Sharif Digital Repository

Lipases (triacylglycerol acylhydrolases) are industrial enzymes that have wide applications in the detergent, pharmaceutical and food industries. Pseudomonas aeruginosa strain is known to be suitable for lipase production due to its stability in organic solvents, resistance to temperature and pH. Lipases are usually secreted extracellularly, and its isolation from the culture medium is very important. The most cost-effective separation method is filtration which is more economical than centrifuge. Here, the use of filtration method is important from two aspects of creating clearance and maintaining enzyme activity. The equipment in this research is the filter press, whose initial tests are... 

In all types of chromatography for the extraction and purification of proteins, a fixed substrate is needed with which the mobile phase containing the proteins interact with them. This fixed bed should contain grains that have characteristics such as sphericity, high surface area, hydrophilicity, binding power to functional groups, chemical stability, low specific absorption, reusability and low cost. Commercially, the most commonly substrates in the ranges of the molecular weight of proteins are agarose and dextran. Agar was extracted from Gracilaria salicornia seaweed and removal of ionic groups was investigated by three methods. In washing with isopropanol, the ionic groups were reduced... 

Enzymes are biological catalysts that reduce the activation energy of a reaction in a short time and thus increase the speed of the reaction. The most common enzymes used in various industries, including the detergent industry, are lipases, amylases, celluloses, and proteases. Proteases are one of the most important industrial enzymes. The performance of enzymes is affected by the durability of their activity in long-term storage. Therefore, using a technique that can maintain the activity of enzymes, under storage and usage conditions, is an essential step in making a product containing enzymes. Stabilization-immobilization operation is one of the important downstream processes in... 

In this research, after examining the different strains available in the enzyme center's cell bank, the bacterial strain Pseudomonas aeruginosa (RPMC-B-3556) obtained from the Russian microbial collection was used for lipase production. This microbial strain has the ability to produce extracellular lipase enzyme and for this reason it has been selected as the target strain. The purpose of this research was to optimize the lipase production process in the culture of the appropriate strain. For this purpose, the compounds used in the culture medium are changed to investigate their effect on lipase enzyme activity. Considering that the studied strain has the ability to produce protease enzyme... 

Storage tanks are always under different hazards such as corrosion and leaking. In this thesis after studding current damaged detection methods, a new method of corrosion monitoring on storage tanks was performed. Fiber optic technology was explained and Fiber Bragg grating (FBG) was chosen as a sensor. Modeling of optical fiber and storage tank was performed in ANSYS and corrosion damage, in the form of pitting, in two possible states of occurrence was presented. The effect of change of strain, thickness, loading, length, and wavelength on each other was presented in different graphs. The results showed that by decreasing thickness of elements, strain in the damaged area increased and by... 

Studies show that Pedestrians are at fault in 59% of the vehicle-pedestrian accidents. The traffic crash statistics show the importance of understanding factors of pedestrian errors. If pedestrians terminate their waiting behavior during the red light period and cross the street, they would put themselves in danger. Pedestrians’ red-light violation is a type of highly dangerous behavior occurring at intersections. A total of 1130 pedestrians approaching the intersections during red light periods were observed from the videotapes data collected at 6 intersections in Tehran, Iran. Pedestrian crossing behaviors are classified into immediate crossing behavior and waiting behavior. A logit model... 

According to prediction of ITRS, power consumption and bandwidth of processors' interconnection, will be the most major bottleneck of the System-on- Chips (SoCs) in the future. Therefore, in MultiProcessor System-on-Chip (MPSoC) architectures, the design constraints will be altered from "Computational Constraints" to "Communicational Constraints". There are three kinds of communications in the surface of the chip: Global, median and local. The main difference between global and local connections is that the length of latter one will be changed with technology. In other words, it is scalable like processor's elements while the length of global connections is practically constant. Even though... 

According to power limitation on a chip and the need to simultaneously access high utilization and low power consumption, Multi-Processor System-on-Chip (MPSoC) architectures have been introduced. The major part of power consumption in a network on chip belongs to interconnects. One of the most important issues is to decrease power consumption while maintaining high utilization. The ability of optical interconnects in decreasing power consumption and increasing utilization has introduced a new architecture called optical network on chip. This architecture uses the benefits of optical signals and elements in order to transfer data. In this thesis, we introduce a new architecture with... 

Recently, a new tool in the study of two-dimensional continuous phase transition was provided by Schramm-Loewner evolution. The main part of SLE is a conformal map which relates growth process of a two-dimensional simple curve to one-dimensional motion on the real axis (so-called Loewner driving function). Time evolution of this map and Loewner driving function is connected via the Loewner differential equation. It turns out that for a certain class of stochastic and conformally invariant curves in two dimensions, the driving function shows Brownian motion in one dimension. Strength point of SLE comes from this fact that all the geometrical properties of such curves is described through a... 

