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antibacterials
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Non-Scratch, Antibacterial And Self-cleaning SiO2/TiO2 Nano Composite Coating on Surgical Tools By Sol-Gel
, M.Sc. Thesis Sharif University of Technology ; Ghorbani, Mohammad (Supervisor)
Abstract
In this study TiO2/SiO2 thin films were prepared by sol-gel method from Tetra isopropylortho Titanate(TIPT) as the principle of TiO2 material with Tera ethoxysilane(TEOS) as the principle of SiO2 material to achieve high scratch-resistant , antibacterial and self-cleaning surface area under the effect of various percentage of SiO2 . Film deposition was carried out using a dip-coating technique and heat-treatment was used at 700ºC to achieve crystalline of films with excellent adherence the of substrate.
The surface morphology of the films has been observed by Scanning Electron Microscope (SEM) and the tribological properties of the surface were investigated by Atomic Force Microscope...
The surface morphology of the films has been observed by Scanning Electron Microscope (SEM) and the tribological properties of the surface were investigated by Atomic Force Microscope...
Synthesis of ZnO and ZnO-TiO2 Nanocoatings by Sol-Gel Methode and Study in Their Antibacterial and Photocatalyst Properties
, M.Sc. Thesis Sharif University of Technology ; Dolati, Abolghasem (Supervisor)
Abstract
The goal of this study is synthesis of nanocoating on basis of ZnO by Sol-Gel method and evaluation of their antibacterial and photocatalyst properties changes by different values of TiO2. For this purpose in both method of synthesis contents of TiO2 hase been changed from 0-25 molar percent. Dip coat method has been used for coating from sol with 1.4 mm/s withdrawal speed and 2 minute immersion time. After each step of coating samples has been dried at 150oC for 10 minute and for increasing thickness this process has been repeated 4 times. In first method zinc acetate dihydrate in 0.1 M final concentration and titanium tetraisopropoxide are sol precursors at in situ way of synthesis. In...
Ways to Detect Dounterfeit Honey
, M.Sc. Thesis Sharif University of Technology ; Alemzadeh, Iran (Supervisor)
Abstract
Honey as a food product with plant origin that nearly ninety percent of its dry weight is composed of sugars (mostly fructose and glucose) which has many food and pharmaceutical properties. So honey quality strongly depends on bees feeding practices. For this reason common indexes is defined generally are on the basis of hony composition, for example fructose and reducing sugar portion must be at least thirty and sixty-five percent respectively of total weight or sucrose percent must be utmost five and otherwise puts into question honey quality. To check the quality of five honey samples taken from the market, indexes such as water content, sugar composition(fructose, reducing and total...
Fabrication and Characterition of Flour Bearing Fibroin/ Nano-TiO2 Biodegradable Nanocomposite for Bone Tissue Engineering
, Ph.D. Dissertation Sharif University of Technology ; Maddah Hosseini, Hamid Reza (Supervisor)
Abstract
It is known that Fluoride ions strongly affect bone mineralization and formation. In the present study, the engineered bone tissue scaffolds are fabricated using silk fibroin (SF) and flouridated TiO2 nanoparticles. TiO2 nanoparticles are modified by fluoride ions, and different levels (0, 5, 10, 15 and 20 wt.%) of the fluoridated TiO2 nanoparticles (TiO2-F) were subsequently added to the SF matrix through phase separation method to prepare silk fibroin/flouridated TiO2 nanocomposite scaffolds (SF/TiO2-F). Phase structure, functinal groups, morphology and mechanical properties of the obtained scaffolds were evaluated by X-ray difraction method (XRD), Fourier transform infrared spectroscopy...
Comparing Effects of Natural Antibiotics and Anti Bacterial Materials in Burn Wound Infections with Nanoparticles and Skin Scaffold
, M.Sc. Thesis Sharif University of Technology ; Alemzadeh, Iran (Supervisor) ; Vosoughi, Manouchehr (Supervisor)
Abstract
Burns are one of the most important accidents related to human health. Due to the intense physical and mental complications and high fatality rate associated with them, receiving proper treatment is of paramount importance. The control of infection in wounds would cure and eliminates the effect of wounds and treatment of skin lesions with engineered scaffolds can be an effective method. The purpose of this project is proposing a hydrogel scaffold based on natural polymers of oxidized alginate and gelatin loaded with an herbal drug to control infection and treat burn wounds. For this purpose, the Iranian Oak extract that it's main content is Tanin and PolyPhenolinc materials, was prepared and...
