Sharif Digital Repository

Referring to mortality increasment having sprung from atherosclerosis, work on treatment of coronary heart disease seems to be necessary. Stent implementation is one of stenosis treatment. Stent deployment has been done during past two decades, but clinical evidence showed that because of some weakness in designing and implementing, restenosis occurs again. Material, structure and coating texture of stent are the designing criteria beside stent implementation importance. Thus a lot of activities have been done in this area to improve performance of these applications. Nowadays a lot of companies' researchers try the best to get better their products; consequently there is different types of... 

Due to increased mortality from Coronary Heart Disease, it is important to work on ways to treat this disease. An effective method of treatment on this disease is the coronary stent implantation. There are nearly two decades passed since implanting the first heart stent. The main objective of this research is design and manufacturing of the medical stents of stainless steel 316 L. Stent materials should have excellent corrosion resistance and biocompatibility. Various materials such as stainless steel 316 L, platinum alloys, niobium alloys, cobalt alloys are used for manufacturing the stents. In this project, at the first stage seam tube was prodected with laser welding of a tube with... 

Magnesium and its alloys have gained much attention in medical applications, especially bio-degradable stents. However, they have not been used extensively due to their natural limitations, such as weak mechanical properties. WE43 magnesium alloy has gained attention as a bio-alloy due to its high temperature and good corrosion resistance. The present study aims to use a combination of ECAP and direct tube extrusion to fabricate thin wall tubes with good mechanical properties using WE43 magnesium alloy. In the first phase, the ECAP process at 370°C were conducted up to 4 passes on the homogenized samples to reach ultrafine grain structure. Subsequent to ECAP, direct tube extrusion at 230 °C,... 

The present study examines the mechanical properties of auxetic stents with various types of structures. Geometries was parametrically modeled and the design of experiments (DOE) was developed by defining the elastic properties of the stents and using the response surface method (RSM). Finite element (FE) analysis was performed in order to find a polynomial relationship between the geometric parameters as inputs and the elastic parameters as the outputs. Then, the optimal stent was obtained in terms of elasticity parameters by using RSM and NSGA-II methods and the two-dimensional Pareto front was plotted. For instance, the optimal parameters of the Re-entrant stent including flexural... 

Properties of stents are significantly dependent on the mechanical properties of the microtubes used in their construction. Therefore, investigating the influence of various factors on the mechanical behavior of magnesium microtubes employed in the fabrication of biodegradable stents can play an indispensable role in the development of the emerging industry of biodegradable stent manufacturing. In this dissertation, the effects of different parameters on the mechanical behavior of magnesium microtubes used in the construction of biodegradable stents have been examined. To achieve this, the objectives of this dissertation have been divided into three main sections. In the first section, a...