Sharif Digital Repository

The main aim of the present work was to collect and categorize anti-HIV molecules in order to identify general structure-activity relationships. In this respect, a total of 5580 drugs and drug-like molecules was collected from 256 different articles published between 1992 and 2010. An algorithm called genetic algorithm-pattern search counterpropagation artificial neural networks (GPS-CPANN) was proposed for the classification of compounds. In addition, the CART (classification and regression trees) method was used for construction of decision trees and finding the best molecular descriptors. The results revealed that the developed CPANN models and decision tree can correctly classify the... 

This paper proposes a methodology for generating surrogate single-degree-of-freedom (SDOF) models that can be utilized to estimate the probability distribution of the roof drift ratio of multistory buildings at various ground motion intensity measures. The use of an SDOF model as a surrogate for multistory buildings can significantly alleviate the high computational cost for probabilistic seismic demand assessment considering both model uncertainty and record-to-record variability. The surrogate SDOF model generated herein explicitly accounts for model uncertainties and can be used as an alternative to the nonlinear dynamic analysis of detailed building structures. Applications for such... 

In this paper, a special class of redundancy optimization problem with fuzzy random variables is presented. In this model, fuzzy random lifetimes are considered as basic parameters and the Er-expected of system lifetime is used as a major type of system performance. Then a redundancy optimization problem is formulated as a binary integer programming model. Furthermore, illustrative numerical examples are also given to clarify the methods discussed in this paper  

In this study, a supply chain model consisting of a single product, one supplier and one retailer is considered. Transportation times are constant and demands at the retailer are assumed to be generated by a stationary Poisson process. Demands not covered immediately from inventory are backordered. The retailer carries inventory and replenishes stock according to a (Q, R) policy. The supplier has online information about the demand at the retailer and uses this information to replenish its stock. The order size at the supplier is a multiple integer to the retailer's order size. Considering order costs for the retailer and the supplier, we derive the exact cost function for this inventory... 

In this paper, first a fuzzy random resource-constrained project scheduling problem is presented. The object of the problem is to find the optimal scheduling of project activities. In this model, duration of project activities is a fuzzy random variable. Then, the proposed model is formulated by using the expected value of fuzzy random variables as an IP model. An illustrative example is also provided to clarify the concept. © 2010 World Academic Press, UK. All rights reserved  

This paper considers flocking to the virtual leader in network of agents with double-integrator. A locally linear algorithm is employed which guarantees exponential flocking to the virtual leader. A lower bound for flocking rate is calculated which is independent of the initial conditions. Simulations are provided to validate the result and it is shown that the calculated rate is not over bound the actual convergence rate. The effect of coefficients of algorithm is investigated and it is shown that the similar results can be inferred from the calculated formula for the convergence rate. Copyright  

A novel semi-active control system for suspension systems of passenger car using Magnetorheological (MR) damper is introduced. The suspension system is considered as a mass-spring model with an eight-degrees-of-freedom, a passive damper and an active damper. The semi-active vibration control is designed to reduce the amplitude of automotive vibration caused by the alteration of road profile. The control mechanism is designed based on the optimal control algorithm, Linear Quadratic Regulator (LQR). In this system, the damping coefficient of the shock absorber changes actively trough inducing magnetic field. It is observed that utilizing the present control algorithm may significantly reduce... 

In this paper, a replacement-repair model is developed to study a warranty servicing policy for a class of multi-state deteriorating and repairable products, based on a computer simulation analysis. In each working state there is a determined probability for transition to each of the subsequent states, given that it has made a transition out of that state. There are two parameters that determine the manufacturer's decision to repair or replace a failed item, assuming that the buyer's claim is valid; the deterioration degree of the item and the length of the residual warranty period. Beside these two parameters, other inputs to the model are: the number of working and failure states, the... 

