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    Designing Electrophysiological Characterization System of Biological Cells Based on the Use of Nanostructured Electrodes

    , Ph.D. Dissertation Sharif University of Technology Vafaiee, Mohadeseh (Author) ; Vossoughi, Manouchehr (Supervisor) ; Sasanpour, Pezhman (Supervisor) ; Mohammadpour, Raheleh (Supervisor)
    Abstract
    In the last half century, the recording of the electrophysiological activities of the neurons has been one of the most effective methods for neuroscience development. One of the techniques used to record the activity of the nerve cells is the use of multi-electrode arrays (MEAs). Current MEAs still face limitations such as low signal-to-noise ratio (SNR) and low spatial resolution. There is a need to develop arrays that are smaller in size and have less impedance to achieve better spatial resolution and lower noise levels. The main focus of this research is on the designing and fabrication of multi-electrode arrays and improvement of their properties using nanostructures and conductive...