Sharif Digital Repository

Nowadays counting small particles and gathering their morphological information is widely used in many fields as medicine, engineering, etc. One of the best examples of this technology is counting and distinguishing different cells which are considered bioparticles. In this thesis a brief review of different particle counting methods is presented. Among these methods flow cytometry technology is chosen, because of its speed and accuracy. In flow cytometry method cells are conducted to the center of a transparent capillary by sheath flow technique; then laser beam is radiated to the cells. The intensity of the light scattered from the cells is used to determine cell type and count. In... 

Microfluidics is the science of fabricating systems interfacing fluids of small volume and size ranging from microliters (10-6) to picolitres (10-12). Due to its remarkable features, such as low sample and reagent consumption, high sensitivity, low cost, automated devices, and short experimental time, microfluidic chips have been widely used as laboratory assays. As a term often used and described in “lab on a chip” and “organ on a chip” technologies, microfluidic chips have been used in the fast and frugal diagnosis of infectious diseases such as HIV, microscale surgery on single cells and tiny organisms and cell culture.The design, simulation, optimization, and fabrication of an... 

Microfluidic technology is a field of science that deals with the design, implementation, optimization, and testing of fluid systems in small dimensions. This technology has made significant progress in various fields in the last decade, especially in medical engineering. As an interdisciplinary scientific field, this growing technology has many applications in medicine, pharmaceuticals, chemistry, and electronic industries. One of the primary applications of microfluidic devices is the development of "lab-on-a-chip" systems as point-of-care diagnostic tools, such as rapid diagnosis during surgery. A microfluidic system includes various functional modules: sample preparation and fluid... 

Microfluidic technology is a field of science that deals with the design, fabrication, and experimental tests of small-scale fluid systems and has made great strides over the past decade. As an interdisciplinary field, this growing field of technology has many applications in medicine, diagnostics, chemical analysis, electronics industry, etc. One of the primary applications of the microfluidic devices is the development of " laboratory on-chip (LOC)" tools as point-of-care (POC) diagnostic tools, such as, rapid detection during surgery. A LOC device includes various application modules, sample transfer and preparation modules, separation modules, and detection and analysis modules. The...