Sharif Digital Repository

Blood transfusion services are vital components of healthcare systems all over the world. In this paper, a generalized network optimization model is developed for a complex blood supply chain in accordance with Iranian blood transfusion organization (IBTO) structure. This structure consist of four types facilities. Blood collection centers, blood collection and processing centers, mobile teams and blood transfusion center have various duties in IBTO structure. The major contribution is to develop a novel hybrid approach based on stochastic programming, ε-constraint and robust optimization (HSERO) to simultaneously model two types of uncertainties by including stochastic scenarios for total... 

Background: Once aligned, long-reads can be a useful source of information to identify the type and position of structural variations. However, due to the high sequencing error of long reads, long-read structural variation detection methods are far from precise in low-coverage cases. To be accurate, they need to use high-coverage data, which in turn, results in an extremely time-consuming pipeline, especially in the alignment phase. Therefore, it is of utmost importance to have a structural variation calling pipeline which is both fast and precise for low-coverage data. Results: In this paper, we present SVNN, a fast yet accurate, structural variation calling pipeline for PacBio long-reads... 

Background: Once aligned, long-reads can be a useful source of information to identify the type and position of structural variations. However, due to the high sequencing error of long reads, long-read structural variation detection methods are far from precise in low-coverage cases. To be accurate, they need to use high-coverage data, which in turn, results in an extremely time-consuming pipeline, especially in the alignment phase. Therefore, it is of utmost importance to have a structural variation calling pipeline which is both fast and precise for low-coverage data. Results: In this paper, we present SVNN, a fast yet accurate, structural variation calling pipeline for PacBio long-reads... 

Background: Long reads provide valuable information regarding the sequence composition of genomes. Long reads are usually very noisy which renders their alignments on the reference genome a daunting task. It may take days to process datasets enough to sequence a human genome on a single node. Hence, it is of primary importance to have an aligner which can operate on distributed clusters of computers with high performance in accuracy and speed. Results: In this paper, we presented IMOS, an aligner for mapping noisy long reads to the reference genome. It can be used on a single node as well as on distributed nodes. In its single-node mode, IMOS is an Improved version of Meta-aligner (IM)... 

Now days titanium dioxide is used in different applications because of its good electrical properties, optical stability and cost savings. According to their different nanoscale TiO2 structures, it has been determined that 1D structures such as nanorods, nanotubes and nanowires has better properties than the other structures, including enhancing electron transport and create an offered directional way of transporting of the electrons. However, the grain boundaries in polycrystalline TiO2 nanowires or nanotubes cause electron scattering or trapping, which limit their application in optoelectronics. From these TiO2 structures, TiO2 nanorods have special importance because of less defects... 

OFDM is a multicarrier modulation scheme with high bandwidth efficiency and robustness to multipath environment used in high data rate transmission. However, a drawback of this system is the large Peak-to-Average-Power Ratio (PAR) of the transmit signal which makes its straightforward implementation quite costly. PAR in an OFDM based system can be reduced significantly by PTS method for which data recovery requires side information (SI) about the phases used at transmitter. Sending SI, not only reduces the rate, but also increases BER, for any error in SI detection can damage a large amount of transmitted information. By introducing a new phase set, we propose a PTS based method for MPSK... 

Simulation is the gold standard for training in aviation and trauma medicine. Now it is available for diseases diagnosis and treatment. With simulation, clinicians can practice their art in a realistic, consequence free environment, combining both theory and practice in a comprehensive program. Method and materials - In the virtual clinical environment of "VPsoft mentor" software, the practitioner reviews a patient's history, orders laboratory tests and procedures, interprets findings, renders diagnoses, and prescribes medication. Every diagnostic or treatment decision the clinician makes for the patient is analyzed by E-mentor, providing instant feedback.Results - This software have been... 

In this paper, the behavior of a fractional order Van der Pol-like oscillator is investigated using a describing function method. A parametric function for the boundary between oscillatory and nonoscillatory regions of this system is extracted. The analytical results are evaluated by numerical simulations which demonstrate sufficient reliability of the proposed analyzing method  

The use of Computer Science in order to categorize and store information, improve diagnostic and therapeutic procedures, patient education and the training of a skilled labor force, has taken important steps and there are constantly new developments in this area  

The cooperative relay cognitive interference channel (RCIC) is a four-node network with two source nodes (primary source and cognitive source) and two destination nodes, in which sources try to communicate at certain rates with their corresponding destinations simultaneously through a common medium and each destination can act as a relay to assist the other one. For the partially cooperative RCIC (PC-RCIC), in which only one of the destinations (corresponding to the cognitive source) acts as a relay, we derive an achievable rate region based on using rate splitting and superposition coding at the cognitive source, and using decode-and-forward scheme at the relay. For the degraded PC-RCIC, we... 