Synthesis of Antibacterial Hydroxyapatite/Titania-Silver Coating on Titanium Substrate Using Sol-Gel Method
, M.Sc. Thesis Sharif University of Technology ; Afshar, Abdollah (Supervisor)
Abstract
With the increase in the average age of the world's population, osteoporosis is a worldwide incidence. This disease, along with natural disasters, are important factors in the occurrence of fractures in various bones of the body. One of the methods for solving this problem and replacing with broken body bones is the use of metal implants with hydroxyapatite-based coatings. One of the common problems with using implants in the body is the infection in the adjacent parts of the implant. To overcome this problem, several studies have been carried out on the use of hydroxyapatite coatings with metal ions or antibacterial oxide compounds. In the present study, the influence of factors such as the...
Studying Graphene Oxide Nanoflakes Size Effect on Antibiotic Resistant Bacteria
, M.Sc. Thesis Sharif University of Technology ; Naseri, Naimeh (Supervisor)
Abstract
Two-dimensional (2D) nanomaterials are ultrathin nanomaterials with a high degree of anisotropy and chemical functionality. Research on 2D nanomaterials is still in its infancy, with the majority of research focusing on elucidating unique material characteristics and few reports focusing on biomedical applications of 2D nanomaterials. Here we report the properties and application of 2Dnanomaterials in field of bio technology while used main material in our project is graphene oxide for investigating its antibacterial properties. Because the properties of graphene oxide (GO)-based materials strongly depend on the lateral size and size distribution of GO nanosheets; therefore, GO and its...
Synthesis and Preparation of Nanostructured Ag@SiO2 Core Shells with Different Morphologies and their Antibacterial Properties
, Ph.D. Dissertation Sharif University of Technology ; Halali, Mohammad (Supervisor)
Abstract
In this study, silver nanoparticles (Ag NPs) with different morphologies were synthesize by physical and chemical methods. Spherical silver nanoparticles were synthesized by electro magnetic levitation melting approach, while silver nanoplates and nanorods were prepared by chemical reduction route. Ag NPs were then coated with thin porous silica shell. The dissolution behavior of synthesized Ag@SiO2 was investigated in PBS at 25, 37 and 55 °C. Spherical and triangular Ag@SiO2 were conjugated by Penicillin G molecules. The silver and penicillin contents of the synthesized nano-antibiotics were determined by ICP-OES and TGA analyses. The nanoparticles were characterized by X-ray diffraction...
Synthesis and Experimental Study of Organic-Metal Framework (MOF) Nanophotocatalists with Antibacterial Properties
, M.Sc. Thesis Sharif University of Technology ; Vossoughi, Manouchehr (Supervisor) ; Abdi, Jafar (Co-Supervisor)
Abstract
MOFs are new class of materials that are used in different scientific fields because of their hybrid structure. In this project, focused on two specific applications, and aim is synthesis of a nanostructure which has antibacterial and photocatalytic activity. ZIF-8 because of its chemical and physical stability has been studied. For improving antibacterial influence and photocatalytic activity, silver nanoparticles are added to the structure. Magnetic nanoparticles covered by silica were used as core to facilitate separation process, ZIF-8 structure was constructed as shell on SiO2@Fe2O3 nano spheres. Magnetic nanoparticles improving stability of ZIF-8 in aqueous solutions. Synthetic nano...
Fabrication and Characterization of Bioactive PLGA- TiO2 Nanocomposite Scaffold by Air-liquid Foaming for Bone Tissue Engineering
, Ph.D. Dissertation Sharif University of Technology ; Madaah Hosseini, Hamid Reza (Supervisor) ; Samadi Kuchaksaraei, Ali (Co-Supervisor)
Abstract
Poly (lactate-co-glycolate) is a typical biocompatible and biodegradable synthetic polymer. Addition of TiO2 nanoparticles improved compressive modulus of PLGA scaffolds and reduced fast degradation. Porous 3D scaffolds, which are synthesized using biocompatible and biodegradable materials, could provide suitable microenvironment and mechanical support for optimal cell growth and function. A novel method has been applied to fabricate PLGA/TiO2 scaffolds without using any organic solvent or porogen for nucleation compared to former ways, with aim of improving the biocompatibility, macroscale morphology and well inter-connected pores efficacy: Air-Liquid Foaming. Adjustment of the foaming...
