Design and Optimization of Digital Microfluidic Chip for Cell Sorting

, M.Sc. Thesis Sharif University of Technology Orouji, Nooshin (Author) ; Fardmanesh, Mehdi (Supervisor)

Abstract

Today, microfluidics, representing the precise and controlled displacement of small amounts of fluid, is one of the most efficient tools available in various research fields, including medicine. Digital microfluidics is one of the newest microfluidic methods, which is based on the theory of electrowetting on dielectric. According to this theory, by applying a voltage difference to a droplet of fluid on a hydrophobic surface, the droplet can be moved on that surface. Therefore, by fabricating a plate containing a number of electrodes completely isolated from each other and controlling them, small droplets of fluid can be moved on a hydrophobic surface. In this thesis, the electrodes of this...

Design and Simulation of an Electrowetting Micro-Pump

, M.Sc. Thesis Sharif University of Technology Ebrahimi, Amin (Author) ; Javadi, Khodayar (Supervisor)

Abstract

Micropumps are one of the most important devices in the field of microfluidics which have many applications in various fields of engineering. Electrostatic excitation is one of the types of excitation mechanisms in micropumps that is widely used in microelectromechanical systems due to its low power consumption and easier control. In this research, first, the physics of droplets on the surface studied, important dimensionless numbers and other factors influencing microfluidic phenomena are investigated. The effective parameters of the droplet motion and the mechanism of this motion are described. Besides, the phenomenon of electrowetting, one of the phenomena in the field of dynamics of...

The Numerical Simulation of Droplet Generation and its Control Using Electrowetting Method in Microfluidic Devices

, M.Sc. Thesis Sharif University of Technology Merdasi, Arshia (Author) ; Moosavi, Ali (Supervisor) ; Shafii, Mohammad Behshad (Supervisor)

Abstract

In this research, two important mechanisms were discussed including droplet generation and jumping mechanisms using electro wetting-on-dielectric. For these purposes, the finite element method (FEM) was used to solve the unsteady Naiver-Stokes equation. In addition, the level set method was applied to capture the interface between two phases. In the current study, first, droplet generation in a T-junction fluidic channel device was studied through using electro wetting actuation. The efficacy of electro wetting on the droplet generation frequency as well as droplet diameter is visible in a T-junction fluidic channel since after applying voltages, specified with non-dimensional electro...