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Modeling, Simulation and Characterization of Blood Treatment and Filtration Process in Home Hemodialysis Machines

Masoumi, Arezou | 2012

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  1. Type of Document: M.Sc. Thesis
  2. Language: English
  3. Document No: 43364 (58)
  4. University: Sharif University of Technology, International Campus, Kish Island
  5. Department: Science and Engineering
  6. Advisor(s): Saeedi, Mohammad Saeed
  7. Abstract:
  8. Dialysis which is an imperfect but most common treatment option for renal failure is divided into two main types:"peritoneal dialysis" and "hemodialysis". Peritoneal dialysis uses a fluid that is placed into the patient's stomach cavity through a special plastic tube to remove excess waste products and fluid from the body.Hemodialysis uses a special type of filter to remove excess waste products and water from the body and is divided to two groups :Clinical and Home.During hemodialysis, blood passes from the patient's body through a filter in the dialysis machine. In this Study first the basic aspect of renal failure and principle of dialysis process are described.Then information about different hemodialysis machines available in the market, focusing the survey on national market, is given. Next, a specific type of hemodialysis machines, NxStage Home hemodialysis machine, is selected to investigate its operational characteristics. The main purpose of this study is to use an effective and reliable CFD model,” Double Porous Media model”, to simulate mass transfer inside of hemodialyzer which is the main component of extracorporeal circuit in NxStage home hemodialysis machines. In order to verify the result, geometric and transport parameters of the CT190G dialyzer module have been used in simulation and then comparison of experimental and numerical results has been done.

  9. Keywords:
  10. Hemodialysis ; Double Porous Media ; Mixture Model ; Clearance

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