Sharif Digital Repository

Development of new engineered materials for bone tissue engineering applications is rapidly growing. The most important characteristics of materials, which can be used for bone tissue engineering applications, are appropriate mechanical properties, degradation rate, swelling behavior, and bioactivity. The goal of the current investigation is to study the feasibility of incorporating a modified nano-biocomposite based on biodegradable thermoplastic starch for bone tissue engineering. Nano particles of ?-tricalcium phosphate and hydroxyapatite were incorporated for reinforcing the matrix as well as improving the bioactivity. A second biodegradable polymer, i.e. polycaprolactone, was used... 

Repairing and regeneration of neural tissues have attracted considerable attention due to its direct effect on the quality of patients’ lives. Recent developments in nanotechnology and tissue engineering have facilitated their comprehensive applications in the treatment of neurological diseases, and several effective ways have been proposed to repair defects in neural tissues. The main objective of the researches in this field is to regulate cellular behavior and tissue progression through the design and development of synthetic extracellular matrices, such as novel biomaterials, that enhance cell culture and tissue regeneration. Natural polymers, such as chitosan and gelatin, are suitable... 

In this work, a biocompatible sorbent based on halloysite nanotubes-zein bionanocomposite for direct-immersion thin film microextraction (DI-TFME) is introduced. Zein as a biodegradable, low cost and accessible polymer was used to prepare a flexible thin film with the possession of different interactions and good adsorption capacity. To improve the mechanical and chemical resistance of the film, halloysite nanotubes were combined with zein to prepare the thin film sorbent. The film was used for TFME of 16 pesticides from different chemical classes, including organochlorines and organophosphates followed by gas chromatography with electron capture detector (GC-ECD). To achieve the maximum...