Sharif Digital Repository

Stroke is the second most frequent cause of death and the leading cause of disability in the world. Some effective drugs have been developed for ischemic stroke, while the golden time of use is three hours. Therefore, if stroke is diagnosed quickly, its side effects can be greatly avoided. However, it is not possible to use conventional diagnostic methods in many cases at a short time. In this work, S100β, MMP-9 and D-Dimer biomarkers were selected for rapid diagnosis of stroke based on previous studies.For this purpose, electrochemical immunosensors were developed with advantages such as low cost, ease of use, the possibility to automating the device, suitable sensitivity, reproducibility,...