Sharif Digital Repository

Effective parameters on decolourization of Sumifix Black B or Reactive Black 5 (RB5) by the extracted peroxidase from Coprinus Cinereus NBRC 30628 in a bioreactor have been reviewed in this master thesis. These parameters were such as hydrogen peroxide concentration, pH of dye solution, enzymatic activity and hydraulic retention time. All of these parameters were optimized in such condition that enzyme solution was added to bioreactor at the initial time of reaction. Optimum concentration for hydrogen peroxide, pH, dye concentration, and hydraulic retention time in above mentioned condition of reactor were 96.1 mM, 8, 40 ppm, and 60 min, respectively. It is worth to note that the higher... 

TPPB are characterized by a cell-containing aqueous phase, and an immiscible and biocompatible organic phase that partitions toxic/insoluble substrates to the cells base on their metabolic demand and the thermodynamic equilibrium of the system. Surface areas, Mass transfer coefficient, Hydrophobicity of polycyclic aromatic hydrocarbons (PAH) are considered as limitation in two phase partition bioreactors (TPPB). For solving of this challenge, in this project used solid particle for increment of mss transfer and surface area, and also solid particles can eliminate limitation of initial concentration of polycyclic aromatic hydrocarbon and ratio of aqueous/organic phases. Naphthalene is used as... 

In this thesis, a bioreactor with oscillatory and chaotic behavior has been studied and a control method has been proposed. This bioreactor shows oscillations for some special values of its parameters. The system dynamic is chaotic when a forced perturbation on the feed concentration is imposed. Dynamic behavior of this oscillatory and chaotic reactor has been illustrated. The main objective is control of product concentration. To do this, first system control is considered by proposing several control strategies for SISO case, then system in MIMO case is studied for achieving a globally controllable system. In SISO case, the performances of controllers are compared based on an objective... 

Recovery of heavy metals from Hydrocracking spent catalyst was studied in a bioreactor by Acidithiobacillus thiooxidans. At first adaptation of microorganisms was done with spent catalyst in shaker flask. Using central composite design (CCD) the experiments were conducted in order to find optimized condition. Three factors such as particle size, pulp density and aeration rate were examined. Reduced cubic models were established to identify the relationship between the recovery percent of the metals and the variables. The results showed the maximum extraction of 87% Mo, 37% Ni and 15% Al were achieved after 7 days of batch process in bioreactor. The optimal values of variables were pulp... 

Recently experiences in chemical processes approved that periodic operation for some of the processes (e.g. ion exchangers, activated sludge tanks, etc) were being successful. The performance and/or effectiveness of process due to periodic changes in the systems input, such as concentration, feed or coolant temperature and other possibilities, typically express whether in term of yield or selectivity improvement. Though, prominent issue in this type of dynamical control problem is optimal frequency and amplitude in the cycle. Supporting mathematics, include two main approaches: (1) the Hamilton-Jacobi approach based on the maximum principle and (2) a frequency domain approach using second... 

The goal of this project is finding an appropriate method for controlling four different bioreactors with unknown dynamics. At first, an introduction to bioreactor dynamic hase been presented, then their nonlinear behavior has been discussed. In the following, four output control systems using adaptive neural network have been designed separately for four different dynamics. The applied control method has been adapted from a method of references with some changes. Performances of designed controllers in set point tracking, load rejection and model mismatch have been evaluated using simulation. In these studies, input saturation has been considered in simulations but it is not existed in... 

Control of fermentation bioreactors with nonlinear behavior is a very important issue, especially when optimizing the biomass production is desired. The system in this situation works in two domains: minimum phase and non-minimum phase; and in transition from one domain into the other one the sign of process gain changes. For control of such a process in this work have been used two non-adaptive strategies and one adaptive strategy. The non-adaptive schemes are pole-placement and model predictive. The pole-placement technique as a linear control algorithm is used and its parameters are fixed by minimizing the objective function which has been used in predictive control technique. Another... 

Biotechnology is one of the fields that has had great advances in the past decades, and therefore controlling biological processes (bioreactors) is considered as an important issue. The purpose of current thesis is designing an adaptive controller for a bioreactor by considering input constrain and proving the stability of closed loop. A standard bioreactor has been chosen for this purpose. First a non-adaptive controller has been designed. Then an adaptive controller is designed and implemented on a bioreactor in the presence of input constraint, because in practice the system parameters are unknown. Finally by applying disturbance to the system, it has been shown that the proposed control... 

In present study, two bioreactors for biological and chemical removal of nitrogen oxides are modeled. Nitrogen oxides are of the most important pollutants in flue gas stream. These components are hazardous materials and could lead to acid rain, ground-level ozone, smog and the depletion of ozone layer. There are several methods for removing these pollutants which are categorized to two main groups: non-biological and biological methods. Biological removal has the advantage of removing the pollutants by an acceptable efficiency. In present study, two packed-bed bioreactors are modeled by the means of considering two kinds of biological removal mechanism in defined operating conditions. The... 

Discharging treated or raw waste water in to surface water may cause lots of serious problems, including growth of algae, as a result of the presence of nutrients in waste water.algae decrease the concentration of dissolve oxygen in water.phosphorus removal from waste water is of absolute necessity. according to the standards set by the environmental organization, discharge the untreated waster water in to the surface water is not allowed. on the other hand, given manager facilities of deprived area,effort is channeled to reach the desired result through designing the simplest treatment systems. anaerobic-aerobic systems have remarkably been used for many years in the treatment of urban and... 

Myocardial infarction (MI) is one of the diseases caused by the temporary or permanent cramp of major coronary arteries. Due to this blockage, blood flow to the heart's myocardial tissue is greatly reduced and finally the person suffered from a Heart stroke (HS). Heart tissue engineering is a promising approach, based on the combination of cells and suitable biomaterials to develop and create heart-like biological substitutes. Since high cardiac cell density, providing metabolic needs like oxygen and nutrients was a challenge. So creation of blood vessel networks within this type of designed tissue has been considered very much.The purpose of this project is to construct scaffolds with... 

Among all electornical wastes, printed circuit boards (PCBs) of mobile phones and computers has more share than other e-wastes. E-wastes contains toxic and maybe worthable metals like copper, nickel, gold, silvet and etc. In this project, ability of Penicillin Simplicissimum in bio-leaching of copper and nickle in mobile phones PCBs, is studied. Daily production of this kind of e-wastes, requires an industrialized and economical method to help the environment. At the first step of this project, the fungi was adapted to e-waste. Then, optimization of pH and number of spores in inoculum of bioleaching by Penicillin Simplicissimum in non-conventional mediums (sugar, cheese water and molasses)... 

Due to advances of biotechnology, control of bioprocess has become very important. The goal of this project is to simulate the acetic acid production bioreactor and designing an adaptive PI controller for this reactor. For this goal, a suitable model has been selected from the literature and simulation has shown that the system has a nonlinear dynamical behavior. In order to control the system in a wide range of operating conditions, the adaptive PI controller was designed. In single input-single output case, the concentration of the product is controlled in such a way that the production rate is maximized, assuming that the pH and temperature are kept constant. Then a two input-two... 

Dynamic modeling and process control, especially the equipment of bioreactors and fermenters, have always faced many challenges due to the complexity and high uncertainty of the kinetics of environmental reactions. Among these, semi-continuous fermentation for bioethanol production is one of the important technologies in biochemical industries. The problem of modeling as well as controlling the use of the main discontinuous and semi-continuous methods of ethanol production is the lack of uniform state conditions and the possibility of aerobic and non-aerobic multiplication conditions in two ways. The main goal of this research is to obtain a new method in modeling bioethanol fermentation and...