Sharif Digital Repository

Superparamagnetic iron oxide nanoparticles (SPION) with proper surface coatings are increasingly being evaluated for clinical applications such as hyperthermia, drug delivery, magnetic resonance imaging, transfection, and cell/protein separation. Since the particles with various sizes exhibit different flow rates in the same environment (same capillary size), it is essential to use particles of a desirable size for targeted drug delivery and imaging. Particles of different sizes may be exposed to different viscosities and behave differently, particularly with regard to their velocities as they move through capillaries. In the present work, SPION with different size, purity, shape and... 

Optimizing optical tweezers and achieving powerful traps has always been a challenging topic for researchers , since the trap stiffness increases with increasing laser power which may damage specimens , especially biological ones and cells . In this thesis , we introduce a special geometry and structure of particles that , have the possibility to increase the stiffness (strength) of the optical trap and cause the magnetic response of particles at optical frequencies . Special geometries such as a combination of dielectric particles with magnetic nanoparticles that emphasize the role of the laser magnetic field and lead to changes in the electrical and magnetic properties at the laser...