Environmental Monitoring of Formaldehyde in Biologics Production Areas Using Solid-Phase Microextraction Coupled to Gas Chromatography Mass Spectrometry

, M.Sc. Thesis Sharif University of Technology Allahdad Lalouni, Misagh (Author) ; Bagheri, Habib (Supervisor) ; Eshaghi, Ali (Supervisor)

Abstract

During the recent years, manufactures and industries have paid attention to occupational health and safety of their employees. Formaldehyde is known as a probable carcinogenic agent and its large consumption made industries to consider it as a risk factor for occupational health. At vaccine production industries, Formaldehyde is used as disinfectant and stabilizer. In this study, a solid-phase microextraction (SPME) method based on kinetic and equilibrium calibration strategies was developed for monitoring of formaldehyde in the biologics production areas. The application and feasibility of three different sol-gel based SPME fibers with different polarities have been investigated. Two...

A Novel Magnetic Molecularly Imprinted Polymers Nanoparticle as Extracting Medium For Micro-Solid Phase Extraction

, M.Sc. Thesis Sharif University of Technology Yahya Baktash, Mohammad (Author) ; Bagheri, Habib (Supervisor)

Abstract

This thesis cantain two section. In the first section a novel extracting medium based on magnetic molecularly imprinted polymers (MIPs) nanoparticles was synthesized by chemical polymerization for micro-solid phase extraction. In this work, the modified chitosan magnetite nanoparticles (MNP-CS) was synthesized by co-precipitating Fe2+ and Fe3+ in the chitosan solution [1,2]. The characteristic properties of Fe3O4@MIPs nanoparticles were determined using Fourier transform infrared spectrometer. Extraction efficiency of the novel extracting medium was compared with MNP-CS sorbents for the determination of RhB in aqueous samples, via quantification by spectrofluorimetry. The obtained results...

Shaping of Laser Pulse for Molecular Dissociation

, M.Sc. Thesis Sharif University of Technology Rasti, Soroush (Author) ; Saddighi Bonabi, Rasoul (Supervisor)

Abstract

In this project, ionization and dissociation of nitrogen, methane and formaldehyde molecules through interaction by intense femto-second lasers have been investigated. The optimum shape of laser pulses for dissociation of methane and formaldehyde molecules for controlling the dissociation paths into desired products are obtained. Based on time dependent density functional theory and quantum optimal control theory, the calculations are carried out in intensities at the range of 1014-1016 Wcm-2 with pulse durations of 4 -20fs. Octopus package is used as a powerful computational program. By using, quantum optimal control theory, optimum laser pulses with manipulation of amplitude, phase and...