MapReduce and its open source implementation, Hadoop, have gained widespread adoption for parallel processing of big data jobs. Since the number of such big data jobs is also rapidly rising, reducing their energy consumption is increasingly more important to reduce environmental impact as well as operational costs. Prior work by Mashayekhy et al. (IEEE Trans. Parallel Distributed Syst. 26, 2720–2733, 2016), has tackled the problem of energy-aware scheduling of a single MapReduce job but we provide a far more efficient heuristic in this paper. We first model the problem as an Integer Linear Program to find the optimal solution using ILP solvers. Then we present a task-based greedy scheduling... 

This paper provides empirical evidence on a novel complementarity between VAT and trade taxes. Downstream domestic firms require VAT receipts from importers to claim VAT on purchases, increasing incentives for honest reporting of imports. Trade gap, the difference between mirror and domestic trade reports in Iran at 6-digit HS disaggregation, is used to measure this complementarity. Iran introduced VAT in 2008 and, since then, has increased its rate from 3 to 9 percent. Difference-in-differences estimates show that a 1 percentage point increase in the VAT rate reduces the trade gap by about 2 percent. Consistent with the compliance mechanisms for VAT, a smaller effect for consumer products... 

This paper is devoted to the analysis of fractional order Van der Pol system studied in the literature. Based on the existing theorems on the stability of incommensurate fractional order systems, we determine parametric range for which a fractional order Van der Pol system with a specific order can perform as an undamped oscillator. Numerical simulations are presented to support the given analytical results. These results also illuminate a main difference between oscillations in a fractional order Van der Pol oscillator and its integer order counterpart. We show that contrary to integer order case, trajectories in a fractional Van der Pol oscillator do not converge to a unique cycle. © 2009... 

In this letter, we surpass the jamming effect and also estimate the jamming channel state information by using Kalman filtering (KF) approach. Furthermore, we design a closed-form beamforming weight for maximizing the achievable rate subject to the condition that the total relays power transmission would be below a predefined threshold level, which is formulated as a Quadratically Constrained Quadratic Program (QCQP). Simulation results show efficient performance of the proposed method for different destruction powers of jammer by achieving the Cramer Rao Lower Bound (CRLB). IEEE  

Strong Designated Verifier Signature (SDVS) provides authentication for the signer and the verifier such that the signer is assured that what s/he has signed, is only verified by the designated verifier. Currently, the security of most of the SDVS schemes is based on hard problems in the number theory. As it is proved that all kinds of cryptosystems which are based on the number theory will not tolerate quantum attacks, here, an SDVS scheme based on hard problems in coding theory is presented. We have proved that the suggested scheme is unforgeable under a chosen message attack in Random Oracle Model. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd  

In this letter, we surpass the jamming effect and also estimate the jamming channel state information by using the Kalman filtering approach. Furthermore, we design a closed-form beamforming weight for maximizing the achievable rate subject to the condition that the total relays power transmission would be below a predefined threshold level, which is formulated as a quadratically constrained quadratic program. Simulation results show the efficient performance of the proposed method for different destruction powers of the jammer by achieving the Cramér-Rao lower bound. © 1997-2012 IEEE  

A very efficient and mild procedure for the trimethylsilylation of a wide variety of alcohols, including primary, allylic, benzylic, secondary, hindered secondary, tertiary, and phenols with hexamethyldisilazane on the surface of silica gel dispersed with LiClO4 in room temperature at few minutes in excellent yields under neutral conditions is reported. This procedure also allows the excellent selectivity under LP-SiO2 system for silylation of alcohols in the presence of amine and phenolic hydroxy groups  

In a cloud storage service, public auditing mechanisms allow a third party to verify integrity of the outsourced data on behalf of data users without the need to retrieve data from the cloud server. Recently, Shen et al. proposed a new lightweight and privacy preserving cloud data auditing scheme which employs a third party medium to perform time-consuming operations on behalf of users. The authors have claimed that the scheme meets the security requirements of public auditing mechanisms. In this paper, we show that Shen et al.'s scheme is insecure by proposing two attacks on the scheme. In the first attack, an outside adversary can modify some messages in transmission to the cloud server... 

Cloud storage has significantly reduced data management costs for data owners. However, loss of physical control over the data after outsourcing, triggers some security concerns such as data integrity. Provable Data Possession (PDP) protocols, enable data owners to audit the integrity of their outsourced data without the need to retrieve the file from cloud server. However, most existing PDP schemes require resource-constrained users to perform costly operations for generating metadata on file blocks. In online/offline PDP mechanisms introduced most recently, the user’s computation is divided into online/offline phases, where the costly operations are allowed to be carried out in the offline...