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carboxamides
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QSAR Study of Chromenes & Carboxamides as Anti-Breast Cancer Drugs
, M.Sc. Thesis Sharif University of Technology ; Jalaly Heravi, Mahdi (Supervisor)
Abstract
Breast Cancer is considered one of the most common cancers among Iranian women. Every year, seven thousands women start suffering from this disease. Since 70 percent of this patients live over 5 years, after this disease starts, there are 70 thousands women who are suffering from the cancer. The average age of getting the disease in Iran is 5 years lower than that of the global level. Studies show that compound containing Chromene and Carboxamides are appropriate candidates for preventing breast cancer. One of the most important fields of researches in Chemistry and Bio-Chemistry is QSAR which is used to relate the structure of molecules to their activities. In this study, molecular...
Synthesis and Characterization of Transition Metal Complexes with Carboxamide Ligands and Nanostructures for Catalytic and Antibacterial Activites Application
, Ph.D. Dissertation Sharif University of Technology ; Bagherzadeh, Mojtaba (Supervisor)
Abstract
Carboxamide ligands have been part of the growing research in the field of coordination chemistry of transition metal complexes. The solvent used in the classical method of synthesis of these compounds is pyridine, a solvent which is extremely toxic. In this project, we have developed a new method of synthesis using ionic liquids as the reaction media and have prepared Hqcq (1), Htp(2) under optimum conditions for Pd(II) and Pt(II) complexes of Hqcq and Co(II), Cu(II), Zn(II), Cd(II) and Hg(II) complexes of Htp with the formula:[Pd(qcq)(OAc)] (1a), [Pt(qcq)(Cl)] (1b), [Co(Htp)2(H2O)2].C2H5OH (2a), Co3O4 (2b), [Cu(tp)2(H2O)].CHCl3 (2c), CuO (2d), [Zn(tp)2(H2O)2] (2e), [Cd(tp)2(H2O)2].CH3OH...