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Synthesis of Rhodanine-Oxindole Derivatives by Using Multi-Component Reactions in Green Solvent
, M.Sc. Thesis Sharif University of Technology ; Matloubi Moghaddam, Firouz (Supervisor)
Abstract
Nowadays, heterocyclic compounds have become extremely important in various industries, especially the pharmaceutical industry.In this project, an efficient and environmentally friendly path is presented to synthesize numerous rhodanine-oxindole derivatives in polyethylene Glycol in one pot-four components procedure. This pathway doesn't need harsh reaction conditions such as high temperature, long time, catalysts, complicated separation steps, toxic solvents, etc. all products have been made under green strategy with high yield.