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- Type of Document: M.Sc. Thesis
- Language: Farsi
- Document No: 43089 (08)
- University: Sharif University of Technology
- Department: Mechanical Engineering
- Advisor(s): Firoozbakhsh, Keikhosrow
- Abstract:
- Articular cartilage Function is vital to joint tasks and its motion. The main biomechanical tasks of articular cartilage are a) the distribution of loads occurred in joints; b) providing joints with frictionless surface. The particular mechanical properties of articular cartilage make it possible for the Cartilage tissue to do its duty successfully. The biological factor that causes articular cartilage to damage is still unknown. It is believed that mechanical factors are the main reason for the cartilage destruction in osteoarthritis. Factors like age, heavy exercises and impact can begin tissue destructions and result in change in mechanical properties. To study the process of the articular cartilage damage and the osteoarthritis disease, the stress and strain fields inside the tissue must be specified first.In this study to predict the mechanical behavior of AC, using the results of the displacement field inside AC in the confined compression condition, a model is suggested whose mechanical properties vary from the tissue surface to its depth. In addition, manufacturing of the synthetic Cartilage similar to the actual tissue is possible. For this purpose, nonlinear biphasic inhomogeneous model has been used. Tow homomogeneous and inhomogeneous models (in which the tissue stiffens from the surface to its depth) were presented and the governing equations in AC were solved by finite difference method and the results were compared with experimental data. The results show that the inhomogeneous model has a good correlation with the actual behavior of the tissue
- Keywords:
- Collagen ; Articular Cartilage ; Compressive Modulus ; Protoglycan
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