Loading...

Investigation the Effect of Conductive Scaffolds on Regeneration of the Heart Tissue

Moradpour, Kayvan | 2020

1682 Viewed
  1. Type of Document: M.Sc. Thesis
  2. Language: Farsi
  3. Document No: 53450 (06)
  4. University: Sharif University of Technology
  5. Department: Chemical and Petroleum Engineering
  6. Advisor(s): Vossoughi, Manoochehr; Ahmadi Tafti, Hossein
  7. Abstract:
  8. Cardiovascular diseases, especially coronary artery disease and coronary heart disease, are the leading cause of death in human communities. After myocardial infarction, known as heart attack, the flow of oxygen to the heart muscle cells is disrupted. It causes the death of cells that leads to structural and functional changes in the heart muscle. Therefore, specialists try to find a way to repair and regenerate the heart muscle after myocardial infarction. Tissue engineering is used to develop substantial alternatives to assist clinical therapies. Recent studies have focused on the construction of scaffolds with various advanced techniques to create guiding channels that mimic the natural regeneration process in the human body and resemble the extracellular matrix (ECM). Scaffold with a highly porous microstructure comprising high mechanical strength and large surface area, that enables food supply and transport, promotes tissue growth and provides a suitable space for migration and attachment of cardiac cells for regeneration of damaged tissue. The aim of this study was transducing myocardial progenitor cells onto an electrospun scaffold of nylon 6 and polyurethane, that has a higher conductivity due to the usage of multiwall conductive carbon nanotube (MWCNT) nanoparticles, and then, growth and examining of the scaffold
  9. Keywords:
  10. Heart Tissue Engineering ; Carbon Nanotubes ; Polyurethane ; Nylon 6 ; Heart Regeneration ; Conductive Scaffold ; Multi-Walled Carbon Nanotube

 Digital Object List

 Bookmark

...see more