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Efficient deep eutectic solvents catalyzed synthesis of pyran and benzopyran derivatives

Azizi, N ; Sharif University of Technology | 2013

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  1. Type of Document: Article
  2. DOI: 10.1016/j.molliq.2013.05.011
  3. Publisher: 2013
  4. Abstract:
  5. An ecofriendly one-pot multicomponent reaction of 1,3-dicarbonyl compounds, aldehydes, and malononitrile was carried out in a different deep eutectic solvent (DES) based on choline chloride, to synthesize highly functionalized benzopyran and pyran derivatives under catalyst-free conditions. The results showed that urea:choline chloride based DES is the best solvent and is successfully applicable to a wide range of aldehydes, active methylene compounds with high yields (75-95%) and short reaction times (1-4 h)
  6. Keywords:
  7. Benzopyran ; Choline chloride ; Deep eutectic solvent ; Green chemistry ; Deep eutectic solvents ; Pyran ; Aldehydes ; Chlorine compounds ; Urea ; Ionic liquids
  8. Source: Journal of Molecular Liquids ; Volume 186 , 2013 , Pages 76-80 ; 01677322 (ISSN)
  9. URL: http://www.sciencedirect.com/science/article/pii/S0167732213001803