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Biomolecules and Polymers Translocation Through Biological Single Nanopores and Current Characteristics Analysis
, Ph.D. Dissertation Sharif University of Technology ; Ejtehadi, Mohammad Reza (Supervisor) ; Mobasheri, Hamid (Co-Advisor)
Abstract
Translocation processes are ubiquitous in biology and biotechnology. Translocation of small molecules, e. g. sugar from maltoporin, metabolites through bacteria and macromolecules like proteins, from channels of cellular organelles and or RNA translocation though
nuclear pores are of vital importance for cellular metabolism. One of the important applications of translocation processes in biotechnology is to sense translocating macromolecules or small molecules by analyzing the current passing through natural or synthesis channels. Improving our knowledge about this process can also help us to develop new methods for designing the appropriate drugs. In this thesis by studying and...
nuclear pores are of vital importance for cellular metabolism. One of the important applications of translocation processes in biotechnology is to sense translocating macromolecules or small molecules by analyzing the current passing through natural or synthesis channels. Improving our knowledge about this process can also help us to develop new methods for designing the appropriate drugs. In this thesis by studying and...