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An efficient ZnO-catalyzed synthesis of novel indole-annulated thiopyrano-chromene derivatives via Domino Knoevenagel-hetero-Diels-Alder reaction

Kiamehr, M ; Sharif University of Technology

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  1. Type of Document: Article
  2. DOI: 10.1016/j.tetlet.2009.09.106
  3. Abstract:
  4. An efficient synthesis of pentacyclic indole derivatives is achieved via domino Knoevenagel-hetero-Diels-Alder reactions of indolin-2-thiones and O-propargylated salicylaldehyde derivatives in CH3CN in the presence of 10 mol % of ZnO as a heterogeneous catalyst. The products are formed in good to excellent yields
  5. Keywords:
  6. Hetero-Diels-Alder reaction ; Indolin-2-thione ; Knoevenagel reaction ; O-propargylated salicylaldehyde ; ZnO ; Indole derivative ; Thiopyrano chromene derivative ; Unclassified drug ; Zinc oxide ; Article ; Catalysis ; Diels Alder reaction ; Knoevenagel condensation ; Alnus
  7. Source: Tetrahedron Letters ; Volume 50, Issue 48 , 2009 , Pages 6723-6727 ; 00404039 (ISSN)
  8. URL: http://www.sciencedirect.com/science/article/pii/S0040403909018395