We use the topological entanglement entropy (TEE) as an efficient tool to fully characterize the Abelian phase of a Z2 ×Z2 spin liquid emerging as the ground state of topological color code (TCC), which is a class of stabilizer states on the honeycomb lattice. We provide the fusion rules of the quasiparticle (QP) excitations of the model by introducing single- or two-body operators on physical spins for each fusion process which justify the corresponding fusion outcome. Besides this, we extract the TEE from Renyi entanglement entropy (EE) of the TCC, analytically and numerically by finite size exact diagonalization on the disk shape regions with contractible boundaries. We obtain that the EE... 

In discussions related to reliability optimization using redundancy allocation, one of the structures that has attracted the attention of many researchers, is series-parallel structure. In models previously presented for reliability optimization of series-parallel systems, there is a restricting assumption based on which all components of a subsystem must be homogeneous. This constraint limits system designers in selecting components and prevents achieving higher levels of reliability. In this paper, a new model is proposed for reliability optimization of series-parallel systems, which makes possible the use of non-homogeneous components in each subsystem. As a result of this flexibility,... 

In many real world optimization problems, including Redundancy Allocation Problem (RAP), there is a need to optimize more than one objective function simultaneously. In this paper, a new multi-objective formulation is presented for the RAP by considering the reliability and cost of the system as the objective functions. The previous formulations have been proposed based on the assumption that all components of a subsystem are homogeneous. This constraint leads to an increase in the designing cost and prevents from reaching to higher quantities of the system reliability. The presented formulation in this research provides an opportunity for the subsystems components to be non-homogeneous in... 

Using the infinite projected entangled pair states algorithm, we study the ground-state properties of the spin-1/2 quantum Heisenberg antiferromagnet on the star lattice in the thermodynamic limit. By analyzing the ground-state energy of the two inequivalent bonds of the lattice in different unit-cell structures, we identify two competing valence-bond-solid (VBS) phases for different antiferromagnetic Heisenberg exchange couplings. More precisely, we observe (i) a VBS state which respects the full symmetries of the Hamiltonian, and (ii) a resonating VBS state which, in contrast to previous predictions, has a six-site unit-cell order and breaks C3 symmetry. We also studied the ground-state... 

We present a general graph-based projected entangled-pair state (gPEPS) algorithm to approximate ground states of nearest-neighbor local Hamiltonians on any lattice or graph of infinite size. By introducing the structural matrix, which codifies the details of tensor networks on any graphs in any dimension d, we are able to produce a code that can be essentially launched to simulate any lattice. We further introduce an optimized algorithm to compute simple tensor updates as well as expectation values and correlators with a mean-field-like effective environments. Though not being variational, this strategy allows to cope with PEPS of very large bond dimension (e.g., D=100) and produces... 

In this paper, we consider a dual-sourcing model with constant demand and stochastic lead times. Two suppliers may be different in terms of purchasing prices and lead-time parameters. The ordering takes place when the inventory level depletes to a reorder level, and the order is split among two suppliers. Unlike previous works in the order splitting literature, the supply lead time between vendor and buyer as well as unit purchasing prices is considered to be order quantity dependent. The proposed model finds out the optimal reorder point, order quantity and splitting proportion, using a solution procedure. Numerical results show that neglecting the relationship between ordering batch size... 

Adsorption of human serum proteins (Albumin and total protein) onto high purity synthesis nano-hydroxyapatite (HA), Ca 10(PO 4) 6(OH) 2, has been studied in a wide temperature range by UV-visible spectrophotometer. Adsorption isotherm is basically important to describe how solutes interact with adsorbent, andiscriticalinoptimizing the use of adsorbent. Inthe present study, the experimental results werefitted tothe Langmuir, Freundlich, Temkin and Dubinin-Radushkevich (DR) models to obtain the characteristic parameters of each model and square of the correlation coefficients (R 2). According to the results, the DR isotherm model had the best agreement with the experimental data. The effect of... 

An electric power supply is the backbone of development in advanced as well as in developing economies. An integral part of ensuring a secure power supply system is a power communication system. Due to the high and sustained performance requirements of power communication systems, electric companies prefer to construct their own communication networks privately rather than relying solely on a public communication system. The focus of this paper is on the optimal topological design of a power communication network. Based on advanced optimization models in public communication networks, and taking into account the specific Quality of Service, as demanded by various applications, such as...