Sharif Digital Repository

The top quark is the heaviest of elementary particles. It gives the dominant contribution to the radiative correction to the Higgs self coupling constant which itself determines the structure of the electroweak vacuum. Therefore, it is extremely important to have a precise measurement of the top quark mass. On the other hand, whereas the lifetime of top quark is short and rapidly decays to lighter particles, it is not easy to compute and measure its mass with a desired precision. In this work, we propose a measurement method to determine the top quark mass in the t▁t→leptons +jets channel by analyzing the decay of the b-hadron in the top quark decay chain. Through the reconstruction of the... 

Nowadays, advanced and inexpensive pre-clinical methods for investigating the effects of anti-cancer drugs are expanding. One of the latest three-dimensional laboratory modeling for evaluating the effects of drugs is the use of tumor-on-chip technology, which actually models the physiological system of the body through three-dimensional scaffolds, multicellular cultures, and shaped vascular systems. In this study, three-dimensional culture of cancer cells was performed in the form of spheroids. A chip of U-shaped microstructures with and without gaps was used to trap cells and form cancer spheroids. We simulated the simultaneous effect of drug and oxygen concentration distribution inside the... 

Expansion of city boundaries as a result of increased population has reduced the distance from industrial complexes and health effects of industrial air pollution have been intensified. As such, studies are needed to determine appropriate methodologies for quantifying the effect of these industries on the concentration of air pollutants in urban areas. In this study, particulate emissions from a steel mill complex was modeled using ADMS4 and the predicted results were compared with actual measurements made in the adjacent urban area. A receptor model (CMB8.2) was also used to quantify the share of the steel mill on the heavy metals' concentrations in the city by considering other sources... 

Hazard analysis and risk assessment are the two significant methods of controlling and reducing risk caused by industrial units. To achieve the required safety needed in either new or operating plants, risk assessments are being used for some specific hazards such as fire, explosion and toxic release. Increasing industrial developments and occurrence of several catastrophic accidents in chemical processing plants have contributed to striking disasters and have obliged experts to use analytical solutions to evaluate frequencies and consequences of such events. Congested plants in industrial areas like Mahshahr and Asalouyeh in Iran and other places in the world are the reason why it has... 

The human speech conveys much information such as semantic contents, emotion and even speaker identity. Our goal in this thesis is the task of text-independent speaker identification (SI) in large population applications. Identification (test) time has become one of the most important issues in recent real time systems. Identification time depends on the cost of likelihood computation between test features and registered speaker models. For real time application of SI, system must identify an unknown speaker quickly. Hence the conventional SI methods cannot be used. The main goal in this thesis is to propose several methods that reduced identification time without any loss of identification... 

In this study design of controller for a nonlinear system in the presence of state observer was investigated. First, nonlinear observers including non-adaptive and adaptive versions and their design procedures were studied. Then nonlinear adaptive controllers, based on sliding mode, feedback linearization and back-stepping techniques were implemented in the presence of observer dynamics. Two versions of adaptive law were proposed for unknown parameters identification in feedback linearization and sliding mode techniques. A new adaptive law was proposed to relax the restrictive condition that is used in adaptive observer design. The closed loop stability of back stepping technique was studied... 

In this project, melamine formaldehyde was chosen as initial substrate for its high porosity. Then for having superhydrophobic surface, surface functional groups were silanized and deactivated as a result. It was assumed that high porosity of prepared sorbent and its nonpolar nature, can increase extraction efficiency. To study extraction efficiency of the prepared sorbent, it was filled inside a needle and used for needle-trap head-space extraction of BTEX (abbreviation for Benzene, Toluene, Ethylbenzene and Xylenes). Needle packed with sorbent was held on headspace of sample containing BTEX and head- space was pumped with a peristaltic pump. Pumping introduces fresh sample to sorbent... 

Speaker verification as a kind of biometric methods aims to verify the identity of a person from characteristics of their voice. This method faces many challenges such as voice imitation (spoofing), use of recorded voice, high sensitivity to convolutive distortions resulted by channel, and a large performance degradation for short-duration utterances. The aim of this thesis is to propose different methods for reducing the effects of non-identity information,especially the channel, and also solving the problem of new methods for text-dependent speaker verification with very short utterances. i-vector has been the best speaker modeling method in recent years but it doesn’t result in good... 

