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Preparation a Bio-Composite Scaffold Containing Hydroxyapatite/Silver Faunctionalized Graphene Oxide/Chitosan for Bone Tissue Engineering
, M.Sc. Thesis Sharif University of Technology ; Nemati, Ali (Supervisor) ; Malek Khachatourian, Adrineh (Supervisor)
Abstract
Bone scaffolds are used to regenerate bone tissue and accelerate bone healing, for this purpose, an attempt was made to prepare biocompatible, biodegradable, low toxicity and non-allergenic scaffolds to help increase osteogenesis and improve bone infections. A porous multi-component composite of chitosan, hydroxyapatite, graphene oxide functionalized with silver was made to make the desired scaffolds. At first, graphene oxide was functionalized by silver ions using silver nitrate. The structure of silver graphene oxide nanocomposite was confirmed by scanning electron microscope (SEM), Fourier infrared spectroscopy (FT-IR), and ultraviolet (UV-Visible) spectroscopy. In the next step, a...