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Cancer Simulation with Markov Decision Process
, M.Sc. Thesis Sharif University of Technology ; Habibi, Jafar (Supervisor)
Abstract
Cancer is refer to a class of diseases that create as the result of abnormal growth of cells and invasion of them to normal cells of human body, and annually cause the considerable percentage of death in the world. Because cancer can be considered as a complex system, various models presented to modeling and simulation of the behavior of it, using of different methods such as cellular automata, agent-based, game theory and other methods. Multi-agent simulation models as a special kind of agent-based models, is a method that used to simulate some real-world phenomena that usually contains many different components and interact using different and complex ways. Since the cells are located in...
Synthesis and Optimization of Endohedral Metall of Ullerene Production in Arc Reactor Applying Vertical Graphite Electrodes
, M.Sc. Thesis Sharif University of Technology ; Ghanbari, Bahram (Supervisor)
Abstract
One of the considerable issues in fullereneresearch is low yield of endohedral fullerene production.In this project, synthesis and optimization of endohedral metallofullereneproduction was undertaken byarc reactor applying vertical graphite electrodes, using vaporizing composite lanthanum-oxide-graphite-dopped rod. Increasing the efficiency of endohedral fullerrene production in sootwas followed applyingcarbide formation in electrode which was studied by X-ray diffraction(XRD), thermogravimetric analysis(TGA) and infrared (IR) spectroscopy. In addition, as a simple and fast method, the liquid column chromatography was applied in separation and purification of fullerenes as well as endohedral...
Synthesis and Study on Complexation of Naphthalene Azacrown Macrocycle Ligands with [60] Fullerene and Metal Cations Like Cu2+
, Ph.D. Dissertation Sharif University of Technology ; Ghanbari, Bahram (Supervisor)
Abstract
In the present research, two series of N2O2- and N4O2-naphthadiaza-crown macrocyclic ligands with different macroring size, 15-21 memberd (L1-L7) were synthesized using direct method. The products were characterized by applying 1H and 13C NMR, IR spectroscopy, mass spectrometry and elemental analysis and in some cases by X-ray crystallography. Firstly, to study on emission properties of naphthadiaza-crown macrocyclic ligands as a fluorophore, we employed different amines as fluorescence quencher. It was observed that the quenching effects of 3o aliphatic amines like triethylamine were more pronounce than other group of amines. Also, the quenching constants for interactions of macrocyclic...
Gold nanorods for drug and gene delivery: An overview of recent advancements
, Article Pharmaceutics ; Volume 14, Issue 3 , 2022 ; 19994923 (ISSN) ; Mousazadeh, M ; Taji, S ; Bahmani, A ; Zarepour, A ; Zarrabi, A ; Sharifi, E ; Azimzadeh, M ; Sharif University of Technology
MDPI
2022
Abstract
Over the past few decades, gold nanomaterials have shown great promise in the field of nanotechnology, especially in medical and biological applications. They have become the most used nanomaterials in those fields due to their several advantageous. However, rod-shaped gold nanoparticles, or gold nanorods (GNRs), have some more unique physical, optical, and chemical properties, making them proper candidates for biomedical applications including drug/gene delivery, photothermal/photodynamic therapy, and theranostics. Most of their therapeutic applications are based on their ability for tunable heat generation upon exposure to near-infrared (NIR) radiation, which is helpful in both...
A context-based privacy preserving framework for wearable visual lifeloggers
, Article 2016 IEEE International Conference on Pervasive Computing and Communication Workshops, PerCom Workshops 2016, 14 March 2016 through 18 March 2016 ; 2016 ; 9781509019410 (ISBN) ; Hosseini, M ; Kanhere, S. S ; Sowmya, A ; Sharif University of Technology
Institute of Electrical and Electronics Engineers Inc
2016
Abstract
The ability of wearable cameras to continuously capture the first person viewpoint with minimal user interaction, has made them very attractive in many application domains. Wearable technology today is available and useful but not widely used and accepted due to various challenges mainly privacy concerns. In this paper, we introduce a novel efficient privacy-aware framework for wearable cameras that can protect all sensitive subjects such as people, objects (e.g, display screens, license plates and credit cards) and locations (e.g, bathrooms and bedrooms). It uses the contextual information obtained from the wearable's sensors and recorded images to identify the potential sensitive subjects...
