Simulation of Paramecium Swimming in an Environment with a Chemical Gradient

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Nematollahi Sarvestani, Ali | 2014

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Type of Document: M.Sc. Thesis
Language: Farsi
Document No: 45941 (08)
University: Sharif University of Technology
Department: Mechanical Engineering
Advisor(s): Ahmadian, Mohammad Taghi; Shamloo, Amir
Abstract:
In the recent decade, researchers in the field of minimally invasive medicine have come up to the idea of utilizing micro organisms as smart micro robots. The advantage with this idea is the fact that problems such as energy supply and maneuvering are resolved for these sorts of micro swimmers. In this current work, a new numerical method for investigation of micro swimming is developed which is computationally efficient in characterizing locomotion of micro swimmers and using a finite element method software, locomotion of Paramecium has been investigated inside and outside a capillary tube. According to simulation results, it is possible to design a controlling system which is capable of guiding Paramecium to a desired destination by inducing a certain type of Calcium gradient in the swimming micro environment. This system enables us to utilize Paramecium for targeted drug delivery, tissue sampling and imaging in vivo
Keywords:
Microswimmer ; Chemotaxis ; Minimaly Invasive Surgery (MIS) ; Low-Reynolds Flows

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