Deligne Proved that cohomology groups of algebraic varieties over C have mixed Hodge structures.It is also proved that homotopy groups of these varieties have mixed Hodge structures in a proper sense.In this thesis using iterated integrals that introduced by Chen,we explain Hain’s approach for defining Hodge structures on truncated first homotopy groups(fundamental groups). Note that there is another approach for defining Hodge structures on homotopy groups by Morgan,that uses minimal models of Sullivan.For explaining Hain’s approach,some basic results on Hodge structures are also explained  

The main focus of this thesis is based on surface modification of polystyrene in order to prepare extractive phases appropriate for extraction of analytes with a wide polarity range. This goal was achieved by increasing surface polarity. In fact, improved wettability and the possibility of interaction with polar analytes after addition of functional groups on polystyrene surface were the main reason for increased extraction capacity. In the first research, different functional groups including amine, nitro, carboxyl and acetyl were added on polystyrene particles by chemical bonding and to investigate their influence on extraction process, 22 analytes with a wide polarity range (LogP=-2 to... 

The purpose of this study is to propose a stable treatment strategy for hepatitis C infection by considering several practical limitations of the treatment and using control theories. First, hepatitis C disease and its transmission, diagnosis, and treatment methods have been introduced. Then, the mathematical models of hepatitis C dynamics in the body have been presented, and their ability in predicting the observed clinical behaviors of the patients has been studied. Thereafter, the extended versions of these models by considering pharmacokinetics/dynamics equations of the drugs have been proposed to have a more realistic mathematical model. After that, the practical features of the disease... 

Modeling and performance evaluation of the real time distributed systems is a significant problem. Stochastic activity network is one of the high level models used for this purpose. This network is an extension of generalized stochastic Petri net which is more powerful and flexible than other Petri net extensions. Checking the satisfiability of properties such as performance, dependability and user's expected properties is considerable in these models. Thus, using the approaches and generating modeling and model checking tools with the mentioned purpose is attractive. A model checker automatically checks the correctness of the system behaviors as properties against the model by getting the... 

Cardiovascular diseases are among the leading causes of death worldwide. For instance, in 2015, almost 31% of the world’s mortality rate was due to these causes. One of these diseases is cardiac coronary vessels’ occlusion which leads to the insufficient blood supply to the heart tissue and cardiomyocytes death after Myocardial Infarction (MI). After MI, a hierarchy of events in the heart tissue changes heart muscle and forms cardiac fibrosis. This fibrotic tissue does not have the native one’s properties and function, so it will cause cardiac arrest and patient death. Therefore, it is obvious that vascular network plays a crucial role in the heart function. The importance of cardiac... 

This study has focused on the important problem of landing on a planet as an important current and future space mission. In this regard, dynamics modeling and integrated state estimation and control problems have been investigated in different views. To this aim, first a novel concurrent representation for translational and rotational kinematics has been developed based on the extension of modified Rodrigues parameters to dual space. This parameter set, called dual modified Rodrigues parameters (DMRP), is then utilized to establish an integrated roto-translational dynamic. The proposed DMRP-based kinematics and dynamics have been verified via comparison to traditional methods of... 

This thesis addresses the problem of optimal distributed control of unknown interconnected systems. In order to deal with this problem, a data-driven learning framework for finding the optimal centralized and the suboptimal distributed controllers has been developed via convex optimization.First of all, the linear quadratic regulation (LQR) problem is formulated into a nonconvex optimization problem. Using Lagrangian duality theories, a semidefinite program is then developed that requires information about the system dynamics. It is shown that the optimal solution to this problem is independent of the initial conditions and represents the Q-function, an important concept in reinforcement... 

Accurate and fast attitude estimation of a rigid body plays an essential role in the performance of a vehicle’s control system, especially aerospace vehicles. Ample works have been done to increase the accuracy and speed of the attitude estimation process, but all have been developed according to a model-based approach. This approach assumes that the torques acting on the body have a known dynamical model that is used for the attitude estimation. The purpose of the present research is to estimate the attitude via a model-free approach, i. e. dynamics of the torques acting on the body are no longer assumed to be known, and its learning is the next step. Thus, the problem formulation of this... 

This thesis presents a new approach to design structural output feedback controllers with stabilization and pole-placement at desired points on the S plane. It is assumed that the linear time-invariant system has no fixed mode corresponding to the specified control structure, outside the desired region of the closed-loop poles, such that the structural controller design problem is theoretically feasible. To this end, the structural output controller design problem is first transformed into a structurally equivalent problem based on the solution of a set of discrete linear programs. Then, by using the resultant structure, a new method is proposed for designing static and dynamic control loops... 

Cardiovascular disease (CVD) currently remains a considerable challenge for clinical treatments. CVDs account for N17.5 million deaths per year and will predictably increase to 23.6 million by 2030. The main purpose is to create human model systems to study the effect of disease mutations or drug treatment on the heart. In addition, engineered cardiac tissues are considered promising candidates to be transplanted to improve the function of diseased hearts. For engineered active tissues/organs, 3D bioprinting can fabricate complex tissue architecture with a spatiotemporal distribution of bioactive substances (cells, growth factors, and others) to better guide tissue regeneration. However,...