Anatomical Surface Modeling Via Harmonic Fields

, M.Sc. Thesis Sharif University of Technology Gharechorloo, Shayli (Author) ; Fatemi Zadeh, Emad (Supervisor)

Abstract

Advancements in medical imaging, especially 3D imaging, leads to progressive growth of image processing for diagnosis, studying behavior of organs and development of disease. Therefore many researches have been done on segmentation, registration, modeling and 3D image refinement. In this thesis, we want to parameterize anatomic surfaces, using volume parameterization model.
Hippocampus is one of the most important components in brain that plays significant role in learning, memory, stress management and etc. There is been a theory that, shape and structure of hippocampus may change in diseases like Alzheimer, schizophrenia, chronic depression and epilepsy.
The aim of this research is...

Hippocmapal Protein Kinase Mζ Overexpression Effect on Cognitive Performance in a Rat Model of Alzheimer’s Disease

, M.Sc. Thesis Sharif University of Technology Amini, Niloufar (Author) ; Roosta Azad, Reza (Supervisor) ; Gholamipour Badie, Hamid (Supervisor)

Abstract

Alzheimer’s disease (AD) is a neurodegenerative disease which results in synaptic depression and complete destruction in neurons in the final stages. Many pathogenesis has so far been attributed to AD but the most commonly explained pathomechanism is based on the amyloid cascade theory which results in formation of amyloid beta plaques outside and hyper phosphorylated neurofibrillary tangles of tau protein inside the neurons. One of the most well-known symptoms of AD is the disability to learn and form new memories and transform them into long term memory. The most commonly studied mechanism in memory formation, is the “long term potentiation”. Although many mechanisms and molecules are...

Comparative Analysis of the Effect of Gamma-band Entrainment through Auditory Stimulation in AD Patients and Healthy Controls

, M.Sc. Thesis Sharif University of Technology Lahijanian, Mojtaba (Author) ; Aghajan, Hamid (Supervisor)

Abstract

As the most widespread form of mental disorders, Alzheimer’s disease (AD) remains among the main challenges in neurology and in the field of neuroscience. There are still no effective drugs to cure this disease or slow its progress, and prevention methods are still not even close to having established records. However, the onset of AD has been linked to certain dysfunctions of the oscillatory frequencies of the affected brain mainly in the gamma band. Hence, an approach to consider for reversing the damaging effects of AD could involve reviving such oscillations through stimulating the neuronal networks in the brain that are known to be the source of these oscillations. A recent research has...