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Biomedical applications of carbon nanotube's supramolecules

Adeli, M ; Sharif University of Technology | 2012

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  1. Type of Document: Article
  2. Publisher: Nova Science Publishers, Inc , 2012
  3. Abstract:
  4. Among diverse classes of hybrid nanomaterial-based drug delivery systems (HNDDSs) those based on the carbon nanotubes have attracted particular attention as carriers for the biologically relevant molecules due to their unique properties such as ability to cross the cell membranes and high surface area per unit weight for the high drug loading. Varity of HNDDSs based on the carbon nanotubes have been prepared and tested in vitro and in vivo for delivery of the drugs recently.Poor water solubility and low functionality are two critical factors that influence the performance of the CNTs for biomedical applications. Therefore, in order to make HNDDSs based on CNTs these factors should be improved. Solubility of CNTs can be developed by treatment with polymers either covalently or noncovalently. Non-covalent method is based on the supramolecular interactions between CNTs and polymers and includes polymer wrapping or adsorption. In this method the structure of the CNTs does not change as much as the covalent method, but its disadvantage is the low functionality of the final product
  5. Keywords:
  7. Source: Hybrid Nanostructures in Cancer Therapy ; 2012 , Pages 69-96 ; 9781621005179 (ISBN)
  8. URL: https://www.novapublishers.com/catalog/product_info.php?products_id=29121&osCsid