Preparation and Application of the Glassy Carbon Electrodes Modified with Carbon Nanomaterials for Studies of the Electrochemical Behavior and Quantitative Determination of Metoclopramide and Furazolidone

, M.Sc. Thesis Sharif University of Technology Naderi, Leila (Author) ; Shahrokhian, Saeed (Supervisor)

Abstract

In the first part, a novel electrochemical sensor based on nanocellulose-carbon nanoparticles (NC–CNPs) nanocomposite film modified glassy carbon electrode (GCE) is developed for the analysis of metoclopramide (MCP). The electrochemical behavior of MCP was investigated on the surface of the modified electrode using cyclic voltammetry (CV). Characterization of the surface morphology and properties of NC/CNPs was carried out by scanning electron microscopy (SEM), atomic force microscopy (AFM) and electrochemical impedance spectroscopy (EIS). Effective experimental variables, such as scan rate, pH of the supporting electrolyte, drop size of the casted modifier suspension and accumulation...

Preparation and Investigation of the Electrochemical of the Glassy Carbon Electrode Modified by Nanocellulose/Carbon Nanoparticle: Application to Pharmaceutical Determinations

, M.Sc. Thesis Sharif University of Technology Balotf, Hamed (Author) ; Shahrokhian, Saeed (Supervisor)

Abstract

In the first part, a novel electrochemical sensor for clonazepam (CLNP) was fabricated based on immobilizing cellulose nanofibers /carbon nanoparticles (CNFs/CNPs) nanocomposite on glassy carbon electrode (CNFs/CNPs/GCE). The combination of CNFs and CNPs produced a novel kind of structurally uniform and electro-analytically active nanocomposite. The surface morphology of CNFs/CNPs layer deposited onto glassy carbon electrode was characterized by scanning electron microscopy. The results of the voltammetric investigations showed a considerable enhancement in the cathodic peak current of CLNP (up to 60 times) on the surface of CNFs/CNPs/GCE relative to the bare GCE. Under the optimal...

Synthesis and Evaluation of Poly(lactic Acid)/Polyurethane Nano-composites based on Cellulose Nano-particles, with Biomedical Applications

, M.Sc. Thesis Sharif University of Technology Mohammadian Ahrabi, Taha (Author) ; Shojaei, Akbar (Supervisor) ; Salkhi Khasraghi, Samaneh (Co-Supervisor)

Abstract

Shape memory polymers have the potential to use in the field of biomedical applications. In this research, polyurethane structures have been synthesized based on the Diol mixtures, consisting of polycaprolactane diol (PCL-diol) and poly (lactic acid) diol (PLA-diol). Aim of reasearch is about evaluating poly (lactic acid) effect in structure of the polyurethane. At the same time, cellulose nanocrystals (CNC) have been added to polymer matrix to improve properties. The synthesis of acrylated polyurethane, included the synthesis of polyurethane acrylate prepolymer. Next, this prepolymer has been cured by adding the reactive diluent and some polyol. The cured systems were investigated, finally,...

Developments of Fluorescence Sensor Arrays Using Nanostructured Sensor Elments and Nanocellulose Substrate for Identification and Discrimination of Biomolecules and Environmental pollutants

, Ph.D. Dissertation Sharif University of Technology Abbasi-Moayed, Samira (Author) ; Hormozi-Nezhad, Mohammad Reza (Supervisor) ; Golmohammadi Ghaneh, Hamed (Co-Supervisor)

Abstract

In the first part of this research, a ratiometric fluorescent sensor array has been developed on nanocellulose platform towards chemical discrimination applications. Bacterial nanocellulose (BC) was utilized for the first time as a novel, flexible and transparent substrate in optical sensor arrays for developing portable and high performance sensor array.. To fabricate this platform, the hydrophobic walls on BC nanopaper substrates were successfully created using laser printing technology. In addition, we have used the properties of immobilized ratiometric fluorescence sensor elements (Carbon Dots- Rhodamine B (CDs-RhB) nanohybrids) on nanopaper platform to improve the visual...

Alginate/CNC Hydrogel Nanocomposites as Adsorbents of Water Pollutants

, M.Sc. Thesis Sharif University of Technology Mousavi, Yeganeh (Author) ; Frounchi, Masoud (Supervisor)

Abstract

With the increase in population, industrial advancements, and urbanization, the demand for clean water resources has risen. However, industrial pollutants, particularly heavy metals, pose a significant threat to aquatic ecosystems, necessitating their removal from wastewater. Among various methods, surface adsorption using hydrogels has proven to be effective. This research aims to develop hydrogels from sodium alginate and carboxymethyl nanocellulose for the adsorption of heavy metals, specifically copper and nickel, from wastewater. The results indicate that increasing the percentage of nanocrystalline cellulose enhances the hydrogel's swelling rate, while higher alginate content...