Design of a Low Frequency Magnetic Hyperthermia System for Cancer Treatment

Please enable javascript in your browser.

Jahadi Naeini, Alireza | 2018

451 Viewed

Type of Document: M.Sc. Thesis
Language: Farsi
Document No: 50618 (05)
University: Sharif University of Technology
Department: Electrical Engineering
Advisor(s): Shishegar, Amir Ahmad
Abstract:
Low frequency Magnetic hyperthermia is a promising cancer treatment technique. It is based on the fact that magnetic nanoparticles (MNPs) placed in an alternating magnetic field release heat.Active research is being done to improve the specific absorption rate (SAR) of MNPs, which could permit the treatment of tumors of a smaller size and could reduce the amount of material that must be injected to treat a tumor of a given size. However, a major technical problem with hyperthermia is the difficulty of heating the targeted tumor to the desired temperature without damaging the surrounding tissues, as the electromagnetic energy must be directed from an external source and penetrates normal tissue. In this study the design of magnetic hyperthermia system is aimed, obviously it involves all aspects including nanoparticle optimization, magnetic field tuning and matching these two parts. We have presented two concepts, first one is targeted (MH) system which increase focus of heating and second one is modulated excitation which could be an efficient way for SAR enhancement
Keywords:
Hyperthermia ; Electromagnetic Fields ; Cancer Treatment ; Low Frequency Electromagnetic Field ; Neel and Brownian Dirriapation ; Supermagnetism

No TOC