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Highly efficient ring opening reactions of epoxides with deactivated aromatic amines catalyzed by heteropoly acids in water

Azizi, N. (Najmodin) ; Sharif University of Technology

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  1. Type of Document: Article
  2. DOI: 10.1016/j.tet.2006.11.045
  3. Abstract:
  4. Heteropoly acid was found to be an effective and efficient catalyst for the ring opening reaction of epoxides with various aromatic amines to produce the corresponding β-amino alcohols in moderate to excellent yields in water. This method provides a new and efficient protocol in terms of mild reaction conditions, clean reaction profiles, small quantity of catalyst, and simple work-up procedure
  5. Keywords:
  6. Amino alcohol ; Aromatic amine ; Epoxide ; Heteropoly acid ; Atom economy ; Water chemistry
  7. Source: Tetrahedron ; 2007, Volume 63, Issue 4, Pages 888–891
  8. URL: http://www.sciencedirect.com/science/article/pii/S0040402006018461