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Rotating field gradient (RFG) MR offers improved orientational sensitivity

Ozarslan, E ; Sharif University of Technology | 2015

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  1. Type of Document: Article
  2. DOI: 10.1109/ISBI.2015.7164029
  3. Publisher: IEEE Computer Society , 2015
  4. Abstract:
  5. Rotating field gradients (RFGs), generated by simultaneously applying sine- and cosine-modulated gradient waveforms along two perpendicular directions, provide an alternative diffusion sensitization mechanism for magnetic resonance imaging and spectroscopy. Two RFGs with a 90-degree phase shift between them are applied around the 180-degree RF pulse in a spin echo sequence to measure the diffusion orientation distribution function (dODF) directly. The technique obviates transforming the data from a space reciprocal to the displacement space. Here, we compare RFG results with those obtained by two pulsed field gradient (PFG) techniques: q-ball imaging (QBI) and its extension to constant solid angles (CSA). Our results indicate that RFG provides more accuracy than QBI, while the spurious peaks encountered with the QBI-CSA approach are absent when the RFG-based technique is used. These observations suggest the superior performance of RFG-based methods for mapping the anatomical connections within the nervous system
  6. Keywords:
  7. Mi-crostructure ; MRI ; Orientation ; Anisotropy ; Crystal orientation ; Distribution functions ; Magnetic resonance imaging ; Medical imaging ; Metadata ; Phase shift ; Phase shifters ; Connectivity ; Connectome ; RFG ; Rotating ; Tractography ; White matter ; Diffusion
  8. Source: Proceedings - International Symposium on Biomedical Imaging, 16 April 2015 through 19 April 2015 ; Volume 2015-July , 2015 , Pages 955-958 ; 19457928 (ISSN) ; 9781479923748 (ISBN)
  9. URL: http://ieeexplore.ieee.org/document/7164029/?reload=true