Characterizing terahertz channels for monitoring human lungs with wireless nanosensor networks
, Article Nano Communication Networks ; Volume 9 , 2016 , Pages 43-57 ; 18787789 (ISSN) ; Hassan, M ; Chou, C. T ; Ebrahimi Warkiani, M ; Sharif University of Technology
Elsevier B.V
2016
Abstract
We characterize terahertz wireless channels for extracting data from nanoscale sensors deployed within human lungs. We discover that the inhalation and exhalation of oxygen and carbon dioxide causes periodic variation of the absorption coefficient of the terahertz channel. Channel absorption drops to its minimum near the end of inhalation, providing a window of opportunity to extract data with minimum transmission power. We propose an algorithm for nanosensors to estimate the periodic channel by observing signal-to-noise ratio of the beacons transmitted from the data sink. Using real respiration data from multiple subjects, we demonstrate that the proposed algorithm can estimate the minimum...
SEMON: sensorless event monitoring in self-powered wireless nanosensor networks
, Article ACM Transactions on Sensor Networks ; Volume 13, Issue 2 , 2017 ; 15504859 (ISSN) ; Hassan, M ; Chou, C. T ; Adesina, A. A ; Sharif University of Technology
Association for Computing Machinery
2017
Abstract
A conventional wireless sensor network node consists of a number of components: microprocessor, memory, sensor, and radio. Advances in nanotechnology have enabled the miniaturization of these components, thus enabling wireless nanoscale sensor networks (WNSN). Due to their small size, WNSN nodes are expected to be powered by harvesting energy from the environment. Unfortunately, there is a mismatch in the energy that can be harvested and the energy required to power all the aforementioned components in a WNSN node. In this article, we propose a simplified sensor node architecture for event detection. We call our architecture Sensorless Event MONitoring in self-powered WNSNs (SEMON). A SEMON...
Monodentate palladium(0)-[60]fullerene complexes of diphosphine ligands as efficient and sustainable nanocatalysts for the Mizoroki-Heck coupling reaction of aryl chlorides
, Article New Journal of Chemistry ; Volume 41, Issue 18 , 2017 , Pages 9701-9709 ; 11440546 (ISSN) ; Hosseinzadeh, M ; Zarepour Jevinani, M ; Ghanbari, B ; Sharif University of Technology
Royal Society of Chemistry
2017
Abstract
Two mononuclear coordination complexes of fullerene[60] with Pd(dba)2 (dba = dibenzylideneacetone), [(η2-C60)Pd(Ph2P(CH2)2PPh2C(H)C(O)R)2] (R = C10H7 (1), C6H4Cl (2)), have been prepared using a simple procedure to explore new directions in palladium catalysis and nanocarbon chemistry. The palladium(0)-[60]fullerene complexes incorporating unsymmetrical phosphorus ylides have been characterized by 1H, 13C and 31P NMR spectroscopic methods and other conventional techniques such as IR, TGA, SEM, ICP-OES, EDX and TEM analysis. Attributed to the enhanced dispersity and uniform size of the Pd nanoparticles with phosphine-functionalized fullerenes, the prepared catalysts exhibited comparable...
Reliability-Driven Approach for Controller Placement Problem in Software-Defined Networking
, M.Sc. Thesis Sharif University of Technology ; Movaghar Rahimabadi, Ali (Supervisor)
Abstract
Software Defined Networks has a centralized control layer for the network, so that the controller manages network on the basis of a global view of the network. Large-sized networks use multiple network controllers due to the possibility of single point of failure(SPOF) and distribute control tasks of the network between them. One of the challenges in these networks is how to place the controllers in order to increase network performance. Most of the work done in this field uses heuristic algorithms to solve the placement problems of controllers. The main weakness of the heuristic algorithms is that they are trapped in local optimal solutions. In this research, we used a hybrid genetic...
Performance analysis of carrier-less modulation schemes for wireless nanosensor networks
, Article 15th IEEE International Conference on Nanotechnology, 27 July 2015 through 30 July 2015 ; 2015 , Pages 45-50 ; 9781467381550 (ISBN) ; Hassan, M ; Chou, C. T ; Bayat, S ; Nanotechnology Council ; Sharif University of Technology
Institute of Electrical and Electronics Engineers Inc
2015
Abstract
Wireless Nano-scale Sensor Networks (WNSNs) are very simple and energy restricted networks that operate over terahertz band ranging from 0.1-10 THz, which faces significant molecular absorption noise and attenuation. Given these challenges, reliability, energy efficiency, and simplicity constitute the main criteria in designing communication protocols for WNSNs. Due to its simplicity and energy efficiency, carrier-less pulse based modulation is considered the best candidate for WNSNs. In this paper, we compare the performance of four different carrier-less modulations, PAM, OOK, PPM, and BPSK, in the context of WNSNs operating within the terahertz band. Our study shows that although BPSK is...
