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Production of drug Loaded Microgels Using Microfluidic
, M.Sc. Thesis Sharif University of Technology ; Saadatmand, Maryam (Supervisor) ; Eskandari, Mahnaz (Supervisor)
Abstract
Microfluidic systems have the ability to produce microgels with uniform size distribution and spherical shape due to the laminar flow and better control of the flow rates. Spherical microgels with same size can be used as high-potential carriers for drug release. An important challenge in the production of these drug-carrying microgels is the simultaneous process of drug loading into microgels and their production. The overall goal of this project was to produce drug-carrying microgels with uniform size distribution that show controlled drug release. To achieve this goal, various factors such as the type of polymer, the type of drug, the volume ratio of the polymer and the drug and the...