Schramm Loewner evolution (SLE) is a one-parameter family of random simple curves in the complex plane introduced by Schramm in 1999 which is believed to describe the scaling limit of a variety of domain interfaces at criticality. This thesis is concerned with statistical properties of watersheds dividing drainage basins. The fractal dimension of this model is 1.22 which is consistent with the known fractal dimension for several important models such as Invasion percolation and minimum spanning trees (MST). We present numerical evidences that in the scaling limit this model are SLE curves with =1.73, being the only known physical example of an
SLE with <2. This lies outside the... 

Nowadays by increasing the number of processing cores in system-on-chip, using networks-on-chip, as an optimized interconnection foundation for transferring data between processing cores is inevitable .Based on this, the necessity of designing and implementing an optimized structure for testing network-on-chip, considering various overheads such as power consumption, latency, bandwidth and area, becomes an important issue in designing network-on-chip. The purpose of this project is to design an optimized structure for testing routers and connecting links in network, which considers power consumption overhead, latency and area overhead on one hand, and fault coverage on the other hand.... 

As the number of processing cores on a single chip continues to grow, the need for a high band width, low power communication structure, will be the most important requirements of next generation chip multiprocessors. Today, a major part of power consumption in multi core architectures belongs to interconnects. Due to these facts, reducing consuming power, as well as supporting high performance, is concerned in these architectures. The concept of “network-on-chip” emerged to improve the performance of CMPs. But now a day, considering the circumstances of power budges, it’s incapable of presenting new strategies to decrease consuming power and delay. However, optical interconnects have the... 

Nowadays, a large proportion of the power consumption in high-performance multi-processor architectures on chip belongs to connections. Reducing power consumption while maintaining high efficiency in these architectures is one of the main concerns. Networks on Chip (NoC) originally were introduced to improve efficiency, but now, given the importance of power, we must provide some solutions to reduce power consumption, and delay in NOCs. Connections in chip can be divided into three categories: global, intermediate and local, while the length of global connections is almost constant in different scales, local connections are scalable. As a result improving efficiency of a small number of... 

Brown and Henneaux showed that asymptotic symmetries of asymptotically form a conformal group in two dimensions [1]. Also they could derive classical central charge of theory. Fourteen years later, Maldacena, conjectured that this Holographic correspondence could be true for a specific theory a simplified chromodynamics in the boundary of ), this holographic theory attracted physicist communitee's attention. Many physicists tried to make this conjecture more precise. It is worth to say that, no example of holographic correspondence has been completely proven, till now, Because of the difficulty of the calculation. However these days we consider Madacena conjectrure in any arbitrary... 

In this thesis, a hardware is designed and implemented for testing the perfoemance of MIMO communication systems in LTE standard using SCM channel model. This hardware can be used for measuring the BER of 2x2 wireless systems. This hardware is the first channel emulator, with hardware implementation which is using SCM channel model and implementation of a similar one has not been reported.In addition to the implementation of the mentioned channel emulator, a new approach is used for implementing a Gaussian variate generator (GVG) which is implemented on both FPGA and ASIC and shows better characteristics in comparison with the works done in the past. ASIC implementation of this part is done... 

With constant increase in the rate of VLSI circuits manufactured in sites separate from the designers and computer architects, global concern regarding the possibility of integration of malware by the manufacturing foundries has arisen. Particularly, one main issue that affects reliability of the chips is modifications or additions with malicious intention,known as Hardware Trojans, which are easily applicable during design and manufacturing phase of chips. There has been an increasing fraud in chip-set manufacturing. Hardware Trojans may leak confidential information outside the chip, to the attacker, may alter the function of circuit, or completely fail a system. Hence search for new... 

With the widespread use of mobile applications, multimedia and telecommunications, speed of execution has become important. The computation-intensive portions of applications, i.e., loops, devote a significant percentage of their implementation time. Thus, in this thesis, a new method is introduced which greatly increases the execution speed of the loops. Loops are often implemented on coarse-grained reconfiguration architecture (CGRAs) for acceleration, which is a promising architecture with high performance and high power efficiency in comparison to FPGA. In this regard, to reduce the execution time of two-level nested loops, if there are several innermost loops, first, we fuse them, then... 

Today's latest technology integrated circuits are manufactured for a wide range of applications. With the constant increase in the usage rate of integrated circuits, designing a high reliable system is of utmost importance. The avoidance of counterfeit components is a major challenge of hardware security and trust. Counterfeit components cause lower performance and reduced life span. They are of great concern to the manufacturers and consumers of electronic systems, impacting the security and reliability of these systems. If these parts end up in critical applications like medical systems, satellites, aerospace, or power plants, the results could be catastrophic. So far, there are different...