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A new and facile synthesis of thieno[2,3-b]indole derivatives via condensation of isocyanide and indolin-2-thiones

Matloubi Moghaddam, F ; Sharif University of Technology | 2009

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  1. Type of Document: Article
  2. DOI: 10.1055/s-0028-1088107
  3. Publisher: 2009
  4. Abstract:
  5. A new one-pot synthesis of thieno[2,3-b]indole ring systems is described. Condensation of cyclohexyl isocyanide with indolin-2-thiones yielded 3-cyclohexyaminomethylene-indolin-2-thiones, which upon reaction with α-halocarbonyl compounds produced the title compounds. © Georg Thieme Verlag Stuttgart
  6. Keywords:
  7. Isocyanide ; Thieno[2,3-b]indole derivatives ; Thioamide ; 3 cyclohexyaminomethylene indolin 2 thione ; Antifungal agent ; Cyanide ; Indole derivative ; Unclassified drug ; Carbon nuclear magnetic resonance ; Chemical reaction ; Controlled study ; Drug determination ; Drug structure ; Drug synthesis ; One pot synthesis ; Polymerization ; Proton nuclear magnetic resonance
  8. Source: Synlett ; Issue 7 , 2009 , Pages 1047-1050 ; 09365214 (ISSN)
  9. URL: https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0028-1088107