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Dynamic analysis of magnetic nanoparticles crossing cell membrane

Pedram, M. Z ; Sharif University of Technology | 2017

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  1. Type of Document: Article
  2. DOI: 10.1016/j.jmmm.2016.07.023
  3. Publisher: Elsevier B.V , 2017
  4. Abstract:
  5. Nowadays, nanoparticles (NPs) are used in a variety of biomedical applications including brain disease diagnostics and subsequent treatments. Among the various types of NPs, magnetic nanoparticles (MNPs) have been implemented by many research groups for an array of life science applications. In this paper, we studied MNPs controlled delivery into the endothelial cells using a magnetic field. Dynamics equations of MNPs were defined in the continuous domain using control theory methods and were applied to crossing the cell membrane. This study, dedicated to clinical and biomedical research applications, offers a guideline for the generation of a magnetic field required for the delivery of MNPs. © 2016 Elsevier B.V
  6. Keywords:
  7. Blood Brain Barrier ; Cell membrane ; Dynamics simulation ; Magnetic nanoparticles (MNPs) ; Cell membranes ; Cells ; Cytology ; Diagnosis ; Endothelial cells ; Magnetic fields ; Magnetism ; Medical applications ; Nanoparticles ; Biomedical applications ; Biomedical research ; Blood-brain barrier ; Controlled delivery ; Magnetic nano-particles ; Magnetic nanoparti cles (MNPs) ; Nanoparticle (NPs) ; Nanomagnetics
  8. Source: Journal of Magnetism and Magnetic Materials ; Volume 422 , 2017 , Pages 464- ; 03048853 (ISSN)
  9. URL: https://www.sciencedirect.com/science/article/abs/pii/S0304885316334941