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Convenient synthesis of chlorohydrins from epoxides using zinc oxide: Application to 5,6-epoxysitosterol

Matloubi Moghaddam, F ; Sharif University of Technology | 2009

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  1. Type of Document: Article
  2. DOI: 10.1002/hc.20529
  3. Publisher: 2009
  4. Abstract:
  5. Efficient synthesis of protected and unprotected chlorohydrins has been achieved by ring opening of epoxides with acetyl/benzoyl chloride and TMSCl using a catalytic amount of ZnO as a reusable catalyst. The applicability of ZnO is further extended by performing the cleavage of the natural product 5,6-epoxysitosterol with acetyl chloride. © 2009 Wiley Periodicals, Inc
  6. Keywords:
  7. Acetyl chloride ; Catalytic amounts ; Efficient synthesis ; Natural products ; Reusable catalysts ; Ring opening of epoxide ; ZnO ; Chlorine compounds ; Computer software reusability ; Semiconducting zinc compounds ; Zinc ; Zinc oxide
  8. Source: Heteroatom Chemistry ; Volume 20, Issue 3 , 2009 , Pages 157-163 ; 10427163 (ISSN)
  9. URL: https://onlinelibrary.wiley.com/doi/abs/10.1002/hc.20529