Synthesis, Characterization and Applications of Antibacterial Metal-Organic Framework Nanocomposites for Water Remediation
, M.Sc. Thesis Sharif University of Technology ; Borghei, Mehdi (Supervisor) ; Yaghmaei, Soheila (Supervisor) ; Ghobadi Nejad, Zahra (Co-Supervisor)
Abstract
Contaminants in drinking water, including microbial contaminants, have a great impact on the health of people in the community and can seriously threaten public health. In recent years, diseases caused by pathogenic bacteria due to the consumption of contaminated water have led to many deaths. As a result, water treatment has been one of the most important human concerns. Among the new water treatment technologies, metal-organic(MOF) frameworks are a new generation of porous materials that have properties such as high surface area, water stability and functionality due to their dual structure. As a result, they are widely used today in various scientific fields, including water purification....
Synthesis of Antibacterial Nanoparticle for Packaging Food Application
, M.Sc. Thesis Sharif University of Technology ; Yaghmaei, Soheila (Supervisor) ; Ghobadinezhad, Zahra (Co-Supervisor)
Abstract
Food spoilage cased by food-borne pathogens and microorganisms is a serious problem in the food and packaging industry. Then, the demand for antibacterial agents in food packaging is growing. The antibacterial efficacy of some nanocomposites has been recognized and exploited in various industries, including the packaging industry. Also, metal organic frameworks due to their porous structure, are used in various fields such as food packaging. The purpose of this work, is synthesize hybrid nanocomposite that have promising antibacterial activity for preparation of food packaging films. Carboxymethyl cellulose is a derivative of cellulose fiber. The use of carboxymethyl cellulose as...
Design and Optimization of Hydrofiber Dressings Containing Borosilicate Bioactive Glass Doped with Zinc for Wound Healing
,
M.Sc. Thesis
Sharif University of Technology
;
Mashayekhan, Shohreh
(Supervisor)
;
Karimi, Afzal
(Supervisor)
Abstract
Wound healing is a complex and regular process. It makes more challenge when the volume of wound exudate becomes uncontrollable. To solve this problem, hydrofiber wound dressings which contain carboxymethyl cellulose fibers are being used. Fast absorption and keeping the moisture in balance specially in chronic wounds, is one of the major features of hydrofiber wound dressings. In this research, which was conducted with the aim of investigating the synergy effect of active glasses and Hydrofiber commercial wound dressing for the healing of skin wounds, especially chronic wounds, the sol-gel method has been used to synthesize bioactive glasses based on borosilicate, replacing a part of CaO...
Fabrication and Characterization of Antibacterial Properties of Electroceutical Wound Dressings Containing Silver and Zinc Oxide Nanoparticles
, M.Sc. Thesis Sharif University of Technology ; Pircheraghi, Gholamreza (Supervisor)
Abstract
The World Health Organization's annual statistics show that 83% of wounds are caused by bacterial infections. Diabetic ulcers affect approximately 28 million people worldwide. The use of antibacterial dressings can help control infections. Recent studies have found that electrical stimulation can accelerate wound healing. However, there is still a need for interventions that speed up epithelial tissue formation. New dressings with zinc and silver particles that have electrical activity are being developed, but research on these methods is limited. Zinc oxide nanoparticles have been used as antibacterial agents due to their unique surface properties. This research aims to use these...
Produce of Antibacterial Composite Coating of PTFE+Ag+TiO2 On 316SS and Study Its Properties
, M.Sc. Thesis Sharif University of Technology ; Afshar, Abdollah (Supervisor)
Abstract
This research investigated the corrosion and antibacterial properties of PTFE+TiO2/Ag coating and its adhesion to 316L stainless steel. To increase adhesion, polydopamine coating was created as an intermediate layer by chemical deposition method on stainless steel, then PTFE + TiO2 coating was created on the sample by immersion method, and then silver nanoparticles were applied as the third layer by chemical deposition method. According to the polarization curves, the most corrosion-resistant coatings with corrosion current density of 3.34×10-5 and 3.25×10-4 μA are coatings PTFE+TiO2 and PTFE/PTFE+TiO2/Ag respectively. In terms of antibacterial activity, according to the non-growth halo...