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Efficient synthesis of bicyclo[3.3.1]nonane systems via tandem 1,3-dinucleophilic addition of 4-hydroxy-2-quinolinones to quinolinium salts

Moghaddam, F. M ; Sharif University of Technology | 2012

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  1. Type of Document: Article
  2. DOI: 10.1080/00397911.2010.550703
  3. Publisher: 2012
  4. Abstract:
  5. The synthesis of bicyclo[3.3.1]nonane systems is reported. The synthesis is based on the tandem 1,3-dinucleophilic addition of 4-hydroxy-2-quinolinone to quinolinium salts
  6. Keywords:
  7. 1,3-dinucleophilic addition ; Benzoxazocines ; Quinolinium salts ; Quinolinones ; 2 benzyl 9 ethyl 2,8,9,14 tetrahydro 1h 8,14 methanoquino (4,3 dextro) (3,1) benzoxazocin 1 one ; 2 benzyl 9 methyl 2,8,9,14 tetrahydro 1h 8,14 methanoquino (4,3 dextro) (3,1) benzoxazocin 1 one ; 2 benzyly 9, 12 dimethyl 2,8,9,14 tetrahydro 1h 8,14 methanoquino (4,3 dextro) (3,1) benzoxazocin 1 one ; 2,8,9 trimethyl 2,8,9,14 tetrahydro 1h 8,14 methanoquino (4,3 dextro) (3,1) benzoxazocin 1 one ; 2,9 dimethyl 2,8,9,14 tetrahydro 1h 8,14 methanoquino (4,3 dextro) (3,1) benzoxazocin 1 one ; 2,9,12 trimethyl 2,8,9,14 tetrahydro 1h 8,14 methanoquino (4,3 dextro) (3,1) benzoxazocin 1 one ; 4 hydroxy 2 quinolinone derivative ; 9 allyl 2 methyl 2,8,9,14 tetrahydro 1h 8,14 methanoquino (4,3 dextro) (3,1) benzoxazocin 1 one ; 9 ethyl 2 methyl 2,8,9,14 tetrahydro 1h 8,14 methanoquino (4,3 dextro) (3,1) benzoxazocin 1 one ; Ethyl [2 methyl 1 oxo 2,14 dihydro 1h 8,14 methanoquino (4,3 dextro) benzoxacin 9 yl] acetate ; Quinolinium salt ; Quinolinol derivative ; Unclassified drug ; Chemical reaction ; Drug structure ; Drug synthesis
  8. Source: Synthetic Communications ; Volume 42, Issue 13 , 2012 , Pages 1941-1949 ; 00397911 (ISSN)
  9. URL: http://www.tandfonline.com/doi/abs/10.1080/00397911.2010.550703