Applications and challenges of wearable visual lifeloggers
, Article Computer ; Volume 50, Issue 3 , 2017 , Pages 60-69 ; 00189162 (ISSN) ; Hosseini, M ; Kanhere, S. S ; Sowmya, A ; Rabiee, H. R ; Sharif University of Technology
IEEE Computer Society
2017
Abstract
Advances in the manufacturing of miniaturized low-power embedded systems are paving the way for ultra-lightweight wearable cameras that can visually log the minute details of people's daily lives. This survey highlights the possible applications of wearable cameras, from industrial to personal, and outlines the main challenges in realizing their full potential. © 2017 IEEE
Taking advantage of the coordinative behavior of a tridentate schiff base ligand towards Pd2+ and Cu2+
, Article Crystals ; Volume 9, Issue 8 , 2019 ; 20734352 (ISSN) ; Fondo, M ; Zarepour Jevinani, M ; García Deibe, A. M ; Sharif University of Technology
MDPI AG
2019
Abstract
We have explored the suitability of an O,N,N–donor Schiff base (H2SB) for obtaining dinuclear complexes with heavy metal ions such as Cu2+, Zn2+, Ni2+, and Co2+ (borderline acids) as well as Pd2+ and Cd2+ (soft acids). Spectroscopic studies demonstrated that the complexation of H2SB and Cu2+, Zn2+, Ni2+, Co2+, Pd2+, and Cd2+ occurred at a 1:1 stoichiometry. We have found two square planar centers with Pd-N-Pd angles of 93.08(11)◦ and a Pd–Pd distance of 3.0102(4) Å in Pd2(SB)2·Me2CO. This Pd–Pd distance is 30% shorter than the sum of the van der Waals radii, which is in accordance with a strong palladophilic interaction. Fluorescence studies on H2SB-M2+ interaction showed that H2SB can...
Exploring the chelating potential of an easily synthesized schiff base for copper sensing
, Article Crystals ; Volume 10, Issue 3 , 2020 ; García Deibe, A ; Zarepour Jevinani, M ; Aboal Somoza, M ; Bermejo Barrera, P ; Fondo, M ; Sharif University of Technology
MDPI AG
2020
Abstract
The present study deals with the investigation of Cu2+, Ni2+ and Pd2+ chelating potential of the Schiff base, (E)-N-(2-((2-hydroxybenzylidene)amino)benzyl)-4-methylbenzenesulfonamide (H2SB). Crystal structures of Ni(HSB)2, Pd(HSB)2 and Cu(HSB)2 have been elucidated from single crystal X-ray diffraction data. NMR spectroscopy showed the presence of two conformers of Pd(HSB)2 in solution, both with an E configuration of the ligand. The determination of binding constants by fluorescence quenching showed that affinity of H2SB to Cu2+ in solution is higher than for Ni2+ and Pd2+. Since there is a high demand for selective, sensitive, rapid and simple methods to detect copper in aqueous samples...
Exploration of an easily synthesized fluorescent probe for detecting copper in aqueous samples
, Article Dalton Transactions ; Volume 46, Issue 45 , 2017 , Pages 15827-15835 ; 14779226 (ISSN) ; García Deibe, A. M ; Fondo, M ; Zarepour Jevinani, M ; Domínguez González, M. R ; Bermejo Barrera, P ; Sharif University of Technology
Royal Society of Chemistry
2017
Abstract
An easily synthesized fluorescent probe for detecting copper in aqueous samples, with a short response time and at neutral pH, has been investigated. Through the chelation of Cu2+ ions or by binding to CuO nanoparticles, the fluorescence emission of the 2-(aminomethyl)aniline derivative H2L is quenched by over 50%. Spectroscopic determination of the association constants of H2L with some metal ions showed that the ligand has a higher affinity toward Cu2+ than toward other d-block metal ions. The comparative bonding ability of the aniline-based fluorescent probe in d-block metal complexes was studied in solution by a combination of UV-Vis, 1H NMR and mass spectrometry analyses. Besides these,...
Dose-dependent effects of nanoscale graphene oxide on reproduction capability of mammals
, Article Carbon ; Volume 95 , December , 2015 , Pages 309-317 ; 00086223 (ISSN) ; Ghaderi, E ; Hashemi, E ; Akbari, E ; Sharif University of Technology
Elsevier Ltd
2015
Abstract
In vivo dose-dependent effects of nanoscale graphene oxide (NGO) sheets on reproduction capability of Balb/C mice were investigated. Biodistribution study of the NGO sheets (intravenously injected into male mice at dose of ∼2000 μg/mL or 4 mg/kg of body weight) showed a high graphene uptake in testis. Hence, in vivo effects of the NGO sheets on important characteristics of spermatozoa (including their viability, morphology, kinetics, DNA damage and chromosomal aberration) were evaluated. Significant in vivo effects was found at the injected concentrations ≥200 μg/mL after (e.g., ∼45% reduction in sperm viability and motility at 2000 μg/mL). Observation of remarkable DNA fragmentations and...
