabrication of Self-biased High-Tc Superconducting Radiation Detector

    , M.Sc. Thesis Sharif University of Technology Yaghoubi, Mehdi (Author) ; Fardmanesh, Mehdi (Supervisor)
    Abstract
    A bolometer is a device for measuring electromagnetic waves, which uses the heating of a material with variable resistance to temperature. Due to the existing limitations and quality improvement, superconducting materials are used in the manufacture of these devices. In this dissertation, the construction and improvement of the components of a high temperature transient edge superconducting radiometer with terahertz detection capability is discussed. In the construction of these detectors, the superconducting material YBa2Cu3O7-x is used as a thermal sensor with a transition temperature of 93.5K. In order to characterize these detectors, an automatic system for measuring the voltage response... 

    Reliability assessment of the standby system with dependent components by bivariate exponential distributions

    , Article Proceedings of the Institution of Mechanical Engineers, Part O: Journal of Risk and Reliability ; Volume 236, Issue 5 , 2022 , Pages 761-769 ; 1748006X (ISSN) Yaghoubi, A ; Gholami, P ; Sharif University of Technology
    SAGE Publications Ltd  2022
    Abstract
    In the reliability analysis of systems, all system components are often assumed independent and failure of any component does not depend on any other component. One of the reasons for doing so is that considerations of calculation and elegance typically pull in simplicity. But in real-world applications, there are very complex systems with lots of subsystems and a choice of multiple components that may interact with each other. Therefore, components of the system can be affected by the occurrence of a failure in any of the components. The purpose of this paper is to give an explicit formula for the computation of the reliability of a system with two parallel active components and one spare... 

    Modeling self-assembly of the surfactants into biological bilayer membranes with special chemical structures using dissipative particle dynamics method

    , Article Scientia Iranica ; Volume 23, Issue 3 , 2016 , Pages 942-950 ; 10263098 (ISSN) Yaghoubi, S ; Pishevar, A. R ; Saidi, M. S ; Shirani, E ; Sharif University of Technology
    Sharif University of Technology  2016
    Abstract
    The aim of this study is to simulate the self-assembly of the surfactant molecules with special chemical structure and bending stiffiness into bilayer membranes using a mesoscopic Dissipative Particle Dynamics (DPD) method. The surfactants are modeled with special chemical structure and bending stiffiness. To confirm that the novel model is physical, we determine the interaction parameters based on matching the compressibility and solubility of the DPD system with real physics of the uid. To match the mutual solubility for binary uids, we use the relation between DPD parameters and x-parameters in Flory-Huggins-type models. Unsaturated bonds can change the stiffiness of a lipid membrane,... 

    IGBT open-circuit fault diagnosis in a Quasi-Z-source inverter

    , Article IEEE Transactions on Industrial Electronics ; Volume 66, Issue 4 , 2019 , Pages 2847-2856 ; 02780046 (ISSN) Yaghoubi, M ; Shokrollahi Moghani, J ; Noroozi, N ; Zolghadri, M. R ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2018
    Abstract
    In this paper, a fast and practical method is proposed for open-circuit (OC) fault diagnosis (FD) in a three-phase quasi-Z-source inverter (q-ZSI). Compared to the existing fast OC FD techniques in three-phase voltage-source inverters (VSIs), this method is more cost-effective since no ultra-fast processor or high-speed measurement is required. Additionally, the method is independent of the load condition. The proposed method is only applicable to Z-source family inverters and is based on observing the effect of shoot-through (SH) intervals on the system variables during switching periods. The proposed algorithm includes two consecutive stages: OC detection and fault location identification.... 

    IGBT Open-circuit fault diagnosis in a quasi-z-source inverter

    , Article IEEE Transactions on Industrial Electronics ; Volume 66, Issue 4 , 2019 , Pages 2847-2856 ; 02780046 (ISSN) Yaghoubi, M ; Moghani, J. S ; Noroozi, N ; Zolghadri, M. R ; Sharif University of Technology
    Institute of Electrical and Electronics Engineers Inc  2019
    Abstract
    In this paper, a fast and practical method is proposed for open-circuit (OC) fault diagnosis (FD) in a three-phase quasi-Z-source inverter (q-ZSI). Compared with the existing fast OC FD techniques in three-phase voltage source inverters, this method is more cost-effective since no ultrafast processor or high-speed measurement is required. Additionally, the method is independent of the load condition. The proposed method is only applicable to Z-source family inverters and is based on observing the effect of shoot-through intervals on the system variables during switching periods. The proposed algorithm includes two consecutive stages: OC detection and fault location identification. When both... 

    Covalent immobilization of cellulase using magnetic poly(ionic liquid) support: improvement of the enzyme activity and stability

    , Article Journal of Agricultural and Food Chemistry ; Volume 66, Issue 4 , 2018 , Pages 789-798 ; 00218561 (ISSN) Hosseini, H ; Hosseini, A ; Zohreh, N ; Yaghoubi, M ; Pourjavadi, A ; Sharif University of Technology
    American Chemical Society  2018
    Abstract
    A magnetic nanocomposite was prepared by entrapment of Fe3O4 nanoparticles into the cross-linked ionic liquid/epoxy type polymer. The resulting support was used for covalent immobilization of cellulase through the reaction with epoxy groups. The ionic surface of the support improved the adsorption of enzyme, and a large amount of enzyme (106.1 mg/g) was loaded onto the support surface. The effect of the presence of ionic monomer and covalent binding of enzyme was also investigated. The structure of support was characterized by various instruments such as FT-IR, TGA, VSM, XRD, TEM, SEM, and DLS. The activity and stability of immobilized cellulase were investigated in the prepared support. The...