Sharif Digital Repository

Considering principles of both micro-solid phase extraction (µ-SPE) and stir-bar sorptive extraction (SBSE) techniques, in this study a microextraction technique was developed using a polypropylene sheet as extracting device for isolation of fluoxetine from biological samples. Being rather inexpensive and simple to prepare extracting device, elimination of time consuming sorbent synthesis step and memory effect are some of the advantages of the proposed method. The extraction process was performed using a polypropylene sheet as extracting device. Solvent desorption was performed in a microvial and then extractant was injected into HPLC system. The effect of various parameters including pH,... 

In this study new magnetic solid phase extraction (MSPE) methods based on Fe3O4 magnetic nanoparticles (NPs) for extraction and preconcentration of oxadiargyl and fuoxetine from aqueous and biological samples were developed. In the first work, Fe3O4 NPs was successfully used as a magnetic nano-sorbent in magnetic micro-solid phase extraction (M-µ-SPE) of oxadiargyl, a newly used pesticide, from environmental water samples prior to gas chromatography-mass spectrometry determination. Oxadiargyl in mild acidic condition has tendency to be adsorbed on Fe3O4 NPs surfaces. Most important parameters that affect the extraction efficiency were also studied. Under optimized condition, the proposed... 

This thesis contains two major sections. The first section is dealing with the preparation of conductive polymers-based sorbents while the second section is mostly focused on the synthesizing nanocomposites by electrospinning. All the prepared sorbents and nanofibers have been utilized to isolate some organic compounds in environmental and biological samples. Section I:In the first chapter, an unbreakable solid phase microextraction fiber coating based on aniline-silica nanocomposite was electrodeposited on a stainless steel wire. The electropolymerization process was carried out at a constant deposition potential, applied to the corresponding aqueous electrolyte containing aniline and...