Accelerated differentiation of neural stem cells into neurons on ginseng-reduced graphene oxide sheets
, Article Carbon ; Volume 66 , January , 2014 , Pages 395-406 ; Ghaderi, E ; Abouei, E ; Hatamie, S ; Ghasemi, E ; Sharif University of Technology
2014
Abstract
Asian red ginseng was used for green reduction of chemically exfoliated graphene oxide (GO) into reduced graphene oxide (rGO). The reduction level and electrical conductivity of the ginseng-rGO sheets were comparable to those of hydrazine-rGO ones. Reduction by ginseng resulted in repairing the sp 2 graphitic structure of the rGO, while hydrazine-rGO showed more defects and/or smaller aromatic domains. The ginseng-rGO sheets presented a better stability against aggregation than the hydrazine-rGO ones in an aqueous suspension. Whilst the hydrophobic hydrazine-rGO films exhibited no toxicity against human neural stem cells (hNSCs), the hydrophilic GO and ginseng-rGO films (as more...
Contested framings and policy controversies: Analysing biosafety policy-making in Iran
, Article Science and Public Policy ; Volume 40, Issue 5 , 2013 , Pages 616-627 ; 03023427 (ISSN) ; Millstone, E ; Sharif University of Technology
2013
Abstract
Vigorous debates have taken place within and between many countries about regulatory policy regimes covering the assessment and approval of genetically modified (GM) crops. In Iran, a very vigorous and hotly contested policy debate concerning legislation covering GM crops occurred between 2004 and 2009, but it was confined within government circles with almost no public discussion. This paper analyses the Iranian policy-making process in the period 2006-9. It explains how and why a stalemate arose in disputes between ministries and departments. The chosen analytical framework draws mainly on the regulation of technological risks and the analysis of public policy-making. It deploys the...
On the possible volumes of μ-way latin trades
, Article Aequationes Mathematicae ; Volume 63, Issue 3 , 2002 , Pages 303-320 ; 00019054 (ISSN) ; Billington, E. J ; Bryant, D. E ; Mahmoodian, E. S ; Sharif University of Technology
Birkhauser Verlag Basel
2002
Abstract
A μ-way latin trade of volume s is a set of μ partial latin rectangles (of inconsequential size) containing exactly the same s filled cells, such that if cell (i, j) is filled, it contains a different entry in each of the μ partial latin rectangles, and such that row i in each of the μ partial latin rectangles contains, set-wise, the same symbols and column j, likewise. In this paper we show that all μ-way latin trades with sufficiently large volumes exist, and state some theorems on the non-existence of μ-way latin trades of certain volumes. We also find the set of possible volumes (that is, the volume spectrum) of μ-way latin trades for μ = 4 and 5. (The case μ = 2 was dealt with by Fu,...
The three-way intersection problem for latin squares
, Article Discrete Mathematics ; Volume 243, Issue 1-3 , 2002 , Pages 1-19 ; 0012365X (ISSN) ; Billington, E. J ; Bryant, D. E ; Mahmoodian, E. S ; Sharif University of Technology
2002
Abstract
The set of integers k for which there exist three latin squares of order n having precisely k cells identical, with their remaining n2 -k cells different in all three latin squares, denoted by I3[n], is determined here for all orders n. In particular, it is shown that I3[n] = {0,.,n2 -15}U [n2 - 12,n2-9,n2], for n ≫8. ©2002 Eisevier Science B.V. All rights reserved
Integration of spatial fuzzy clustering with level set for segmentation of 2-D angiogram
, Article IECBES 2014, Conference Proceedings - 2014 IEEE Conference on Biomedical Engineering and Sciences: "Miri, Where Engineering in Medicine and Biology and Humanity Meet", 8 December 2014 through 10 December 2014 ; December , 2015 , Pages 309-314 ; 9781479940844 (ISBN) ; Zahedi, E ; Fatemizadeh, E ; Sharif University of Technology
Institute of Electrical and Electronics Engineers Inc
2015
Abstract
Coronary angiography is a vital instrument to detect the prevailing of vascular diseases, and accurate vascular segmentation acts a crucial role for proper quantitative analysis of the vascular tree morphological features. Level set methods are popular for segmenting the coronary arteries, but their performance is related to suitable start-up and optimum setting of regulating parameters, essentially done manually. This research presents a novel fuzzy level set procedure with the objective of segmentation of the coronary artery tree in 2-D X-ray angiography as automatically. It is clever to clearly develop from the early segmentation with spatial fuzzy grouping. The adjusting parameters of...