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A tandem aldol-diels-alder reaction accelerated in water: An approach to the catalyst-free one-pot synthesis of spiro thio-oxindoles

Matloubi Moghaddam, F ; Sharif University of Technology | 2010

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  1. Type of Document: Article
  2. Publisher: 2010
  3. Abstract:
  4. Spiro thio-oxindoles are prepared in situ by the reaction of the corresponding aldehydes and thio-oxindoles in a straightforward, environmentally friendly, highly efficient and simple procedure. The reaction took place in water with no catalyst added. This one-pot reaction afforded regio- and diastereoselective products in high yields (61-93%)
  5. Keywords:
  6. α,β-Unsaturated thio-oxindole ; Aldol-Diels-Alder reaction ; Dimerization ; Spiro thio-oxindoles
  7. Source: Journal of the Iranian Chemical Society ; Volume 7, Issue 3 , September , 2010 , Pages 781-790 ; 1735207X (ISSN)
  8. URL: http://link.springer.com/article/10.1007/BF03246069